CN101106996B - 羟考酮用于治疗内脏痛的用途 - Google Patents

羟考酮用于治疗内脏痛的用途 Download PDF

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Publication number
CN101106996B
CN101106996B CN2006800024739A CN200680002473A CN101106996B CN 101106996 B CN101106996 B CN 101106996B CN 2006800024739 A CN2006800024739 A CN 2006800024739A CN 200680002473 A CN200680002473 A CN 200680002473A CN 101106996 B CN101106996 B CN 101106996B
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China
Prior art keywords
oxycodone
pain
pharmaceutically acceptable
morphine
salt
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CN2006800024739A
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English (en)
Chinese (zh)
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CN101106996A (zh
Inventor
阿斯比约恩·莫尔·德勒韦斯
拉尔斯·阿伦特·尼尔森
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Euro Celtique SA
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Euro Celtique SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2006800024739A 2005-01-18 2006-01-17 羟考酮用于治疗内脏痛的用途 Active CN101106996B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64549005P 2005-01-18 2005-01-18
US60/645,490 2005-01-18
PCT/EP2006/050252 WO2006077212A1 (en) 2005-01-18 2006-01-17 Use of oxycodone for treating visceral pain

Publications (2)

Publication Number Publication Date
CN101106996A CN101106996A (zh) 2008-01-16
CN101106996B true CN101106996B (zh) 2013-10-23

Family

ID=35871217

Family Applications (1)

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CN2006800024739A Active CN101106996B (zh) 2005-01-18 2006-01-17 羟考酮用于治疗内脏痛的用途

Country Status (31)

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US (2) US20080200493A1 (enExample)
EP (1) EP1838318B1 (enExample)
JP (1) JP5049139B2 (enExample)
KR (10) KR20200128451A (enExample)
CN (1) CN101106996B (enExample)
AP (1) AP2249A (enExample)
AR (1) AR052880A1 (enExample)
AT (2) ATE446092T1 (enExample)
AU (1) AU2006207498B2 (enExample)
BR (1) BRPI0606247A2 (enExample)
CA (1) CA2595043C (enExample)
CY (1) CY1109660T1 (enExample)
DE (2) DE602006009899D1 (enExample)
DK (2) DK1838318T3 (enExample)
EA (1) EA013544B1 (enExample)
ES (1) ES2333901T3 (enExample)
HR (1) HRP20090679T1 (enExample)
IL (1) IL184530A (enExample)
ME (1) ME01066B (enExample)
MX (1) MX2007007207A (enExample)
MY (1) MY144471A (enExample)
NO (1) NO338968B1 (enExample)
NZ (1) NZ555852A (enExample)
PL (1) PL1838318T3 (enExample)
PT (1) PT1838318E (enExample)
RS (1) RS51069B (enExample)
SI (1) SI1838318T1 (enExample)
TW (1) TWI432196B (enExample)
UA (1) UA85471C2 (enExample)
WO (1) WO2006077212A1 (enExample)
ZA (1) ZA200705231B (enExample)

Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
DK3045182T3 (en) 2005-11-14 2018-03-19 Teva Pharmaceuticals Int Gmbh ANTAGONIST ANTIBODIES AGAINST CALCITONIN GEN-RELATED PEPTIDE TO TREAT HEAT
WO2008148798A2 (en) 2007-06-04 2008-12-11 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
WO2009109911A1 (en) 2008-03-04 2009-09-11 Pfizer Limited Methods of treating chronic pain
CA2751667C (en) 2009-02-06 2016-12-13 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
EP2445487A2 (en) 2009-06-24 2012-05-02 Egalet Ltd. Controlled release formulations
RU2535074C2 (ru) * 2009-08-28 2014-12-10 Лэйбрис Байолоджикс, Инк. Способы лечения висцеральной боли путем введения антител-антагонистов, направленных против пептида, связанного с геном кальцитонина
TWI692485B (zh) 2011-05-20 2020-05-01 美商艾爾德生物控股有限責任公司 抗降血鈣素基因相關胜肽（ａｎｔｉ-ｃｇｒｐ）組成物及其用途
CN103702685B (zh) 2011-05-20 2017-12-15 奥尔德生物控股有限责任公司 抗cgrp抗体和抗体片段用于在有需要的受试者、尤其是偏头痛患者中预防或抑制畏光或厌光的用途
KR102128628B1 (ko) 2011-05-20 2020-06-30 앨더바이오 홀딩스 엘엘씨 설사의 만성 및 급성 형태를 치료 또는 예방하기 위한 항-cgrp 또는 항-cgrp-r 항체 또는 항체 단편의 용도
US20170114122A1 (en) 2015-10-23 2017-04-27 Alderbio Holdings Llc Regulation of glucose metabolism using anti-cgrp antibodies
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
RS65360B1 (sr) 2014-03-21 2024-04-30 Teva Pharmaceuticals Int Gmbh Antagonistička antitela specifična za peptid genski srodan kalcitoninu i postupci njihove upotrebe
AU2017331593B2 (en) 2016-09-23 2022-04-28 Teva Pharmaceuticals International Gmbh Treating refractory migraine
JP7472116B2 (ja) 2018-11-19 2024-04-22 ジャズ ファーマシューティカルズ アイルランド リミテッド 耐アルコール性製剤
US11639380B2 (en) 2019-01-08 2023-05-02 H. Lundbeck A/S Acute treatment and rapid treatment of headache using anti-CGRP antibodies
SG10202003296VA (en) 2020-04-06 2021-11-29 H Lundbeck As Treatment of most bothersome symptom (mbs) associated with migraine using anti-cgrp antibodies

