CN101095855A - Chinese traditional medicine preparations for treating anaphylactoid purpura nephritis - Google Patents
Chinese traditional medicine preparations for treating anaphylactoid purpura nephritis Download PDFInfo
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- CN101095855A CN101095855A CNA2007101183279A CN200710118327A CN101095855A CN 101095855 A CN101095855 A CN 101095855A CN A2007101183279 A CNA2007101183279 A CN A2007101183279A CN 200710118327 A CN200710118327 A CN 200710118327A CN 101095855 A CN101095855 A CN 101095855A
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Abstract
The invention relates to a Chinese medicinal preparation for treating allergic purpura nephritis, which is prepared from more than ten kinds of Chinese medicinal herbs including anemarrhena rhizome, cogongrass rhizome, ligustrum japonicum and arborvitae tops. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to treat the Chinese medicine preparation of anaphy lactoid purpura nephritis, is that a kind of anaphy lactoid purpura nephritis for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Anaphylactoid purpura is to be the syndrome of feature with skin purpura, gastroenteritis haemorrhagica, arthritis and kidney damage, is a kind of general polyangitis relevant with immunity.The renal damage that anaphylactoid purpura causes claims anaphy lactoid purpura nephritis.The clinical symptoms weight differs, from simple urine examination unusually to the typical acute nephritic syndrome, nephrotic syndrome even renal failure.Hematuria (under naked eyes or the mirror) is its common performance, and Most patients is optimum, self-limited course is more than fully recovering in several weeks.But outbreak repeatedly or delay several months, several years person are arranged also.About 50% patient's course of disease is shown effect repeatedly.The order of severity of pathological change is depended in prognosis.The anaphy lactoid purpura nephritis sickness rate accounts for 20%～100% of patients with anaphylactoid purpura, domesticly is reported in 30%～50%, abroad have with the kidney biopsy be diagnostic criteria then sickness rate up to more than 90%.Any age of primary disease all can fall ill, and is more common in child and teenager, with 6～13 years old for the highest, gender's ratio is 1.5～3: 1, betides cold season well.Henoch Schonlein purpura nephritis belongs to Chinese medicine " hematuria ", " hematohidrosis ", " edema " sick categories such as " arthromyodynias ".The clinical manifestation of primary disease is: erythra, joint symptom, gastrointestinal symptom and other symptom.
The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as pathogenic wind toxic is invaded, the high Sheng of pyretic toxicity, the heat in blood of suffering from a deficiency of the kidney, asthenia of pulmonosplenic qi, deficiency of both QI and YIN, deficiency of spleen-YANG and kidneyYANG clinically outward, obtains very good effect.The traditional Chinese medical science and therapy of combining Chinese and Western medicine henoch Schonlein purpura nephritis have been received curative effect preferably in recent years, have represented fine prospect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide the Chinese medicine preparation for the treatment of anaphy lactoid purpura nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Rhizoma Imperataes of 1.5～6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae
1.0～4 parts of 1.0～4 portions of Cacumen Platycladis of 1.0～4 portions of Rhizoma Dioscoreaes of Fructus Ligustri Lucidi
1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 parts of Carapax Trionycis of Poria
0.1～2 part of 0.1～2 portion of Radix Arnebiae (Radix Lithospermi) of 0.1～2 portion of Cortex Phellodendri of Fructus Corni.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Imperataes of 2.5～3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae
1.5～2.5 parts of 1.5～2.5 portions of Cacumen Platycladis of 1.5～2.5 portions of Rhizoma Dioscoreaes of Fructus Ligustri Lucidi
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 parts of Carapax Trionycis of Poria
0.5～1.5 part of 0.5～1.5 portion of Radix Arnebiae (Radix Lithospermi) of 0.5～1.5 portion of Cortex Phellodendri of Fructus Corni.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Rhizoma Imperataes of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae
2 parts of 2 portions of Cacumen Platycladis of 2 portions of Rhizoma Dioscoreaes of Fructus Ligustri Lucidi
2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Carapax Trionycis of Poria
1 part of 1 portion of Radix Arnebiae (Radix Lithospermi) of 1 portion of Cortex Phellodendri of Fructus Corni.
