WO2006004449A3 - A combination composition - Google Patents

A combination composition Download PDF

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Publication number
WO2006004449A3
WO2006004449A3 PCT/NZ2005/000168 NZ2005000168W WO2006004449A3 WO 2006004449 A3 WO2006004449 A3 WO 2006004449A3 NZ 2005000168 W NZ2005000168 W NZ 2005000168W WO 2006004449 A3 WO2006004449 A3 WO 2006004449A3
Authority
WO
WIPO (PCT)
Prior art keywords
combination composition
combination
paracetamol
ibuprofen
treatment
Prior art date
Application number
PCT/NZ2005/000168
Other languages
French (fr)
Other versions
WO2006004449A2 (en
Inventor
Hartley Campbell Atkinson
Original Assignee
Aft Pharmaceuticals Ltd
Hartley Campbell Atkinson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to SI200531517T priority Critical patent/SI1781277T1/en
Priority to AT05764510T priority patent/ATE543491T1/en
Priority to PL05764510T priority patent/PL1781277T3/en
Priority to MX2007000117A priority patent/MX2007000117A/en
Priority to EP05764510A priority patent/EP1781277B1/en
Priority to CA002570474A priority patent/CA2570474C/en
Priority to GB0700027A priority patent/GB2431346C/en
Application filed by Aft Pharmaceuticals Ltd, Hartley Campbell Atkinson filed Critical Aft Pharmaceuticals Ltd
Priority to KR1020077002407A priority patent/KR101370712B1/en
Priority to US11/570,887 priority patent/US20080275125A1/en
Priority to ES05764510T priority patent/ES2381794T3/en
Priority to JP2007520251A priority patent/JP5630943B2/en
Priority to BRPI0512756-4A priority patent/BRPI0512756A/en
Priority to DK05764510.3T priority patent/DK1781277T3/en
Priority to AU2005260243A priority patent/AU2005260243B2/en
Publication of WO2006004449A2 publication Critical patent/WO2006004449A2/en
Publication of WO2006004449A3 publication Critical patent/WO2006004449A3/en
Priority to US12/113,171 priority patent/US20080200549A1/en
Priority to US12/924,812 priority patent/US20110275718A1/en
Priority to US13/857,802 priority patent/US10532036B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

A combination pharmaceutical composition for the treatment of pain including about 125 mg to about 150 mg ibuprofen and about 475 mg to about 500 mg paracetamol.
PCT/NZ2005/000168 2004-07-07 2005-07-07 A combination composition WO2006004449A2 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
DK05764510.3T DK1781277T3 (en) 2004-07-07 2005-07-07 Combination composition comprising Ibuprofen and Paracetamol
PL05764510T PL1781277T3 (en) 2004-07-07 2005-07-07 A combination composition comprising ibuprofen and paracetamol
MX2007000117A MX2007000117A (en) 2004-07-07 2005-07-07 A combination composition.
EP05764510A EP1781277B1 (en) 2004-07-07 2005-07-07 A combination composition comprising ibuprofen and paracetamol
CA002570474A CA2570474C (en) 2004-07-07 2005-07-07 A combination composition comprising paracetamol and ibuprofen
GB0700027A GB2431346C (en) 2004-07-07 2005-07-07 A combination composition comprising paracetamol and ibuprofen
ES05764510T ES2381794T3 (en) 2004-07-07 2005-07-07 A combination composition comprising ibuprofen and paracetamol
KR1020077002407A KR101370712B1 (en) 2004-07-07 2005-07-07 A combination composition
US11/570,887 US20080275125A1 (en) 2004-07-07 2005-07-07 Combination Composition
SI200531517T SI1781277T1 (en) 2004-07-07 2005-07-07 A combination composition comprising ibuprofen and paracetamol
JP2007520251A JP5630943B2 (en) 2004-07-07 2005-07-07 Composite agent composition
BRPI0512756-4A BRPI0512756A (en) 2004-07-07 2005-07-07 combination pharmaceutical composition for pain treatment, pain control method, use of a pharmaceutical composition and packaging including tablets or capsules
AT05764510T ATE543491T1 (en) 2004-07-07 2005-07-07 COMBINATION PREPARATION CONTAINING IBUPROFEN AND PARACETAMOL
AU2005260243A AU2005260243B2 (en) 2004-07-07 2005-07-07 A combination composition
US12/113,171 US20080200549A1 (en) 2004-07-07 2008-04-30 Pharmaceutical composition of ibuprofen and paracetamol and methods of using the same
US12/924,812 US20110275718A1 (en) 2004-07-07 2010-09-30 Pharmaceutical composition of ibuprofen and paracetamol and methods of using the same
US13/857,802 US10532036B2 (en) 2004-07-07 2013-04-05 Combination composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ533982 2004-07-07
NZ53398204 2004-07-07