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656295A (en) * 1991-11-27 1997-08-12 Euro-Celtique, S.A. Controlled release oxycodone compositions
US5945416A (en) * 1996-03-25 1999-08-31 Eli Lilly And Company Method for treating pain
CN1514721A (zh) * 2001-05-02 2004-07-21 ŷ�����ǹɷ����޹�˾ 一日服用一次的羟考酮制剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
US6992193B2 (en) * 2003-06-10 2006-01-31 Adolor Corporation Sulfonylamino phenylacetamide derivatives and methods of their use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656295A (en) * 1991-11-27 1997-08-12 Euro-Celtique, S.A. Controlled release oxycodone compositions
US5945416A (en) * 1996-03-25 1999-08-31 Eli Lilly And Company Method for treating pain
CN1514721A (zh) * 2001-05-02 2004-07-21 ŷ�����ǹɷ����޹�˾ 一日服用一次的羟考酮制剂

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GR Lauretti et al.Comparison of sustained-release morphine with sustained-release oxycodone in advanced cancer patients.British journal of ancer89 11.2003,89(11),第2027页右栏第1段,第2028页左栏第6-10行,第24-26行. *
Nathalie Do Quang-Cantagrel et al.Opioid substitution to improve the effectiveness ofchronicnancancer pain control:achart review.Anesthesia & Analgesia90.2000,90第933-937页. *

Also Published As

Publication number Publication date
RS51069B (sr) 2010-10-31
KR20200128451A (ko) 2020-11-12
DK200700207U3 (da) 2007-09-28
KR20120089710A (ko) 2012-08-13
HK1107933A1 (en) 2008-04-25
UA85471C2 (ru) 2009-01-26
CA2595043C (en) 2013-11-19
MY144471A (en) 2011-09-30
DK200700207U1 (da) 2007-08-24
DK1838318T3 (da) 2010-01-04
US20080200493A1 (en) 2008-08-21
KR20230170811A (ko) 2023-12-19
NO338968B1 (no) 2016-11-07
ATE446092T1 (de) 2009-11-15
US9271974B2 (en) 2016-03-01
NO20074174L (no) 2007-10-17
ES2333901T3 (es) 2010-03-02
KR20070100368A (ko) 2007-10-10
PT1838318E (pt) 2009-12-15
EP1838318B1 (en) 2009-10-21
US20150190393A1 (en) 2015-07-09
DE602006009899D1 (de) 2009-12-03
SI1838318T1 (sl) 2010-02-26
ME01066B (me) 2012-10-20
IL184530A0 (en) 2007-10-31
KR20170021905A (ko) 2017-02-28
MX2007007207A (es) 2007-08-15
NZ555852A (en) 2010-01-29
TWI432196B (zh) 2014-04-01
EA200701541A1 (ru) 2008-02-28
HRP20090679T1 (hr) 2010-01-31
AP2007004057A0 (en) 2007-08-31
AT9895U1 (de) 2008-05-15
KR20190135557A (ko) 2019-12-06
CA2595043A1 (en) 2006-07-27
EP1838318A1 (en) 2007-10-03
CY1109660T1 (el) 2014-08-13
KR20080106991A (ko) 2008-12-09
WO2006077212A1 (en) 2006-07-27
AU2006207498A1 (en) 2006-07-27
AP2249A (en) 2011-07-18
DE202006019887U1 (de) 2007-07-26
IL184530A (en) 2015-01-29
AR052880A1 (es) 2007-04-11
CN101106996A (zh) 2008-01-16
JP2008526927A (ja) 2008-07-24
BRPI0606247A2 (pt) 2009-06-09
AU2006207498B2 (en) 2009-11-19
JP5049139B2 (ja) 2012-10-17
PL1838318T3 (pl) 2010-03-31
ZA200705231B (en) 2008-06-25
KR20220165797A (ko) 2022-12-15
KR20140091782A (ko) 2014-07-22
TW200637554A (en) 2006-11-01
KR20210131450A (ko) 2021-11-02
EA013544B1 (ru) 2010-06-30

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