CN101206218B - 血细胞分析装置 - Google Patents

血细胞分析装置 Download PDF

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Publication number
CN101206218B
CN101206218B CN2007103018327A CN200710301832A CN101206218B CN 101206218 B CN101206218 B CN 101206218B CN 2007103018327 A CN2007103018327 A CN 2007103018327A CN 200710301832 A CN200710301832 A CN 200710301832A CN 101206218 B CN101206218 B CN 101206218B
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blood cell
light intensity
scattered light
detecting device
histogram
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Chinese (zh)
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CN101206218A (zh
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乔林森
汉斯卡尔克曼
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Sysmex Corp
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Sysmex Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
CN2007103018327A 2006-12-20 2007-12-18 血细胞分析装置 Active CN101206218B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2006342228 2006-12-20
JP2006342228 2006-12-20
JP2006-342228 2006-12-20

Publications (2)

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CN101206218A CN101206218A (zh) 2008-06-25
CN101206218B true CN101206218B (zh) 2011-12-07

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CN2007103018327A Active CN101206218B (zh) 2006-12-20 2007-12-18 血细胞分析装置

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US (1) US8017078B2 (enExample)
EP (1) EP1936352B1 (enExample)
JP (1) JP5010443B2 (enExample)
CN (1) CN101206218B (enExample)

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* Cited by examiner, † Cited by third party
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US9322834B2 (en) * 2007-05-30 2016-04-26 Sysmex Corporation Sample analyzer, blood analyzer and displaying method
JP5350611B2 (ja) * 2007-06-28 2013-11-27 シスメックス株式会社 表示方法および試料分析装置
JP5530691B2 (ja) * 2009-09-25 2014-06-25 シスメックス株式会社 血球計数装置、診断支援装置、診断支援方法及びコンピュータプログラム
US8964171B2 (en) 2011-07-22 2015-02-24 Roche Diagnostics Hematology, Inc. Identifying and measuring reticulocytes
CN103090886B (zh) * 2011-10-31 2015-08-26 深圳迈瑞生物医疗电子股份有限公司 光信号的去噪方法和装置
US9939453B2 (en) 2012-12-31 2018-04-10 Beckman Coulter, Inc. Immature platelet enumeration systems and methods
JP6612050B2 (ja) 2014-08-28 2019-11-27 シスメックス株式会社 血液分析装置、診断支援方法、およびコンピュータプログラム
JP6370659B2 (ja) * 2014-09-26 2018-08-08 シスメックス株式会社 血液分析装置および血液分析方法
CN108463722B (zh) * 2016-03-30 2021-09-21 西门子医疗保健诊断公司 用于处理血小板细胞数据的系统、方法和设备
US11226278B2 (en) 2016-11-08 2022-01-18 Kennesaw State University Research And Service Foundation, Inc. Leukocyte quantitation microfluidic method and device
CN108169081B (zh) * 2017-12-14 2021-06-04 四川大学华西医院 血细胞分析的差值核查方法及其应用方法
CN108416767B (zh) * 2018-02-09 2021-02-19 重庆东渝中能实业有限公司 基于全息成像的红细胞多项生理参数检测方法
CN113015903B (zh) * 2019-06-11 2024-05-14 深圳迈瑞生物医疗电子股份有限公司 样本检测方法及样本分析仪
JP7491703B2 (ja) * 2020-02-05 2024-05-28 日本光電工業株式会社 粒子分析方法および粒子分析装置
WO2021179177A1 (zh) * 2020-03-10 2021-09-16 深圳迈瑞生物医疗电子股份有限公司 血液分析仪、血液分析方法和计算机可读存储介质
EP3905260A1 (en) * 2020-04-28 2021-11-03 Sysmex Corporation Method, apparatus and system for testing blood
CN114252384B (zh) * 2021-12-02 2022-12-13 中元汇吉生物技术股份有限公司 网织红细胞计数方法、装置、系统与计算机可读存储介质
CN114813706B (zh) * 2022-06-29 2022-12-13 国科大杭州高等研究院 一种血细胞高光谱光镊捕获能量共振转移分析仪

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525807B1 (en) * 1999-01-21 2003-02-25 Sysmex Corporation Particle analyzing apparatus
US6535836B1 (en) * 2000-09-29 2003-03-18 Coulter International Corp. Method for the analysis of abnormal particle populations

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Publication number Priority date Publication date Assignee Title
JPS5825144A (ja) * 1981-08-07 1983-02-15 東亜医用電子株式会社 血液分析方法およびその装置
JPS5858439A (ja) * 1981-10-01 1983-04-07 Toa Medical Electronics Co Ltd 血小板計数装置
JPS59184841A (ja) * 1983-04-05 1984-10-20 ベクトン・デイツキンソン・アンド・カンパニ− サンプル中の白血球のサブクラスを識別する方法および装置
US4735504A (en) * 1983-10-31 1988-04-05 Technicon Instruments Corporation Method and apparatus for determining the volume & index of refraction of particles
JPS61225656A (ja) * 1985-03-29 1986-10-07 Toshiba Corp 検体検査装置
US4704891A (en) * 1986-08-29 1987-11-10 Becton, Dickinson And Company Method and materials for calibrating flow cytometers and other analysis instruments
JP2674705B2 (ja) * 1988-06-10 1997-11-12 東亜医用電子株式会社 一次元分布分画方法
JP2815435B2 (ja) * 1989-12-22 1998-10-27 株式会社日立製作所 粒子解析装置及び血球カウンタ
US5194909A (en) * 1990-12-04 1993-03-16 Tycko Daniel H Apparatus and method for measuring volume and hemoglobin concentration of red blood cells
JP3232145B2 (ja) * 1991-12-27 2001-11-26 シスメックス株式会社 網赤血球測定方法
US5844685A (en) * 1996-07-30 1998-12-01 Bayer Corporation Reference laser beam sampling apparatus
JP3867880B2 (ja) * 1998-04-08 2007-01-17 シスメックス株式会社 尿中赤血球の鑑別装置および方法
US6592822B1 (en) * 1998-05-14 2003-07-15 Luminex Corporation Multi-analyte diagnostic system and computer implemented process for same
JPH11326315A (ja) * 1998-05-21 1999-11-26 Sysmex Corp β−サラセミアの鑑別方法
US6630990B2 (en) * 2001-06-05 2003-10-07 Abbott Laboratories Optical method and apparatus for red blood cell differentiation on a cell-by-cell basis, and simultaneous analysis of white blood cell differentiation
JP4417143B2 (ja) * 2004-03-11 2010-02-17 シスメックス株式会社 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体
JP4679843B2 (ja) * 2004-07-02 2011-05-11 シスメックス株式会社 血液分析装置および分析プログラム

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525807B1 (en) * 1999-01-21 2003-02-25 Sysmex Corporation Particle analyzing apparatus
US6535836B1 (en) * 2000-09-29 2003-03-18 Coulter International Corp. Method for the analysis of abnormal particle populations

Also Published As

Publication number Publication date
EP1936352A3 (en) 2013-02-27
EP1936352B1 (en) 2015-08-12
EP1936352A2 (en) 2008-06-25
CN101206218A (zh) 2008-06-25
US20080199947A1 (en) 2008-08-21
US8017078B2 (en) 2011-09-13
JP2008175807A (ja) 2008-07-31
JP5010443B2 (ja) 2012-08-29

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