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US11/570,887 A-371-Of-International US20080275125A1 (en) 2004-07-07 2005-07-07 Combination Composition
US12/113,171 Continuation-In-Part US20080200549A1 (en) 2004-07-07 2008-04-30 Pharmaceutical composition of ibuprofen and paracetamol and methods of using the same
US13/857,802 Continuation US10532036B2 (en) 2004-07-07 2013-04-05 Combination composition

Publications (2)

Publication Number Publication Date
WO2006004449A2 WO2006004449A2 (en) 2006-01-12
WO2006004449A3 true WO2006004449A3 (en) 2006-03-02

Family

ID=35783254

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NZ2005/000168 WO2006004449A2 (en) 2004-07-07 2005-07-07 A combination composition

Country Status (20)

Country Link
US (4) US20080275125A1 (en)
EP (1) EP1781277B1 (en)
JP (1) JP5630943B2 (en)
KR (1) KR101370712B1 (en)
CN (1) CN101022789A (en)
AT (1) ATE543491T1 (en)
AU (2) AU2005260243B2 (en)
BR (1) BRPI0512756A (en)
CA (1) CA2570474C (en)
CY (1) CY1112738T1 (en)
DK (1) DK1781277T3 (en)
ES (1) ES2381794T3 (en)
GB (1) GB2431346C (en)
MX (1) MX2007000117A (en)
PL (1) PL1781277T3 (en)
PT (1) PT1781277E (en)
RU (2) RU2007101686A (en)
SI (1) SI1781277T1 (en)
WO (1) WO2006004449A2 (en)
ZA (1) ZA200700896B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1781277T3 (en) 2004-07-07 2012-05-07 Aft Pharmaceuticals Ltd Combination composition comprising Ibuprofen and Paracetamol
WO2007069033A2 (en) * 2005-12-12 2007-06-21 Adcock Ingram Limited Pharmaceutical compositions comprising dexibuprofen, an opiate analgesic and paracetamol
AU2007309281B2 (en) * 2006-10-20 2013-10-31 Johnson & Johnson Consumer Inc. Acetaminophen / ibuprofen combinations
JP5676834B2 (en) * 2006-11-29 2015-02-25 エスエス製薬株式会社 Oral solid composition with reduced irritation to the gastrointestinal tract
AU2008280801B2 (en) * 2007-07-23 2014-03-06 Kingsway Pharmaceuticals Inc. Therapeutic formulations for the treatment of cold and flu-like symptoms
KR20110065417A (en) * 2008-01-03 2011-06-15 욱크하르트 리미티드 Oral pharmaceutical suspension comprising paracetamol and ibuprofen
AU2009304002B9 (en) * 2008-10-14 2014-06-26 Aft Pharmaceuticals Limited A medicinal product and treatment
DE102010008876B4 (en) 2010-02-22 2017-07-27 Integrated Micro-Electronics Bulgaria Light source with array LEDs for direct operation on the AC mains and manufacturing method thereof
AU2011274652B2 (en) * 2010-07-07 2013-08-15 Aft Pharmaceuticals Limited A combination composition comprising ibuprofen and paracetamol
WO2012060719A1 (en) * 2010-11-04 2012-05-10 Aft Pharmaceuticals Limited A combination composition
EA201391643A1 (en) * 2011-05-06 2014-07-30 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи COMPOSITIONS WITH DELAYED PARACETAMOL DELIVERY
JP6009928B2 (en) * 2012-12-14 2016-10-19 ダイハツ工業株式会社 Vehicle suspension
KR102373089B1 (en) * 2017-03-30 2022-03-11 한미약품 주식회사 Pharmaceutical composition comprising ibuprofen and acetaminophen and preparation method thereof
CN111031996B (en) * 2017-07-10 2022-04-15 盖尔凯普科技有限公司 Dual release dosage form capsule and method, apparatus and system for making same
WO2019108147A1 (en) 2017-11-29 2019-06-06 İlko İlaç Sanayi̇ Ve Ti̇caret A.Ş. Color stable fixed dose tablet combination of ibuprofen and paracetamol
US11197830B2 (en) 2019-02-27 2021-12-14 Aft Pharmaceuticals Limited Pharmaceutical composition containing acetaminophen and ibuprofen
AU2020301401B2 (en) * 2019-06-27 2023-12-21 Glaxosmithkline Consumer Healthcare Holdings (Us) Llc Novel ibuprofen and acetaminophen composition
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU605538B2 (en) * 1988-01-19 1991-01-17 Adcock Ingram Limited Pharmaceutical unit
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
CA1336687C (en) * 1989-08-23 1995-08-15 Thomas M. Tencza Process for preparing tablets containing ibuprofen, apap and caffeine, the products of this process and the use of such products

