GB2431346C - A combination composition comprising paracetamol and ibuprofen - Google Patents

A combination composition comprising paracetamol and ibuprofen Download PDF

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Publication number
GB2431346C
GB2431346C GB0700027A GB0700027A GB2431346C GB 2431346 C GB2431346 C GB 2431346C GB 0700027 A GB0700027 A GB 0700027A GB 0700027 A GB0700027 A GB 0700027A GB 2431346 C GB2431346 C GB 2431346C
Authority
GB
United Kingdom
Prior art keywords
paracetamol
ibuprofen
combination composition
combination
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB0700027A
Other languages
English (en)
Other versions
GB2431346B (en
GB0700027D0 (en
GB2431346A (en
Inventor
Hartley Campbell Atkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AFT Pharmaceuticals Ltd
Original Assignee
AFT Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AFT Pharmaceuticals Ltd filed Critical AFT Pharmaceuticals Ltd
Publication of GB0700027D0 publication Critical patent/GB0700027D0/en
Publication of GB2431346A publication Critical patent/GB2431346A/en
Publication of GB2431346B publication Critical patent/GB2431346B/en
Application granted granted Critical
Publication of GB2431346C publication Critical patent/GB2431346C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
GB0700027A 2004-07-07 2005-07-07 A combination composition comprising paracetamol and ibuprofen Expired - Lifetime GB2431346C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ53398204 2004-07-07
PCT/NZ2005/000168 WO2006004449A2 (en) 2004-07-07 2005-07-07 A combination composition

Publications (4)

Publication Number Publication Date
GB0700027D0 GB0700027D0 (en) 2007-02-07
GB2431346A GB2431346A (en) 2007-04-25
GB2431346B GB2431346B (en) 2010-01-27
GB2431346C true GB2431346C (en) 2010-02-17

Family

ID=35783254

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0700027A Expired - Lifetime GB2431346C (en) 2004-07-07 2005-07-07 A combination composition comprising paracetamol and ibuprofen

Country Status (21)

Country Link
US (4) US20080275125A1 (enExample)
EP (1) EP1781277B1 (enExample)
JP (1) JP5630943B2 (enExample)
KR (1) KR101370712B1 (enExample)
CN (1) CN101022789A (enExample)
AT (1) ATE543491T1 (enExample)
AU (2) AU2005260243B2 (enExample)
BR (1) BRPI0512756A (enExample)
CA (1) CA2570474C (enExample)
CY (2) CY1112738T1 (enExample)
DK (1) DK1781277T3 (enExample)
ES (1) ES2381794T3 (enExample)
GB (1) GB2431346C (enExample)
LT (1) LTC1781277I2 (enExample)
MX (1) MX2007000117A (enExample)
PL (1) PL1781277T3 (enExample)
PT (1) PT1781277E (enExample)
RU (2) RU2007101686A (enExample)
SI (1) SI1781277T1 (enExample)
WO (1) WO2006004449A2 (enExample)
ZA (1) ZA200700896B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5630943B2 (ja) 2004-07-07 2014-11-26 エイ・エフ・ティ・ファーマスーティカルズ・リミテッドAft Pharmaceuticals Limited 複合剤組成物
ZA200803566B (en) * 2005-12-12 2009-10-28 Adcock Ingram Ltd Pharmaceutical compositions
CN101563074B (zh) 2006-10-20 2012-11-07 麦克内尔-Ppc股份有限公司 乙酰氨基酚/布洛芬组合
JP5676834B2 (ja) * 2006-11-29 2015-02-25 エスエス製薬株式会社 消化管への刺激性を減少した経口固形組成物
WO2009012590A1 (en) * 2007-07-23 2009-01-29 Kingsway Pharmaceuticals Inc. Therapeutic formulations for the treatment of cold and flu-like symptoms
WO2009083759A1 (en) * 2008-01-03 2009-07-09 Wockhardt Research Centre Oral pharmaceutical suspension comprising paracetamol and ibuprofen
KR20110112279A (ko) * 2008-10-14 2011-10-12 에이에프티 파마슈티칼스 리미티드 의약품 및 치료
DE102010008876B4 (de) 2010-02-22 2017-07-27 Integrated Micro-Electronics Bulgaria Lichtquelle mit Array-LEDs zum direkten Betrieb am Wechselspannungsnetz und Herstellungsverfahren hierfür
MY164112A (en) * 2010-07-07 2017-11-30 Aft Pharmaceuticals Ltd A combination composition comprising ibuprofen and paracetamol
LT2635269T (lt) * 2010-11-04 2019-09-10 Aft Pharmaceuticals Limited Derinio kompozicija
AU2012253834B2 (en) * 2011-05-06 2016-06-16 Glaxosmithkline Consumer Healthcare (Uk) Ip Limited Sustained release paracetamol formulations
JP6009928B2 (ja) * 2012-12-14 2016-10-19 ダイハツ工業株式会社 車両のサスペンション
KR102373089B1 (ko) * 2017-03-30 2022-03-11 한미약품 주식회사 이부프로펜 및 아세트아미노펜을 포함하는 약제학적 조성물 및 이의 제조방법
AU2018300075B2 (en) 2017-07-10 2024-02-29 Gel Cap Technologies, LLC Dual release dosage form capsule and methods, devices and systems for making same
EP3700509B1 (en) 2017-11-29 2023-11-22 Ilko Ilaç Sanayi Ve Ticaret Anonim Sirketi Color stable fixed dose tablet combination of ibuprofen and paracetamol
US11197830B2 (en) * 2019-02-27 2021-12-14 Aft Pharmaceuticals Limited Pharmaceutical composition containing acetaminophen and ibuprofen
KR20220027194A (ko) 2019-06-27 2022-03-07 글락소스미스클라인 컨슈머 헬스케어 홀딩스 (유에스) 엘엘씨 신규 이부프로펜 및 아세트아미노펜 조성물
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU605538B2 (en) * 1988-01-19 1991-01-17 Adcock Ingram Limited Pharmaceutical unit
CA1336687C (en) * 1989-08-23 1995-08-15 Thomas M. Tencza Process for preparing tablets containing ibuprofen, apap and caffeine, the products of this process and the use of such products
JP3122748B2 (ja) * 1991-11-29 2001-01-09 ライオン株式会社 イブプロフェン含有解熱鎮痛剤
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations
ZA959469B (en) 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
KR970000231A (ko) * 1995-06-12 1997-01-21 박형미 진통소염제의 의약조성물
JP3982889B2 (ja) 1997-11-28 2007-09-26 あすか製薬株式会社 イブプロフェン含有医薬製剤
US6440983B1 (en) * 2000-12-21 2002-08-27 Mary Theresa Frank-Kollman Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers
JP5630943B2 (ja) 2004-07-07 2014-11-26 エイ・エフ・ティ・ファーマスーティカルズ・リミテッドAft Pharmaceuticals Limited 複合剤組成物
GB0519350D0 (en) 2005-09-22 2005-11-02 Boots Healthcare Int Ltd Therapeutic agents
US20090264530A1 (en) 2008-04-16 2009-10-22 Nickell Robert P Combined nsaid and acetaminophen formulation and method
KR20110112279A (ko) 2008-10-14 2011-10-12 에이에프티 파마슈티칼스 리미티드 의약품 및 치료

