CN101106996B - 羟考酮用于治疗内脏痛的用途 - Google Patents

羟考酮用于治疗内脏痛的用途 Download PDF

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Publication number
CN101106996B
CN101106996B CN2006800024739A CN200680002473A CN101106996B CN 101106996 B CN101106996 B CN 101106996B CN 2006800024739 A CN2006800024739 A CN 2006800024739A CN 200680002473 A CN200680002473 A CN 200680002473A CN 101106996 B CN101106996 B CN 101106996B
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CN
China
Prior art keywords
oxycodone
pharmaceutically acceptable
morphine
acceptable salt
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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CN2006800024739A
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English (en)
Chinese (zh)
Other versions
CN101106996A (zh
Inventor
阿斯比约恩·莫尔·德勒韦斯
拉尔斯·阿伦特·尼尔森
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Euro Celtique SA
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Euro Celtique SA
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Publication of CN101106996A publication Critical patent/CN101106996A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2006800024739A 2005-01-18 2006-01-17 羟考酮用于治疗内脏痛的用途 Expired - Lifetime CN101106996B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64549005P 2005-01-18 2005-01-18
US60/645,490 2005-01-18
PCT/EP2006/050252 WO2006077212A1 (en) 2005-01-18 2006-01-17 Use of oxycodone for treating visceral pain

Publications (2)

Publication Number Publication Date
CN101106996A CN101106996A (zh) 2008-01-16
CN101106996B true CN101106996B (zh) 2013-10-23

Family

ID=35871217

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2006800024739A Expired - Lifetime CN101106996B (zh) 2005-01-18 2006-01-17 羟考酮用于治疗内脏痛的用途

Country Status (31)

Country Link
US (2) US20080200493A1 (https=)
EP (1) EP1838318B1 (https=)
JP (1) JP5049139B2 (https=)
KR (10) KR20230170811A (https=)
CN (1) CN101106996B (https=)
AP (1) AP2249A (https=)
AR (1) AR052880A1 (https=)
AT (2) ATE446092T1 (https=)
AU (1) AU2006207498B2 (https=)
BR (1) BRPI0606247A2 (https=)
CA (1) CA2595043C (https=)
CY (1) CY1109660T1 (https=)
DE (2) DE602006009899D1 (https=)
DK (2) DK1838318T3 (https=)
EA (1) EA013544B1 (https=)
ES (1) ES2333901T3 (https=)
HR (1) HRP20090679T1 (https=)
IL (1) IL184530A (https=)
ME (1) ME01066B (https=)
MX (1) MX2007007207A (https=)
MY (1) MY144471A (https=)
NO (1) NO338968B1 (https=)
NZ (1) NZ555852A (https=)
PL (1) PL1838318T3 (https=)
PT (1) PT1838318E (https=)
RS (1) RS51069B (https=)
SI (1) SI1838318T1 (https=)
TW (1) TWI432196B (https=)
UA (1) UA85471C2 (https=)
WO (1) WO2006077212A1 (https=)
ZA (1) ZA200705231B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3069731A1 (en) 2005-11-14 2016-09-21 Labrys Biologics Inc. Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
EP2155167A2 (en) 2007-06-04 2010-02-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
RU2522493C2 (ru) 2008-03-04 2014-07-20 Пфайзер Лимитед Способы лечения хронической боли
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
CN102740884A (zh) 2009-08-28 2012-10-17 瑞纳神经科学公司 通过施用针对降钙素基因相关肽的拮抗性抗体来治疗内脏痛的方法
PE20141787A1 (es) 2011-05-20 2014-12-07 Alderbio Holdings Llc Composiciones anti-cgrp y uso de las mismas
TWI705825B (zh) 2011-05-20 2020-10-01 美商艾爾德生物控股有限責任公司 抗降血鈣素基因相關胜肽（ａｎｔｉ－ｃｇｒｐ）或抗降血鈣素基因相關胜肽受器（ａｎｔｉ－ｃｇｒｐ－ｒ）抗體或抗體片段治療或預防慢性及急性型腹瀉之用途
CN107827982B (zh) 2011-05-20 2021-07-06 H.伦德贝克公司 抗cgrp抗体和抗体片段用于在有需要的受试者中预防或抑制畏光或厌光的用途
US20170114122A1 (en) 2015-10-23 2017-04-27 Alderbio Holdings Llc Regulation of glucose metabolism using anti-cgrp antibodies
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
AU2015230933B2 (en) 2014-03-21 2020-08-13 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
CN109952314A (zh) 2016-09-23 2019-06-28 泰瓦制药国际有限公司 治疗难治性偏头痛
CA3115122A1 (en) 2018-11-19 2020-05-28 Jazz Pharmaceuticals Ireland Limited Alcohol-resistant drug formulations
WO2020146527A1 (en) 2019-01-08 2020-07-16 Alder Biopharmaceuticals, Inc. Acute treatment and rapid treatment of headache using anti-cgrp antibodies
CA3077973A1 (en) 2020-04-06 2021-10-06 H. Lundbeck A/S Treatment of most bothersome symptom (mbs) associated with migraine using anti-cgrp antibodies

