CN101048138B - 脂质体糖皮质激素用于治疗炎性状态的用途 - Google Patents

脂质体糖皮质激素用于治疗炎性状态的用途 Download PDF

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CN101048138B
CN101048138B CN2005800359742A CN200580035974A CN101048138B CN 101048138 B CN101048138 B CN 101048138B CN 2005800359742 A CN2005800359742 A CN 2005800359742A CN 200580035974 A CN200580035974 A CN 200580035974A CN 101048138 B CN101048138 B CN 101048138B
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liposome
mps
liposomes
glucocorticoid
prodrug
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Expired - Fee Related
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CN101048138A (zh
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叶切科尔·巴伦霍茨
雅各布·纳帕斯塔克
尤瓦尔·阿夫尼埃尔
里娜·乌尔曼斯基
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Hadasit Medical Research Services and Development Co
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Hadasit Medical Research Services and Development Co
Yissum Research Development Co of Hebrew University of Jerusalem
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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CN2005800359742A 2004-09-09 2005-09-11 脂质体糖皮质激素用于治疗炎性状态的用途 Expired - Fee Related CN101048138B (zh)

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Application Number Priority Date Filing Date Title
US60814004P 2004-09-09 2004-09-09
US60/608,140 2004-09-09
PCT/IL2005/000962 WO2006027786A2 (en) 2004-09-09 2005-09-11 Use of liposomal glucocorticoids for treating inflammatory states

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CN101048138A CN101048138A (zh) 2007-10-03
CN101048138B true CN101048138B (zh) 2010-12-08

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CN2005800359742A Expired - Fee Related CN101048138B (zh) 2004-09-09 2005-09-11 脂质体糖皮质激素用于治疗炎性状态的用途
CN200580035942.2A Expired - Fee Related CN101043875B (zh) 2004-09-09 2005-09-11 糖皮质激素和糖皮质激素衍生物的脂质体组合物

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US (3) US7744920B2 (enExample)
EP (2) EP1793804A2 (enExample)
JP (2) JP5355890B2 (enExample)
CN (2) CN101048138B (enExample)
AU (2) AU2005281352B2 (enExample)
CA (2) CA2579695A1 (enExample)
WO (2) WO2006027786A2 (enExample)

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TWI754659B (zh) * 2016-08-08 2022-02-11 台灣微脂體股份有限公司 用於製備含有弱酸性劑之微脂體組合物的傳輸載體、方法及套組
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TWI755629B (zh) * 2018-09-13 2022-02-21 台灣微脂體股份有限公司 含鎮靜藥物之緩釋藥物組合物及其用途
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CA2579695A1 (en) 2006-03-16
JP5355890B2 (ja) 2013-11-27
WO2006027787A1 (en) 2006-03-16
AU2005281351A1 (en) 2006-03-16
JP2008512445A (ja) 2008-04-24
CN101043875B (zh) 2014-05-07
AU2005281351B2 (en) 2011-02-24
CN101043875A (zh) 2007-09-26
AU2005281352A1 (en) 2006-03-16
US7744920B2 (en) 2010-06-29
EP1793804A2 (en) 2007-06-13
US8932627B2 (en) 2015-01-13
WO2006027786A8 (en) 2006-08-31
WO2006027786A3 (en) 2006-04-27
US20150093434A1 (en) 2015-04-02
EP1791525A1 (en) 2007-06-06
US20080003276A1 (en) 2008-01-03
JP2008512446A (ja) 2008-04-24
US20080058294A1 (en) 2008-03-06
CN101048138A (zh) 2007-10-03
WO2006027786A2 (en) 2006-03-16
CA2579786A1 (en) 2006-03-16
AU2005281352B2 (en) 2011-01-27

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