Also Published As

Publication number Publication date
AU2008202029A1 (en) 2009-11-26
CY2023026I1 (el) 2024-02-16
LTC1781277I2 (enExample) 2024-07-10
WO2006004449A2 (en) 2006-01-12
MX2007000117A (es) 2007-06-15
US20080200549A1 (en) 2008-08-21
ZA200700896B (en) 2008-07-30
GB2431346B (en) 2010-01-27
ES2381794T3 (es) 2012-05-31
EP1781277A2 (en) 2007-05-09
CY2023026I2 (el) 2025-03-28
RU2010147287A (ru) 2012-05-27
DK1781277T3 (da) 2012-05-07
EP1781277A4 (en) 2008-09-03
JP5630943B2 (ja) 2014-11-26
RU2455983C1 (ru) 2012-07-20
CA2570474C (en) 2010-01-05
AU2005260243B2 (en) 2009-10-29
KR101370712B1 (ko) 2014-03-06
LTPA2024501I1 (enExample) 2024-02-12
AU2005260243A1 (en) 2006-01-12
CA2570474A1 (en) 2006-01-12
EP1781277B1 (en) 2012-02-01
WO2006004449A3 (en) 2006-03-02
US20080275125A1 (en) 2008-11-06
RU2007101686A (ru) 2008-08-20
JP2008505889A (ja) 2008-02-28
PT1781277E (pt) 2012-05-07
CN101022789A (zh) 2007-08-22
KR20070034614A (ko) 2007-03-28
GB0700027D0 (en) 2007-02-07
ATE543491T1 (de) 2012-02-15
GB2431346A (en) 2007-04-25
SI1781277T1 (sl) 2012-07-31
US20140073696A1 (en) 2014-03-13
US10532036B2 (en) 2020-01-14
BRPI0512756A (pt) 2008-04-08
CY1112738T1 (el) 2016-02-10
US20110275718A1 (en) 2011-11-10
PL1781277T3 (pl) 2012-07-31

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Legal Events

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R108 Alteration of time limits (patents rules 1995)

Free format text: EXTENSION ALLOWED

Effective date: 20091218

Free format text: EXTENSION APPLICATION

Effective date: 20091215

PE20 Patent expired after termination of 20 years

Expiry date: 20250706