CN101225082A - 一种从茶叶中提取茶多酚和分离单体egcg的方法 - Google Patents
一种从茶叶中提取茶多酚和分离单体egcg的方法 Download PDFInfo
- Publication number
- CN101225082A CN101225082A CNA2008100595670A CN200810059567A CN101225082A CN 101225082 A CN101225082 A CN 101225082A CN A2008100595670 A CNA2008100595670 A CN A2008100595670A CN 200810059567 A CN200810059567 A CN 200810059567A CN 101225082 A CN101225082 A CN 101225082A
- Authority
- CN
- China
- Prior art keywords
- tea
- polyphenol
- tealeaves
- solid phase
- alkali reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 53
- 239000000178 monomer Substances 0.000 title claims abstract description 28
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 title claims abstract 17
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 title claims abstract 17
- 241001122767 Theaceae Species 0.000 title claims abstract 16
- 239000003513 alkali Substances 0.000 claims abstract description 75
- 239000007790 solid phase Substances 0.000 claims abstract description 72
- 239000000706 filtrate Substances 0.000 claims abstract description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000006228 supernatant Substances 0.000 claims abstract description 11
- 239000012043 crude product Substances 0.000 claims abstract description 4
- 150000007522 mineralic acids Chemical class 0.000 claims abstract description 3
- 239000003153 chemical reaction reagent Substances 0.000 claims description 71
- 238000001035 drying Methods 0.000 claims description 30
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 24
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 13
- 239000000428 dust Substances 0.000 claims description 13
- 235000017550 sodium carbonate Nutrition 0.000 claims description 12
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 12
- 239000002253 acid Substances 0.000 claims description 9
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 8
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 8
- 235000010755 mineral Nutrition 0.000 claims description 8
- 239000011707 mineral Substances 0.000 claims description 8
- 235000012204 lemonade/lime carbonate Nutrition 0.000 claims description 7
- 235000019353 potassium silicate Nutrition 0.000 claims description 7
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 6
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 6
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 claims description 6
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 6
- 229910000397 disodium phosphate Inorganic materials 0.000 claims description 6
- 235000019800 disodium phosphate Nutrition 0.000 claims description 6
- 239000002245 particle Substances 0.000 claims description 5
- 238000001556 precipitation Methods 0.000 claims description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 3
- 229910021502 aluminium hydroxide Inorganic materials 0.000 claims description 3
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 2
- LBPACUJFGRCWDF-UHFFFAOYSA-L Cl[Mg]Cl.[Na] Chemical compound Cl[Mg]Cl.[Na] LBPACUJFGRCWDF-UHFFFAOYSA-L 0.000 claims description 2
- JJLJMEJHUUYSSY-UHFFFAOYSA-L Copper hydroxide Chemical compound [OH-].[OH-].[Cu+2] JJLJMEJHUUYSSY-UHFFFAOYSA-L 0.000 claims description 2
- 239000005750 Copper hydroxide Substances 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 2
- VTGNXADCFUDPLG-UHFFFAOYSA-N O(O)O.[Cu] Chemical compound O(O)O.[Cu] VTGNXADCFUDPLG-UHFFFAOYSA-N 0.000 claims description 2
- 239000004411 aluminium Substances 0.000 claims description 2
- 229910052782 aluminium Inorganic materials 0.000 claims description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 2
- 239000002585 base Substances 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 2
- 239000000920 calcium hydroxide Substances 0.000 claims description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims description 2
- 229910001956 copper hydroxide Inorganic materials 0.000 claims description 2
- 238000004090 dissolution Methods 0.000 claims description 2
- 239000011777 magnesium Substances 0.000 claims description 2
- 229910052749 magnesium Inorganic materials 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims description 2
- 239000000047 product Substances 0.000 abstract description 60