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656295A (en) * 1991-11-27 1997-08-12 Euro-Celtique, S.A. Controlled release oxycodone compositions
US5945416A (en) * 1996-03-25 1999-08-31 Eli Lilly And Company Method for treating pain
CN1514721A (zh) * 2001-05-02 2004-07-21 ŷ�����ǹɷ����޹�˾ 一日服用一次的羟考酮制剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US6992193B2 (en) * 2003-06-10 2006-01-31 Adolor Corporation Sulfonylamino phenylacetamide derivatives and methods of their use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656295A (en) * 1991-11-27 1997-08-12 Euro-Celtique, S.A. Controlled release oxycodone compositions
US5945416A (en) * 1996-03-25 1999-08-31 Eli Lilly And Company Method for treating pain
CN1514721A (zh) * 2001-05-02 2004-07-21 ŷ�����ǹɷ����޹�˾ 一日服用一次的羟考酮制剂

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GR Lauretti et al.Comparison of sustained-release morphine with sustained-release oxycodone in advanced cancer patients.British journal of ancer89 11.2003,89(11),第2027页右栏第1段,第2028页左栏第6-10行,第24-26行. *
Nathalie Do Quang-Cantagrel et al.Opioid substitution to improve the effectiveness ofchronicnancancer pain control:achart review.Anesthesia & Analgesia90.2000,90第933-937页. *

Also Published As

Publication number Publication date
CA2595043A1 (en) 2006-07-27
PT1838318E (pt) 2009-12-15
KR20120089710A (ko) 2012-08-13
MY144471A (en) 2011-09-30
KR20070100368A (ko) 2007-10-10
KR20140091782A (ko) 2014-07-22
AU2006207498B2 (en) 2009-11-19
DE202006019887U1 (de) 2007-07-26
ES2333901T3 (es) 2010-03-02
IL184530A (en) 2015-01-29
KR20170021905A (ko) 2017-02-28
MX2007007207A (es) 2007-08-15
US20150190393A1 (en) 2015-07-09
KR20200128451A (ko) 2020-11-12
NZ555852A (en) 2010-01-29
ATE446092T1 (de) 2009-11-15
CY1109660T1 (el) 2014-08-13
PL1838318T3 (pl) 2010-03-31
SI1838318T1 (sl) 2010-02-26
AU2006207498A1 (en) 2006-07-27
EA200701541A1 (ru) 2008-02-28
KR20190135557A (ko) 2019-12-06
KR20220165797A (ko) 2022-12-15
EP1838318B1 (en) 2009-10-21
AP2249A (en) 2011-07-18
DK200700207U3 (da) 2007-09-28
IL184530A0 (en) 2007-10-31
NO20074174L (no) 2007-10-17
AP2007004057A0 (en) 2007-08-31
JP5049139B2 (ja) 2012-10-17
KR20080106991A (ko) 2008-12-09
US20080200493A1 (en) 2008-08-21
EP1838318A1 (en) 2007-10-03
BRPI0606247A2 (pt) 2009-06-09
DK1838318T3 (da) 2010-01-04
AT9895U1 (de) 2008-05-15
AR052880A1 (es) 2007-04-11
ZA200705231B (en) 2008-06-25
WO2006077212A1 (en) 2006-07-27
DK200700207U1 (da) 2007-08-24
DE602006009899D1 (de) 2009-12-03
JP2008526927A (ja) 2008-07-24
KR20210131450A (ko) 2021-11-02
HRP20090679T1 (hr) 2010-01-31
CA2595043C (en) 2013-11-19
TW200637554A (en) 2006-11-01
KR20230170811A (ko) 2023-12-19
HK1107933A1 (en) 2008-04-25
NO338968B1 (no) 2016-11-07
RS51069B (sr) 2010-10-31
UA85471C2 (ru) 2009-01-26
CN101106996A (zh) 2008-01-16
ME01066B (me) 2012-10-20
US9271974B2 (en) 2016-03-01
EA013544B1 (ru) 2010-06-30
TWI432196B (zh) 2014-04-01

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