CN101022789A - 一种药物组合物 - Google Patents

一种药物组合物 Download PDF

Info

Publication number
CN101022789A
CN101022789A CNA2005800222148A CN200580022214A CN101022789A CN 101022789 A CN101022789 A CN 101022789A CN A2005800222148 A CNA2005800222148 A CN A2005800222148A CN 200580022214 A CN200580022214 A CN 200580022214A CN 101022789 A CN101022789 A CN 101022789A
Authority
CN
China
Prior art keywords
ibuprofen
acetaminophen
pharmaceutical composition
dose
paracetamol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005800222148A
Other languages
English (en)
Chinese (zh)
Inventor
哈特利·坎贝尔·阿特金森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Research Centre
Original Assignee
Wockhardt Research Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Research Centre filed Critical Wockhardt Research Centre
Publication of CN101022789A publication Critical patent/CN101022789A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
CNA2005800222148A 2004-07-07 2005-07-07 一种药物组合物 Pending CN101022789A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ53398204 2004-07-07
NZ533982 2004-07-07

Publications (1)

Publication Number Publication Date
CN101022789A true CN101022789A (zh) 2007-08-22

Family

ID=35783254

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800222148A Pending CN101022789A (zh) 2004-07-07 2005-07-07 一种药物组合物

Country Status (21)

Country Link
US (4) US20080275125A1 (enExample)
EP (1) EP1781277B1 (enExample)
JP (1) JP5630943B2 (enExample)
KR (1) KR101370712B1 (enExample)
CN (1) CN101022789A (enExample)
AT (1) ATE543491T1 (enExample)
AU (2) AU2005260243B2 (enExample)
BR (1) BRPI0512756A (enExample)
CA (1) CA2570474C (enExample)
CY (2) CY1112738T1 (enExample)
DK (1) DK1781277T3 (enExample)
ES (1) ES2381794T3 (enExample)
GB (1) GB2431346C (enExample)
LT (1) LTC1781277I2 (enExample)
MX (1) MX2007000117A (enExample)
PL (1) PL1781277T3 (enExample)
PT (1) PT1781277E (enExample)
RU (2) RU2007101686A (enExample)
SI (1) SI1781277T1 (enExample)
WO (1) WO2006004449A2 (enExample)
ZA (1) ZA200700896B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103298464A (zh) * 2010-11-04 2013-09-11 阿福特药物有限公司 复方组合物
CN113795243A (zh) * 2019-02-27 2021-12-14 Aft制药有限公司 含有对乙酰氨基酚和布洛芬的药物组合物
TWI922435B (zh) 2019-02-27 2026-04-21 紐西蘭商Ａｆｔ製藥有限公司 包含乙醯胺基酚及異布洛芬之醫藥組合物