- 150000008442 polyphenolic compounds Chemical class 0.000 abstract description 32
- 235000013824 polyphenols Nutrition 0.000 abstract description 31
- 238000000605 extraction Methods 0.000 abstract description 7
- 238000000926 separation method Methods 0.000 abstract description 6
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 239000002904 solvent Substances 0.000 abstract description 3
- 238000001311 chemical methods and process Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000004062 sedimentation Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 description 28
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical group [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 26
- 238000003556 assay Methods 0.000 description 26
- 238000011156 evaluation Methods 0.000 description 25
- 238000003801 milling Methods 0.000 description 24
- 235000017557 sodium bicarbonate Nutrition 0.000 description 13
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 13
- 244000269722 Thea sinensis Species 0.000 description 8
- 238000005516 engineering process Methods 0.000 description 8
- 239000007791 liquid phase Substances 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- XMOCLSLCDHWDHP-IUODEOHRSA-N epi-Gallocatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-IUODEOHRSA-N 0.000 description 7
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 description 5
- 235000005487 catechin Nutrition 0.000 description 5
- 229950001002 cianidanol Drugs 0.000 description 5
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- LSHVYAFMTMFKBA-TZIWHRDSSA-N (-)-epicatechin-3-O-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=CC=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-TZIWHRDSSA-N 0.000 description 3
- 238000004587 chromatography analysis Methods 0.000 description 3
- 238000002386 leaching Methods 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 2
- XMOCLSLCDHWDHP-UHFFFAOYSA-N L-Epigallocatechin Natural products OC1CC2=C(O)C=C(O)C=C2OC1C1=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical group [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- 229960000583 acetic acid Drugs 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- DZYNKLUGCOSVKS-UHFFFAOYSA-N epigallocatechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3cc(O)c(O)c(O)c3 DZYNKLUGCOSVKS-UHFFFAOYSA-N 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- LCCDINSFSOALJK-UHFFFAOYSA-N 1,3,4-trimethylpurine-2,6-dione Chemical compound O=C1N(C)C(=O)N(C)C2(C)N=CN=C21 LCCDINSFSOALJK-UHFFFAOYSA-N 0.000 description 1
- 241001504664 Crossocheilus latius Species 0.000 description 1
- LSHVYAFMTMFKBA-UHFFFAOYSA-N ECG Natural products C=1C=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 235000014220 Rhus chinensis Nutrition 0.000 description 1
- 240000003152 Rhus chinensis Species 0.000 description 1
- DPDMMXDBJGCCQC-UHFFFAOYSA-N [Na].[Cl] Chemical group [Na].[Cl] DPDMMXDBJGCCQC-UHFFFAOYSA-N 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- -1 catechin gallic acid ester Chemical class 0.000 description 1
- 238000013375 chromatographic separation Methods 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000010262 high-speed countercurrent chromatography Methods 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 150000001455 metallic ions Chemical class 0.000 description 1
- 229940045641 monobasic sodium phosphate Drugs 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical group [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 239000002910 solid waste Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 238000003807 solvent-free extraction Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- RYYVLZVUVIJVGH-UHFFFAOYSA-N trimethylxanthine Natural products CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000002912 waste gas Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Landscapes
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2008100595670A CN101225082B (zh) | 2008-01-31 | 2008-01-31 | 一种从茶叶中提取茶多酚和分离单体egcg的方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2008100595670A CN101225082B (zh) | 2008-01-31 | 2008-01-31 | 一种从茶叶中提取茶多酚和分离单体egcg的方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101225082A true CN101225082A (zh) | 2008-07-23 |
