CN100475757C - 用于饮食补充或用于制备治疗非胰岛素依赖性糖尿病、高血压和/或代谢综合征的药物的物质 - Google Patents
用于饮食补充或用于制备治疗非胰岛素依赖性糖尿病、高血压和/或代谢综合征的药物的物质 Download PDFInfo
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- CN100475757C CN100475757C CNB018058701A CN01805870A CN100475757C CN 100475757 C CN100475757 C CN 100475757C CN B018058701 A CNB018058701 A CN B018058701A CN 01805870 A CN01805870 A CN 01805870A CN 100475757 C CN100475757 C CN 100475757C
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- insulin
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- hypertension
- metabolic syndrome
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- 0 *[C@@]12C=*CC*1C2 Chemical compound *[C@@]12C=*CC*1C2 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C13/00—Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
- C07C13/28—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
- C07C13/32—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings
- C07C13/62—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with more than three condensed rings
- C07C13/66—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with more than three condensed rings the condensed ring system contains only four rings
- C07C13/68—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with more than three condensed rings the condensed ring system contains only four rings with a bridged ring system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/35—Unsaturated compounds having unsaturation outside the rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/86—Ring systems containing bridged rings containing four rings
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200000163 | 2000-02-01 | ||
| DKPA200000163 | 2000-02-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1416411A CN1416411A (zh) | 2003-05-07 |
| CN100475757C true CN100475757C (zh) | 2009-04-08 |
Family
ID=8159060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB018058701A Expired - Fee Related CN100475757C (zh) | 2000-02-01 | 2001-02-01 | 用于饮食补充或用于制备治疗非胰岛素依赖性糖尿病、高血压和/或代谢综合征的药物的物质 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US20030060428A1 (https=) |
| EP (2) | EP1255718A1 (https=) |
| JP (2) | JP2003521528A (https=) |
| CN (1) | CN100475757C (https=) |
| AU (1) | AU784422B2 (https=) |
| BR (1) | BR0108043A (https=) |
| CA (2) | CA2398445C (https=) |
| WO (1) | WO2001056959A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003521528A (ja) | 2000-02-01 | 2003-07-15 | ステヴィア,エイプス | 食事補強剤、又は非インシュリン依存性糖尿病、高血圧及び/又は代謝症候群の治療のための薬剤の調製に使用する物質 |
| BRPI0412189A (pt) * | 2003-06-30 | 2006-08-22 | Nestec Sa | composição para tratar e/ou prevenir disfunções associadas à diabetes melito do tipo 2 |
| AT502270B1 (de) * | 2005-02-21 | 2007-07-15 | Emakos Naturnahe Nahrungsmitte | Verfahren zum modifizieren von steviosid durch austauschreaktionen |
| US8956677B2 (en) * | 2005-11-23 | 2015-02-17 | The Coca-Cola Company | High-potency sweetener composition with glucosamine and compositions sweetened therewith |
| KR20080071606A (ko) * | 2005-11-23 | 2008-08-04 | 더 코카콜라 컴파니 | 시간 특성 및/또는 향미 특성이 개선된 인공 감미료조성물과 이들의 제제 방법 및 용도 |
| US9144251B2 (en) * | 2005-11-23 | 2015-09-29 | The Coca-Cola Company | High-potency sweetener composition with mineral and compositions sweetened therewith |
| AU2006318781B2 (en) * | 2005-11-23 | 2012-11-01 | The Coca-Cola Company | Natural high-potency sweetener compositions with improved temporal profile and/or flavor profile, methods for their formulation, and uses |
| US8940350B2 (en) * | 2005-11-23 | 2015-01-27 | The Coca-Cola Company | Cereal compositions comprising high-potency sweeteners |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| US20070116831A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | Dental Composition with High-Potency Sweetener |
| US8524304B2 (en) * | 2005-11-23 | 2013-09-03 | The Coca-Cola Company | High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith |