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3122748B2 (en) * 1991-11-29 2001-01-09 ライオン株式会社 Antipyretic analgesic containing ibuprofen
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations
ZA959469B (en) 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
KR970000231A (en) * 1995-06-12 1997-01-21 박형미 Pharmaceutical composition of analgesic anti-inflammatory
JP3982889B2 (en) 1997-11-28 2007-09-26 あすか製薬株式会社 Pharmaceutical preparations containing ibuprofen
US6440983B1 (en) * 2000-12-21 2002-08-27 Mary Theresa Frank-Kollman Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers
DK1781277T3 (en) 2004-07-07 2012-05-07 Aft Pharmaceuticals Ltd Combination composition comprising Ibuprofen and Paracetamol
GB0519350D0 (en) 2005-09-22 2005-11-02 Boots Healthcare Int Ltd Therapeutic agents
US20090264530A1 (en) 2008-04-16 2009-10-22 Nickell Robert P Combined nsaid and acetaminophen formulation and method
AU2009304002B9 (en) 2008-10-14 2014-06-26 Aft Pharmaceuticals Limited A medicinal product and treatment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU605538B2 (en) * 1988-01-19 1991-01-17 Adcock Ingram Limited Pharmaceutical unit
CA1336687C (en) * 1989-08-23 1995-08-15 Thomas M. Tencza Process for preparing tablets containing ibuprofen, apap and caffeine, the products of this process and the use of such products
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PICKERING A.E. ET AL: "Double-blind, placebo-controlled analgesic study of ibuprofen or rofecoxib in combination with paracetamol for tonsillectomy in children", BRITISH JOURNAL OF ANAESTHESIA, vol. 88, no. 1, 2002, pages 72 - 77, XP008097232 *

Also Published As

Publication number Publication date
EP1781277B1 (en) 2012-02-01
ES2381794T3 (en) 2012-05-31
DK1781277T3 (en) 2012-05-07
RU2007101686A (en) 2008-08-20
US20140073696A1 (en) 2014-03-13
MX2007000117A (en) 2007-06-15
EP1781277A2 (en) 2007-05-09
US10532036B2 (en) 2020-01-14
JP2008505889A (en) 2008-02-28
GB2431346C (en) 2010-02-17
CA2570474A1 (en) 2006-01-12
GB2431346A (en) 2007-04-25
PL1781277T3 (en) 2012-07-31
AU2008202029A1 (en) 2009-11-26
ZA200700896B (en) 2008-07-30
GB0700027D0 (en) 2007-02-07
CN101022789A (en) 2007-08-22
KR20070034614A (en) 2007-03-28
WO2006004449A2 (en) 2006-01-12
ATE543491T1 (en) 2012-02-15
JP5630943B2 (en) 2014-11-26
CY1112738T1 (en) 2016-02-10
SI1781277T1 (en) 2012-07-31
RU2010147287A (en) 2012-05-27
EP1781277A4 (en) 2008-09-03
RU2455983C1 (en) 2012-07-20
US20080200549A1 (en) 2008-08-21
BRPI0512756A (en) 2008-04-08
KR101370712B1 (en) 2014-03-06
US20080275125A1 (en) 2008-11-06
AU2005260243A1 (en) 2006-01-12
CA2570474C (en) 2010-01-05
AU2005260243B2 (en) 2009-10-29
US20110275718A1 (en) 2011-11-10
PT1781277E (en) 2012-05-07
GB2431346B (en) 2010-01-27

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