CN100537740C - 代谢活性微生物及其生产方法 - Google Patents

代谢活性微生物及其生产方法 Download PDF

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Publication number
CN100537740C
CN100537740C CNB2005800324851A CN200580032485A CN100537740C CN 100537740 C CN100537740 C CN 100537740C CN B2005800324851 A CNB2005800324851 A CN B2005800324851A CN 200580032485 A CN200580032485 A CN 200580032485A CN 100537740 C CN100537740 C CN 100537740C
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total amount
prepared product
growth
growth matrix
peptide
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Expired - Lifetime
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English (en)
Chinese (zh)
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CN101027387A (zh
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蒂莫西·图伯
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Multigerm UK Enterprises Ltd
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Multigerm UK Enterprises Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/169—Plantarum

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
CNB2005800324851A 2004-09-27 2005-09-27 代谢活性微生物及其生产方法 Expired - Lifetime CN100537740C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0421448A GB2418431A (en) 2004-09-27 2004-09-27 Metabolically active micro organisms and methods for their production
GB0421448.2 2004-09-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2009101495392A Division CN101603021B (zh) 2004-09-27 2005-09-27 代谢活性微生物及其生产方法

Publications (2)

Publication Number Publication Date
CN101027387A CN101027387A (zh) 2007-08-29
CN100537740C true CN100537740C (zh) 2009-09-09

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CNB2005800324851A Expired - Lifetime CN100537740C (zh) 2004-09-27 2005-09-27 代谢活性微生物及其生产方法
CN2009101495392A Expired - Lifetime CN101603021B (zh) 2004-09-27 2005-09-27 代谢活性微生物及其生产方法

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US (2) US8551473B2 (enExample)
EP (2) EP1794283B1 (enExample)
JP (1) JP5577020B2 (enExample)
CN (2) CN100537740C (enExample)
AU (1) AU2005288751B2 (enExample)
CA (1) CA2580949C (enExample)
EA (1) EA012968B1 (enExample)
ES (2) ES2568955T3 (enExample)
GB (1) GB2418431A (enExample)
NO (1) NO20072210L (enExample)
NZ (1) NZ553858A (enExample)
PL (2) PL3050960T3 (enExample)
WO (1) WO2006035218A1 (enExample)
ZA (1) ZA200702398B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101603021B (zh) * 2004-09-27 2013-04-24 马蒂吉姆英国企业有限公司 代谢活性微生物及其生产方法

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SE532899C2 (sv) 2007-06-08 2010-05-04 Probi Ab Förfarande genom fermentering med Lactobacillus plantarum för tillhandahållande av en insulinsvarsreducerande produkt och dess användning farmaceutiskt eller i livsmedel
BRPI0823218A2 (pt) * 2008-11-21 2014-10-14 Jose Antonio Cruz Serrano Método para obter uma mistura de probióticos, prebióticos nutrientes com ação simbiótica sinergística
GB201119774D0 (en) * 2011-11-16 2011-12-28 Multigerm Uk Entpr Ltd IBS treatment
ES2655668T3 (es) 2011-11-16 2018-02-21 Multigerm Uk Enterprises Ltd. Tratamiento del IBS con probióticos
GB201219873D0 (en) * 2012-11-05 2012-12-19 Multigerm Uk Entpr Ltd Diverticulitis treatment
DE102012110612A1 (de) * 2012-11-06 2014-05-08 Gelita Ag Kollagenhydrolysat und dessen Verwendung
CN105296541A (zh) * 2014-07-30 2016-02-03 无限极（中国）有限公司 燕麦发酵液及其制备方法与作为化妆品原料的应用
ES2575828B1 (es) * 2014-12-31 2017-07-07 Universidad De León Empleo de probióticos en el incremento de la fertilidad masculina
GB201501938D0 (en) 2015-02-05 2015-03-25 Multigerm Uk Entpr Ltd Probiotic preparation
WO2019118984A2 (en) 2017-12-15 2019-06-20 Solarea Bio, Inc. Microbial compositions and methods for treating type 2 diabetes, obesity, and metabolic syndrome
CN108315279A (zh) * 2018-04-09 2018-07-24 河南科技大学 一种植物乳杆菌液体制剂的长时间储存方法
KR20210021461A (ko) * 2018-06-19 2021-02-26 4디 파마 리서치 리미티드 살아있는 바이오치료 제품을 포함하는 제형
JPWO2020013239A1 (ja) * 2018-07-10 2021-05-13 学校法人慶應義塾 Ｄ−プシコース応答性増殖能を有する腸内細菌
EP3846830A4 (en) 2018-09-05 2022-07-06 Solarea Bio, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MUSCULOSKELETAL DISEASES
US11980647B2 (en) 2018-09-05 2024-05-14 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
CN109486713B (zh) * 2018-12-06 2021-03-09 福建傲农生物科技集团股份有限公司 一种液态复合乳酸杆菌制剂及其制备方法与应用
GB201915144D0 (en) * 2019-10-18 2019-12-04 Multigerm Uk Entpr Ltd Method of promoting SCFA production by gut microbiota
WO2021113850A2 (en) * 2019-12-06 2021-06-10 Nas Bioventures Llc Onsite installation or manufactured product of eco-friendly bacterial compositions, methods and systems for bioremediation in a short duration in different environments
CN116782771A (zh) * 2020-06-29 2023-09-19 加拿大生物芯公司 用于支持患有胃肠病症的伴侣动物的组合物和相关方法
EP4436407A1 (en) 2021-11-22 2024-10-02 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
US20230190834A1 (en) 2021-12-21 2023-06-22 Solarea Bio, Inc. Immunomodulatory compositions comprising microbial entities
GB202210523D0 (en) 2022-07-18 2022-08-31 Multigerm Uk Entpr Ltd Probiotic compositions and therapeutic uses thereof

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CN101603021B (zh) * 2004-09-27 2013-04-24 马蒂吉姆英国企业有限公司 代谢活性微生物及其生产方法

Also Published As

Publication number Publication date
JP5577020B2 (ja) 2014-08-20
PL1794283T3 (pl) 2016-10-31
AU2005288751A1 (en) 2006-04-06
CN101603021B (zh) 2013-04-24
EP1794283A1 (en) 2007-06-13
CN101603021A (zh) 2009-12-16
US20130011368A1 (en) 2013-01-10
EP1794283B1 (en) 2016-04-13
US8551473B2 (en) 2013-10-08
HK1134686A1 (en) 2010-05-07
CA2580949A1 (en) 2006-04-06
CA2580949C (en) 2017-07-25
GB2418431A (en) 2006-03-29
EA012968B1 (ru) 2010-02-26
PL3050960T3 (pl) 2018-05-30
ES2568955T3 (es) 2016-05-05
EP3050960B1 (en) 2017-12-13
ZA200702398B (en) 2008-10-29
EA200700613A1 (ru) 2007-10-26
WO2006035218A1 (en) 2006-04-06
CN101027387A (zh) 2007-08-29
JP2008514582A (ja) 2008-05-08
US20110158949A1 (en) 2011-06-30
NO20072210L (no) 2007-04-27
ES2654246T3 (es) 2018-02-12
AU2005288751B2 (en) 2010-12-23
EP3050960A1 (en) 2016-08-03
NZ553858A (en) 2009-01-31
GB0421448D0 (en) 2004-10-27

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Granted publication date: 20090909