| US8956678B2 (en) * | 2005-11-23 | 2015-02-17 | The Coca-Cola Company | High-potency sweetener composition with preservative and compositions sweetened therewith |
| US8993027B2 (en) * | 2005-11-23 | 2015-03-31 | The Coca-Cola Company | Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses |
| US8524303B2 (en) * | 2005-11-23 | 2013-09-03 | The Coca-Cola Company | High-potency sweetener composition with phytosterol and compositions sweetened therewith |
| US20070134391A1 (en) * | 2005-11-23 | 2007-06-14 | The Coca-Cola Company | High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith |
| US8940351B2 (en) * | 2005-11-23 | 2015-01-27 | The Coca-Cola Company | Baked goods comprising high-potency sweetener |
| US8435588B2 (en) * | 2005-11-23 | 2013-05-07 | The Coca-Cola Company | High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith |
| US20070116836A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith |
| US8367138B2 (en) * | 2005-11-23 | 2013-02-05 | The Coca-Cola Company | Dairy composition with high-potency sweetener |
| US20070116822A1 (en) * | 2005-11-23 | 2007-05-24 | The Coca-Cola Company | High-potency sweetener composition with saponin and compositions sweetened therewith |
| EP2380566A3 (en) * | 2006-09-15 | 2012-04-11 | Stevia APS | Treatment of insulin resistance or diseases associated with insulin resistance using steviol or isosteviol |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| US9101161B2 (en) * | 2006-11-02 | 2015-08-11 | The Coca-Cola Company | High-potency sweetener composition with phytoestrogen and compositions sweetened therewith |
| US20080107787A1 (en) * | 2006-11-02 | 2008-05-08 | The Coca-Cola Company | Anti-Diabetic Composition with High-Potency Sweetener |
| EP2155769B1 (en) | 2007-05-04 | 2012-06-27 | Katholieke Universiteit Leuven KU Leuven Research & Development | Tissue degeneration protection |
| MY155722A (en) * | 2007-12-03 | 2015-11-30 | Dsm Ip Assets Bv | Novel nutraceutical compositions containing stevia extract or stevia extract constituents and uses thereof |
| WO2009071099A1 (en) * | 2007-12-05 | 2009-06-11 | Aarhus Universitet | Elevation of the plasma hdl-cholesterol level |
| US8759405B2 (en) * | 2009-07-21 | 2014-06-24 | Dsm Ip Assets B.V. | Stevia extract or steviol for hair care |
| WO2011033524A2 (en) | 2009-08-04 | 2011-03-24 | Laila Nutraceuticals | Agents from ficus hispida for the amelioration of metabolic syndrome and related diseases |
| US20110189360A1 (en) * | 2010-02-04 | 2011-08-04 | Pepsico, Inc. | Method to Increase Solubility Limit of Rebaudioside D in an Aqueous Solution |
| WO2012127287A2 (en) * | 2011-03-18 | 2012-09-27 | Febris Bio-Tech Limited | Compositions and methods for treating multi-drug resistant malaria |
| EP2988754A1 (en) | 2013-04-23 | 2016-03-02 | Aarhus Universitet | Compositions for use in restoring muscle glycogen and/or muscle mass |
| RU2525593C1 (ru) * | 2013-05-24 | 2014-08-20 | Государственное бюджетное образовательное учреждение дополнительного профессионального образования "Новокузнецкий государственный институт усовершенствования врачей" Министерства здравоохранения Российской Федерации | Способ комплексного лечения артериальной гипертонии при метаболических нарушениях |
| TWI516474B (zh) | 2013-05-27 | 2016-01-11 | 中央研究院 | 良薑化合物及其類似物之合成 |
| AU2014279129B2 (en) | 2013-06-10 | 2018-07-12 | Suntory Holdings Limited | Plant extract containing diketopiperazine and method for producing same |
| SG11201800675PA (en) * | 2015-07-27 | 2018-02-27 | Suntory Holdings Ltd | Composition containing cyclic dipeptide and sweetening agent |
| CA3015700A1 (en) * | 2015-09-10 | 2017-03-16 | Key-Pharma Biomedical Inc. | The use of kauranes compounds in the manufacture of medicament for treatment of cardiac hypertropy and pulmonary hypertension |
| MX2019004534A (es) | 2016-10-20 | 2019-10-02 | Coca Cola Co | Glicosidos de diterpénicos aislados a partir de stevia, composiciones y métodos. |
| CN108159034B (zh) * | 2018-02-12 | 2019-10-11 | 东南大学 | 异甜菊醇在制备治疗非酒精性脂肪性肝病药物中的应用 |