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5630943B2 (ja) 2004-07-07 2014-11-26 エイ・エフ・ティ・ファーマスーティカルズ・リミテッドＡｆｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｉｍｉｔｅｄ 複合剤組成物
ZA200803566B (en) * 2005-12-12 2009-10-28 Adcock Ingram Ltd Pharmaceutical compositions
CN101563074B (zh) 2006-10-20 2012-11-07 麦克内尔-Ppc股份有限公司 乙酰氨基酚/布洛芬组合
JP5676834B2 (ja) * 2006-11-29 2015-02-25 エスエス製薬株式会社 消化管への刺激性を減少した経口固形組成物
WO2009012590A1 (en) * 2007-07-23 2009-01-29 Kingsway Pharmaceuticals Inc. Therapeutic formulations for the treatment of cold and flu-like symptoms
WO2009083759A1 (en) * 2008-01-03 2009-07-09 Wockhardt Research Centre Oral pharmaceutical suspension comprising paracetamol and ibuprofen
KR20110112279A (ko) * 2008-10-14 2011-10-12 에이에프티 파마슈티칼스 리미티드 의약품 및 치료
DE102010008876B4 (de) 2010-02-22 2017-07-27 Integrated Micro-Electronics Bulgaria Lichtquelle mit Array-LEDs zum direkten Betrieb am Wechselspannungsnetz und Herstellungsverfahren hierfür
MY164112A (en) * 2010-07-07 2017-11-30 Aft Pharmaceuticals Ltd A combination composition comprising ibuprofen and paracetamol
AU2012253834B2 (en) * 2011-05-06 2016-06-16 Glaxosmithkline Consumer Healthcare (Uk) Ip Limited Sustained release paracetamol formulations
JP6009928B2 (ja) * 2012-12-14 2016-10-19 ダイハツ工業株式会社 車両のサスペンション
KR102373089B1 (ko) * 2017-03-30 2022-03-11 한미약품 주식회사 이부프로펜 및 아세트아미노펜을 포함하는 약제학적 조성물 및 이의 제조방법
AU2018300075B2 (en) 2017-07-10 2024-02-29 Gel Cap Technologies, LLC Dual release dosage form capsule and methods, devices and systems for making same
EP3700509B1 (en) 2017-11-29 2023-11-22 Ilko Ilaç Sanayi Ve Ticaret Anonim Sirketi Color stable fixed dose tablet combination of ibuprofen and paracetamol
KR20220027194A (ko) 2019-06-27 2022-03-07 글락소스미스클라인 컨슈머 헬스케어 홀딩스 (유에스) 엘엘씨 신규 이부프로펜 및 아세트아미노펜 조성물
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU605538B2 (en) * 1988-01-19 1991-01-17 Adcock Ingram Limited Pharmaceutical unit
CA1336687C (en) * 1989-08-23 1995-08-15 Thomas M. Tencza Process for preparing tablets containing ibuprofen, apap and caffeine, the products of this process and the use of such products
JP3122748B2 (ja) * 1991-11-29 2001-01-09 ライオン株式会社 イブプロフェン含有解熱鎮痛剤
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations
ZA959469B (en) 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
KR970000231A (ko) * 1995-06-12 1997-01-21 박형미 진통소염제의 의약조성물
JP3982889B2 (ja) 1997-11-28 2007-09-26 あすか製薬株式会社 イブプロフェン含有医薬製剤
US6440983B1 (en) * 2000-12-21 2002-08-27 Mary Theresa Frank-Kollman Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers
JP5630943B2 (ja) 2004-07-07 2014-11-26 エイ・エフ・ティ・ファーマスーティカルズ・リミテッドＡｆｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｉｍｉｔｅｄ 複合剤組成物
GB0519350D0 (en) 2005-09-22 2005-11-02 Boots Healthcare Int Ltd Therapeutic agents
US20090264530A1 (en) 2008-04-16 2009-10-22 Nickell Robert P Combined nsaid and acetaminophen formulation and method
KR20110112279A (ko) 2008-10-14 2011-10-12 에이에프티 파마슈티칼스 리미티드 의약품 및 치료

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103298464A (zh) * 2010-11-04 2013-09-11 阿福特药物有限公司 复方组合物
CN107519159A (zh) * 2010-11-04 2017-12-29 阿福特药物有限公司 复方组合物
CN113795243A (zh) * 2019-02-27 2021-12-14 Aft制药有限公司 含有对乙酰氨基酚和布洛芬的药物组合物
TWI922435B (zh) 2019-02-27 2026-04-21 紐西蘭商Ａｆｔ製藥有限公司 包含乙醯胺基酚及異布洛芬之醫藥組合物

Also Published As

Publication number Publication date
AU2008202029A1 (en) 2009-11-26
CY2023026I1 (el) 2024-02-16
LTC1781277I2 (enExample) 2024-07-10
WO2006004449A2 (en) 2006-01-12
MX2007000117A (es) 2007-06-15
US20080200549A1 (en) 2008-08-21
ZA200700896B (en) 2008-07-30
GB2431346B (en) 2010-01-27
GB2431346C (en) 2010-02-17
ES2381794T3 (es) 2012-05-31
EP1781277A2 (en) 2007-05-09
CY2023026I2 (el) 2025-03-28
RU2010147287A (ru) 2012-05-27
DK1781277T3 (da) 2012-05-07
EP1781277A4 (en) 2008-09-03
JP5630943B2 (ja) 2014-11-26
RU2455983C1 (ru) 2012-07-20
CA2570474C (en) 2010-01-05
AU2005260243B2 (en) 2009-10-29
KR101370712B1 (ko) 2014-03-06
LTPA2024501I1 (enExample) 2024-02-12
AU2005260243A1 (en) 2006-01-12
CA2570474A1 (en) 2006-01-12
EP1781277B1 (en) 2012-02-01
WO2006004449A3 (en) 2006-03-02
US20080275125A1 (en) 2008-11-06
RU2007101686A (ru) 2008-08-20
JP2008505889A (ja) 2008-02-28
PT1781277E (pt) 2012-05-07
KR20070034614A (ko) 2007-03-28
GB0700027D0 (en) 2007-02-07
ATE543491T1 (de) 2012-02-15
GB2431346A (en) 2007-04-25
SI1781277T1 (sl) 2012-07-31
US20140073696A1 (en) 2014-03-13
US10532036B2 (en) 2020-01-14
BRPI0512756A (pt) 2008-04-08
CY1112738T1 (el) 2016-02-10
US20110275718A1 (en) 2011-11-10
PL1781277T3 (pl) 2012-07-31

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Application publication date: 20070822