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Rhizoma Anemarrhenae property of medicine hardship, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, nourishing yin and moistening dryness.Can treat epidemic febrile disease hyperpyrexia excessive thirst, the cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia is quenched one's thirst etc.(the 1924th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Imperatae property of medicine is sweet, and is cold.GUIXIN, lung, stomach, urinary bladder channel.Has clearing away heat and promoting production of body fluid, cooling blood for hemostasis, the effect of inducing diuresis for treating stranguria syndrome.Can treat the calentura excessive thirst, dyspnea and cough due to lung-heat, the gastric heat vomiting, heat in blood is hemorrhage, the puckery pain of dribbling urination, edema, jaundice etc.(the 992nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Ligustri Lucidi property of medicine is sweet, bitter, cold.Return liver, kidney channel.Has liver and kidney tonifying, clearind deficient heat, the effect that makes eye bright.Can treat Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision etc.(the 324th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cacumen Platycladi property of medicine hardship, puckery is slightly cold.Return lung, liver, large intestine channel.Has cooling blood for hemostasis, expelling phlegm for arresting cough, the antidotal effect of dispeling the wind.Can treat haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, cough with copious phlegm, rheumatic arthralgia, alopecia, erysipelas, mumps is scalded etc.(the 1934th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Carapax Trionycis property of medicine is salty, is slightly cold.Return liver, kidney channel.Has nourishing YIN and clearing away heat, suppressing hyper-yang to eliminate wind, the effect of hard masses softening and resolving.Can treat fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, consumption of YIN caused by febrile disease, stirring-up of pathogenic wind in the interior resulting from deficiency, pediatric epilepsy scared, chronic malaria, malaria with splenomegaly ， mass in the abdomen, amenorrhea etc.(the 3369th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Phellodendri property of medicine hardship, cold.Return kidney, bladder, large intestine channel.Has heat clearing and damp drying, the effect of eliminating fire and detoxication.Can treat hygropyretic dysentery, have loose bowels, jaundice, nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever ， Wei Bi, and aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema etc.(the 2823rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Arnebiae (Radix Lithospermi) property of medicine hardship, cold.GUIXIN, Liver Channel.Has removing heat from blood and promoting blood circulation, the effect of detoxifcation rash.Can treat haematemesis, epistaxis, hematuria, purpura, macule, measles, jaundice, carbuncle is scalded etc.(the 3272nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, the Rhizoma Anemarrhenae and Rhizoma Imperatae; With Fructus Ligustri Lucidi, Fructus Corni, Rhizoma Dioscoreae, Poria, Carapax Trionycis, Cacumen Platycladi and Rhizoma Alismatis is ministerial drug; With Cortex Phellodendri and Radix Arnebiae (Radix Lithospermi) is adjuvant.All medicines are harmonious, tool enriching yin and nourishing kidney altogether, the effect of cooling blood for hemostasis.The treatment anaphy lactoid purpura nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment anaphy lactoid purpura nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat anaphy lactoid purpura nephritis, and the prevention of anaphy lactoid purpura nephritis is also had good effect, and the treatment anaphy lactoid purpura nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment anaphy lactoid purpura nephritis; Treatment anaphy lactoid purpura nephritis patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 44.44%, and 6 examples that take a turn for the better account for 33.33%, and invalid 4 examples account for 22.22%, and total effective rate reaches 77.77%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Rhizoma Imperataes of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae
2 parts of 2 portions of Cacumen Platycladis of 2 portions of Rhizoma Dioscoreaes of Fructus Ligustri Lucidi
2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Carapax Trionycis of Poria
1 part of 1 portion of Radix Arnebiae (Radix Lithospermi) of 1 portion of Cortex Phellodendri of Fructus Corni.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment anaphy lactoid purpura nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, the Chinese medicine preparation of treatment anaphy lactoid purpura nephritis is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Rhizoma Imperataes of 1.5～6 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae
1.0～4 parts of 1.0～4 portions of Cacumen Platycladis of 1.0～4 portions of Rhizoma Dioscoreaes of Fructus Ligustri Lucidi
1.0～4 parts of 1.0～4 portions of Rhizoma Alismatis of 1.0～4 parts of Carapax Trionycis of Poria
0.1～2 part of 0.1～2 portion of Radix Arnebiae (Radix Lithospermi) of 0.1～2 portion of Cortex Phellodendri of Fructus Corni.
2, the Chinese medicine preparation of treatment anaphy lactoid purpura nephritis according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 parts of Rhizoma Imperataes of 2.5～3.5 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae
1.5～2.5 parts of 1.5～2.5 portions of Cacumen Platycladis of 1.5～2.5 portions of Rhizoma Dioscoreaes of Fructus Ligustri Lucidi
1.5～2.5 parts of 1.5～2.5 portions of Rhizoma Alismatis of 1.5～2.5 parts of Carapax Trionycis of Poria
0.5～1.5 part of 0.5～1.5 portion of Radix Arnebiae (Radix Lithospermi) of 0.5～1.5 portion of Cortex Phellodendri of Fructus Corni.
3, the Chinese medicine preparation of treatment anaphy lactoid purpura nephritis according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Rhizoma Imperataes of 3 parts of Rhizoma Anemarrhenaes of Radix Rehmanniae
2 parts of 2 portions of Cacumen Platycladis of 2 portions of Rhizoma Dioscoreaes of Fructus Ligustri Lucidi
2 parts of 2 portions of Rhizoma Alismatis of 2 parts of Carapax Trionycis of Poria
1 part of 1 portion of Radix Arnebiae (Radix Lithospermi) of 1 portion of Cortex Phellodendri of Fructus Corni.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101183279A CN101095855A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating anaphylactoid purpura nephritis |
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| CNA2007101183279A CN101095855A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating anaphylactoid purpura nephritis |
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| CN101095855A true CN101095855A (en) | 2008-01-02 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102580021A (en) * | 2011-11-16 | 2012-07-18 | 姜艳艳 | Turtle cream greenish white soup for primary glomerulonephritis |
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2007
- 2007-07-05 CN CNA2007101183279A patent/CN101095855A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102580021A (en) * | 2011-11-16 | 2012-07-18 | 姜艳艳 | Turtle cream greenish white soup for primary glomerulonephritis |
| CN102580021B (en) * | 2011-11-16 | 2013-07-17 | 姜艳艳 | Turtle cream greenish white soup for primary glomerulonephritis |
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Open date: 20080102 |