| WO2020218382A1 (ja) * | 2019-04-26 | 2020-10-29 | サントリーホールディングス株式会社 | Glp-1分泌促進剤 |
| CN111357979A (zh) * | 2019-12-26 | 2020-07-03 | 浙江欧谱生物科技有限公司 | 抑制高脂引起的肥胖及骨丢失的保健食品组合物及其应用 |
| CN111233702A (zh) * | 2020-01-20 | 2020-06-05 | 中国科学院昆明植物研究所 | 先花铃子香素a衍生物与其药物组合物及其制备方法和应用 |
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| CN1195486A (zh) * | 1997-04-04 | 1998-10-14 | 青岛海洋大学 | 双纤维降糖粉及其制造方法 |
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| JP2003521528A (ja) | 2000-02-01 | 2003-07-15 | ステヴィア,エイプス | 食事補強剤、又は非インシュリン依存性糖尿病、高血圧及び/又は代謝症候群の治療のための薬剤の調製に使用する物質 |
| EP1361870A2 (en) | 2001-02-01 | 2003-11-19 | Nutri Pharma ASA | A substance for use in a dietary supplement or for the preparation of a medicament for the treatment of non-insulin dependent diabetes mellitus, hypertension and/or the metabolic syndrome |
| US20090232913A1 (en) | 2005-05-02 | 2009-09-17 | Momir Mikov | Composition for the Control of Cholesterol Levels |
| WO2007047803A2 (en) * | 2005-10-20 | 2007-04-26 | Ghc Research Development Corporation | Use of prolactin in the prophylactic treatment of cancer |
| EP2380566A3 (en) * | 2006-09-15 | 2012-04-11 | Stevia APS | Treatment of insulin resistance or diseases associated with insulin resistance using steviol or isosteviol |
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2001
- 2001-02-01 JP JP2001556812A patent/JP2003521528A/ja not_active Withdrawn
- 2001-02-01 BR BR0108043-1A patent/BR0108043A/pt not_active IP Right Cessation
- 2001-02-01 CN CNB018058701A patent/CN100475757C/zh not_active Expired - Fee Related
- 2001-02-01 AU AU30028/01A patent/AU784422B2/en not_active Ceased
- 2001-02-01 WO PCT/DK2001/000075 patent/WO2001056959A1/en not_active Ceased
- 2001-02-01 EP EP01902290A patent/EP1255718A1/en not_active Ceased
- 2001-02-01 EP EP10157966A patent/EP2330092A3/en not_active Withdrawn
- 2001-02-01 CA CA2398445A patent/CA2398445C/en not_active Expired - Fee Related
- 2001-02-01 CA CA2762121A patent/CA2762121A1/en not_active Abandoned
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2002
- 2002-07-31 US US10/210,787 patent/US20030060428A1/en not_active Abandoned
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2004
- 2004-09-03 US US10/933,297 patent/US20050038126A1/en not_active Abandoned
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2007
- 2007-06-28 US US11/819,659 patent/US20080051341A1/en not_active Abandoned
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2008
- 2008-08-07 US US12/187,487 patent/US20080318866A1/en not_active Abandoned
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2012
- 2012-05-16 JP JP2012112329A patent/JP2012153721A/ja active Pending
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2013
- 2013-06-13 US US13/917,032 patent/US9636314B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1195486A (zh) * | 1997-04-04 | 1998-10-14 | 青岛海洋大学 | 双纤维降糖粉及其制造方法 |
Non-Patent Citations (4)
| Title |
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| 甜叶醇的结构改造及生物活性试验. 刘秀芳等.武汉大学学报(自然科学版),第2期. 1994 |
| 甜叶醇的结构改造及生物活性试验. 刘秀芳等.武汉大学学报(自然科学版),第2期. 1994 * |
| 甜菊甙提取的中间试验. 林启先等人.中国医药工业杂志,第22卷第9期. 1991 |
| 甜菊甙提取的中间试验. 林启先等人.中国医药工业杂志,第22卷第9期. 1991 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1416411A (zh) | 2003-05-07 |
| WO2001056959A1 (en) | 2001-08-09 |
| CA2398445A1 (en) | 2001-08-09 |
| EP1255718A1 (en) | 2002-11-13 |
| US20080318866A1 (en) | 2008-12-25 |
| JP2012153721A (ja) | 2012-08-16 |
| EP2330092A3 (en) | 2012-07-25 |
| AU3002801A (en) | 2001-08-14 |
| WO2001056959B1 (en) | 2002-02-07 |
| US9636314B2 (en) | 2017-05-02 |
| AU784422B2 (en) | 2006-03-30 |
| CA2398445C (en) | 2012-04-03 |
| JP2003521528A (ja) | 2003-07-15 |
| US20080051341A1 (en) | 2008-02-28 |
| US20030060428A1 (en) | 2003-03-27 |
| US20140094408A1 (en) | 2014-04-03 |
| CA2762121A1 (en) | 2001-08-09 |
| US20050038126A1 (en) | 2005-02-17 |
| EP2330092A2 (en) | 2011-06-08 |
| BR0108043A (pt) | 2003-04-01 |
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