CN101225082B CN101225082B (zh) | 2010-12-01 |
Family
ID=39857318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2008100595670A Expired - Fee Related CN101225082B (zh) | 2008-01-31 | 2008-01-31 | 一种从茶叶中提取茶多酚和分离单体egcg的方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101225082B (zh) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012079916A1 (en) | 2010-12-16 | 2012-06-21 | Unilever Nv | Process for manufacturing a tea product |
CN102526515A (zh) * | 2011-12-08 | 2012-07-04 | 浙江工业大学 | 一种提取竹叶黄酮的方法 |
CN101449805B (zh) * | 2008-12-23 | 2012-08-08 | 浙江工业大学 | 一种从银杏叶中提取银杏提取物的方法 |
CN103380837A (zh) * | 2012-05-06 | 2013-11-06 | 高梦祥 | 茶叶中黄酮类化合物的机械化学提取方法 |
CN104178174A (zh) * | 2014-08-06 | 2014-12-03 | 安徽农业大学 | 一种稳定和提高水性溶液系统中表没食子儿茶素没食子酸酯egcg抗氧化性的方法及其应用 |
CN107495114A (zh) * | 2017-09-11 | 2017-12-22 | 湄潭县君梦食品有限公司 | 一种茶树花面及其加工方法 |
CN109400664A (zh) * | 2018-12-17 | 2019-03-01 | 浙江工业大学 | 一种稻米油植物甾醇的提取方法 |
CN110064223A (zh) * | 2018-01-24 | 2019-07-30 | 绿世纪生物科技股份有限公司 | 茶叶萃取物的制造方法 |
CN114230542A (zh) * | 2021-12-24 | 2022-03-25 | 浙江天草生物科技股份有限公司 | 一种从新鲜茶叶中提取egcg的方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102895388B (zh) * | 2012-09-28 | 2015-01-21 | 桂林益元素生物科技有限公司 | 荔枝多酚类提取物及其提取方法 |
-
2008
- 2008-01-31 CN CN2008100595670A patent/CN101225082B/zh not_active Expired - Fee Related
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101449805B (zh) * | 2008-12-23 | 2012-08-08 | 浙江工业大学 | 一种从银杏叶中提取银杏提取物的方法 |
WO2012079916A1 (en) | 2010-12-16 | 2012-06-21 | Unilever Nv | Process for manufacturing a tea product |
CN102526515A (zh) * | 2011-12-08 | 2012-07-04 | 浙江工业大学 | 一种提取竹叶黄酮的方法 |
CN102526515B (zh) * | 2011-12-08 | 2013-11-13 | 浙江工业大学 | 一种提取竹叶黄酮的方法 |
CN103380837A (zh) * | 2012-05-06 | 2013-11-06 | 高梦祥 | 茶叶中黄酮类化合物的机械化学提取方法 |
CN104178174A (zh) * | 2014-08-06 | 2014-12-03 | 安徽农业大学 | 一种稳定和提高水性溶液系统中表没食子儿茶素没食子酸酯egcg抗氧化性的方法及其应用 |
CN107495114A (zh) * | 2017-09-11 | 2017-12-22 | 湄潭县君梦食品有限公司 | 一种茶树花面及其加工方法 |
CN110064223A (zh) * | 2018-01-24 | 2019-07-30 | 绿世纪生物科技股份有限公司 | 茶叶萃取物的制造方法 |
US11020446B2 (en) | 2018-01-24 | 2021-06-01 | Greenepic Biotech Corporation | Method for preparing tea leaf extract |
CN110064223B (zh) * | 2018-01-24 | 2021-11-19 | 绿世纪生物科技股份有限公司 | 茶叶萃取物的制造方法 |
CN109400664A (zh) * | 2018-12-17 | 2019-03-01 | 浙江工业大学 | 一种稻米油植物甾醇的提取方法 |
CN114230542A (zh) * | 2021-12-24 | 2022-03-25 | 浙江天草生物科技股份有限公司 | 一种从新鲜茶叶中提取egcg的方法 |
WO2023116209A1 (zh) * | 2021-12-24 | 2023-06-29 | 浙江天草生物科技股份有限公司 | 一种从新鲜茶叶中提取egcg的方法 |
Also Published As
Publication number | Publication date |
---|---|
CN101225082B (zh) | 2010-12-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101225082B (zh) | 一种从茶叶中提取茶多酚和分离单体egcg的方法 | |
CN102093369B (zh) | 一种从蚕砂中提取叶绿素并制备铁叶绿酸钠的方法 | |
CN102702163B (zh) | 从茶叶加工下脚料中制备高纯度单体儿茶素的方法 | |
CN102040610A (zh) | 一种利用机械化学原理同时从茶叶中提取咖啡因、茶多酚和茶多糖的新方法 | |
CN101747394B (zh) | 一种从陈皮中提取橙皮苷的方法 | |
CN101716199B (zh) | 一种从木芙蓉叶中提取黄酮类化合物的方法 | |
CN104069059B (zh) | 一种海藻提取液及其制备方法和应用 | |
CN102526515B (zh) | 一种提取竹叶黄酮的方法 | |
CN101638407A (zh) | 一种从茶叶中提取茶多酚的新方法 | |
CN103494862B (zh) | 从油橄榄加工废液中提取橄榄多酚的方法 | |
CN104926680A (zh) | 从低档茶叶及制茶下脚料中提取生物活性物质的方法 | |
CN102961412A (zh) | 一种强化植物天然活性成分提取的球磨耦合浸提集成工艺 | |
CN102850414A (zh) | 从亚麻籽皮中连续提取亚麻胶和木酚素的方法 | |
CN103193832A (zh) | 一种从茶叶中提取分离高纯度茶多酚的方法 | |
CN102863477A (zh) | 利用离子液体从山核桃壳中提取植物多酚的方法 | |
CN101449805B (zh) | 一种从银杏叶中提取银杏提取物的方法 | |
CN110721207A (zh) | 一种从沙棘废渣中提取黄酮类化合物的方法 | |
CN102453107A (zh) | 从柑桔皮制备果胶的方法 | |
CN100582102C (zh) | 从茶叶中制备甲基化儿茶素的工艺方法 | |
CN101759532B (zh) | 一种从厚朴中提取厚朴酚与和厚朴酚的方法 | |
CN101874529A (zh) | 一种山茶籽榨渣二次压榨取油的方法 | |
CN106865853A (zh) | 一种分离含酚废水中酚类化合物的方法 | |
CN103980099B (zh) | 一种从石斛中提取毛兰素的方法 | |
CN103254165A (zh) | 一种白术内酯ii的制备方法 | |
CN101773528B (zh) | 一种低酚酸银杏总内酯的制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Zhejiang Suichang Limin Pharmaceutical Co.,Ltd. Assignor: Zhejiang University of Technology Contract record no.: 2011330001097 Denomination of invention: Method for extracting tea-polyphenol and separating monomer EGCG from tea Granted publication date: 20101201 License type: Exclusive License Open date: 20080723 Record date: 20110822 |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20101201 Termination date: 20150131 |
|
EXPY | Termination of patent right or utility model |