CN100443896C - 一种治疗泌尿系疾病的药物的质量控制方法 - Google Patents
一种治疗泌尿系疾病的药物的质量控制方法 Download PDFInfo
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- 230000001575 pathological effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000010079 rubber tapping Methods 0.000 description 1
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 238000002562 urinalysis Methods 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
组别 | 剂量(/kg) | N | 结石重量(mg,X±S) |
受试药物 | 1.60g | 9 | 1.69±0.51* |
受试药物 | 0.80g | 10 | 2.01±1.30 |
受试药物 | 0.40g | 10 | 1.97±0.65 |
结石通 | 10g | 10 | 1.72±0.73 |
常水 | 10ml | 10 | 2.41±0.62 |
组别 | 浓度(生药g%) | 结石浸泡前重量(mg) | 溶石率(%) | 浸泡液钙含量(mmol/L) |
受试药物 | 78.6 | 83.6±44.7 | 2.4±3.2 | 1.081±0.404* |
受试药物 | 20.6 | 84.8±41.8 | 2.0±2.6 | 0.323±0.156 |
结石通 | 100 | 83.9±41.2 | 1.7±2.2 | 1.176±0.743 |
去离子水 | - | 82.8±38.9 | 5.6±8.3 | 0.612±0.418 |
组别 | n | 剂量(/kg) | 15分钟扭体次数(X±S) | 抑制率(%) |
受试药物 | 10 | 2.60g | 18.6±9.86 | 18.6 |
受试药物 | 10 | 1.30g | 19.7±9.08 | 17.5 |
受试药物 | 10 | 0.65g | 19.2±10.1 | 16.2 |
罗通定 | 10 | 80mg | 5.6±3.09** | 76.5 |
常水 | 10 | 20ml | 22.9±15.5 |
组别 | n | 剂量(/kg) | OD(X±S) | 抑制率(%) |
受试药物 | 10 | 2.60g | 0.081±0.030** | 49.8 |
受试药物 | 10 | 1.30g | 0.111±0.045* | 31.9 |
受试药物 | 10 | 0.65g | 0.131±0.056 | 23.4 |
泼尼松 | 10 | 20mg | 0.103±0.041* | 34.1 |
常水 | 10 | 20ml | 0.161±0.054 |
组别 | 剂量(/kg) | n | 7天内死亡数 |
受试药物 | 1.60g | 10 | 9 |
受试药物 | 0.80g | 10 | 10 |
受试药物 | 0.40g | 10 | 10 |
诺氟沙星 | 600mg | 10 | 1 |
常水 | 20ml | 10 | 9 |
组别 | 剂量(/kg) | n | 7天内死亡数 |
受试药物 | 1.60g | 10 | 6 |
受试药物 | 0.80g | 10 | 9 |
受试药物 | 0.40g | 10 | 10 |
TMP+SMZ | 768mg | 10 | 0** |
常水 | 20ml | 10 | 9 |
菌种 | 菌号 | MIC(原药材g/L) |
大肠杆菌 | CMCC(B)44102 | 60.2 |
副大肠杆菌 | 临床株 | 60.3 |
变形杆菌 | CMCC(B)49102 | 13.9 |
金黄色葡萄球菌 | CMCC(B)26003 | 60.2 |
绿脓杆菌 | CMCC(B)10104 | 60.0 |
Claims (1)
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CN105475767A (zh) * | 2015-12-19 | 2016-04-13 | 林曦之 | 一种防治癃闭饮料及其制备方法 |
CN105412667A (zh) * | 2015-12-19 | 2016-03-23 | 林曦之 | 治疗癃闭的药酒及其制备方法 |
CN106442275B (zh) * | 2016-09-18 | 2019-08-09 | 中国人民武装警察部队总医院 | 一种定性检测乳糜的方法及试剂盒 |
CN107976509B (zh) * | 2017-11-01 | 2020-04-07 | 广西壮族自治区食品药品检验所 | 沙牛的薄层色谱鉴别方法 |
CN110201053B (zh) * | 2019-07-15 | 2021-07-09 | 河南白马健康产业有限公司 | 一种苗药前列腺贴及其制备方法 |
CN111467415A (zh) * | 2020-05-22 | 2020-07-31 | 沈阳东新药业有限公司 | 一种五淋化石胶囊的治疗用途 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1091662A (zh) * | 1993-10-13 | 1994-09-07 | 梧州市人民制药厂 | 治疗尿石症和泌尿系感染的药物—五淋化石丹 |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1091662A (zh) * | 1993-10-13 | 1994-09-07 | 梧州市人民制药厂 | 治疗尿石症和泌尿系感染的药物—五淋化石丹 |
Non-Patent Citations (3)
Title |
---|
中华人民共和国卫生部药品标准 中药成方制剂 第14册. 195,药典委员会. 1997 中华人民共和国卫生部药品标准 中药成方制剂 第41册. 87,药典委员会. 2003 |
中华人民共和国卫生部药品标准 中药成方制剂 第14册. 195,药典委员会. 1997 * |
中华人民共和国卫生部药品标准 中药成方制剂 第41册. 87,药典委员会. 2003 * |
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