CN100379851C - 生成l-苏氨酸的微生物、生产其的方法、及使用其生产l-苏氨酸的方法 - Google Patents

生成l-苏氨酸的微生物、生产其的方法、及使用其生产l-苏氨酸的方法 Download PDF

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CN100379851C
CN100379851C CNB2005100079279A CN200510007927A CN100379851C CN 100379851 C CN100379851 C CN 100379851C CN B2005100079279 A CNB2005100079279 A CN B2005100079279A CN 200510007927 A CN200510007927 A CN 200510007927A CN 100379851 C CN100379851 C CN 100379851C
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threonine
microorganism
producing
gene
escherichia coli
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CN1654634A (zh
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朴英薰
李炳春
赵光命
金大哲
申容旭
李镇浩
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CJ CheilJedang Corp
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CJ Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)

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  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNB2005100079279A 2004-02-05 2005-02-05 生成l-苏氨酸的微生物、生产其的方法、及使用其生产l-苏氨酸的方法 Expired - Lifetime CN100379851C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020040007529 2004-02-05
KR1020040007529A KR100576342B1 (ko) 2004-02-05 2004-02-05 ｇａｌＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한Ｌ-쓰레오닌의 제조방법
KR10-2004-0007529 2004-02-05

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CN1654634A CN1654634A (zh) 2005-08-17
CN100379851C true CN100379851C (zh) 2008-04-09

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US (1) US7229794B2 (enExample)
EP (1) EP1561811B1 (enExample)
KR (1) KR100576342B1 (enExample)
CN (1) CN100379851C (enExample)
AT (1) ATE553210T1 (enExample)
BR (1) BRPI0507347A (enExample)
ES (1) ES2382473T3 (enExample)
PL (1) PL1561811T3 (enExample)
WO (1) WO2005075625A1 (enExample)

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KR100885616B1 (ko) * 2006-06-26 2009-02-24 씨제이제일제당 (주) 글리세롤을 이용한 아미노산의 생산 방법
KR100905381B1 (ko) 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
KR100837842B1 (ko) 2006-08-10 2008-06-13 씨제이제일제당 (주) 아스파테이트 세미알데히드 디하이드로게나아제 활성이증가된 ｌ-쓰레오닌 생산 미생물 및 이를 이용한ｌ-쓰레오닌 생산 방법
KR100924904B1 (ko) 2007-11-20 2009-11-02 씨제이제일제당 (주) 글리세롤을 포함한 탄소원을 이용할 수 있는코리네박테리아 및 이를 이용하여 발효산물을 생산하는방법
KR100966324B1 (ko) * 2008-01-08 2010-06-28 씨제이제일제당 (주) 향상된 ｌ－쓰레오닌 생산능을 갖는 대장균 및 이를 이용한ｌ－쓰레오닌의 생산 방법
US9005952B2 (en) 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
US7851180B2 (en) * 2008-04-04 2010-12-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
KR101058893B1 (ko) * 2009-03-03 2011-08-23 씨제이제일제당 (주) Ｌ-아미노산 생산 미생물 및 이를 이용한 ｌ-아미노산 생산방법
US8283152B2 (en) 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
JP2012223092A (ja) 2009-08-28 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2501797A4 (en) 2009-11-18 2013-04-17 Myriant Corp TECHNIQUES OF MICROBES FOR THE EFFECTIVE MANUFACTURE OF CHEMICALS
KR101261147B1 (ko) 2011-01-18 2013-05-06 씨제이제일제당 (주) Ｌ-아미노산의 생산능이 향상된 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
KR101327093B1 (ko) 2012-01-06 2013-11-07 씨제이제일제당 (주) Ｌ-아미노산을 생산할 수 있는 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
KR101646310B1 (ko) 2013-06-24 2016-08-12 씨제이제일제당 (주) L-쓰레오닌 생산 미생물 및 이를 이용한 l-쓰레오닌의 생산방법
KR101565213B1 (ko) 2013-10-23 2015-11-03 씨제이제일제당 (주) Ｏ-숙시닐호모세린 생산 미생물 및 이를 이용한 ｏ-숙시닐호모세린의 생산방법
KR101996767B1 (ko) 2018-11-29 2019-07-04 씨제이제일제당 (주) cAMP 수용 단백질 변이체 및 이를 이용한 L-아미노산 제조방법
KR101991206B1 (ko) 2018-11-29 2019-06-19 씨제이제일제당 (주) cAMP 수용 단백질 변이체 및 이를 이용한 L-아미노산 제조방법
KR101991207B1 (ko) 2018-11-29 2019-06-19 씨제이제일제당 (주) cAMP 수용 단백질 변이체 및 이를 이용한 L-아미노산 제조방법

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996034961A1 (en) * 1995-05-05 1996-11-07 Genencor International, Inc. Application of glucose transport mutants for production of aromatic pathway compounds
CN1373226A (zh) * 2001-02-13 2002-10-09 味之素株式会社 通过大肠杆菌属细菌生产l－氨基酸的方法
WO2003008603A2 (en) * 2001-07-18 2003-01-30 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteri acea family which contain an attenuated aspa gene
CN1430672A (zh) * 2000-05-27 2003-07-16 德古萨股份公司 发酵制备l－苏氨酸的方法
CN1446914A (zh) * 2002-03-21 2003-10-08 第一制糖株式会社 L－苏氨酸生产方法
CN1457365A (zh) * 2001-02-13 2003-11-19 第一制糖株式会社 L－苏氨酸的生产方法
CN1466630A (zh) * 2000-09-30 2004-01-07 德古萨股份公司 使用肠细菌科菌株发酵生产l-氨基酸的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
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KR920008365B1 (ko) 1990-12-31 1992-09-26 제일제당 주식회사 L-스레오닌 제조방법
DE10314618A1 (de) * 2003-04-01 2004-10-14 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996034961A1 (en) * 1995-05-05 1996-11-07 Genencor International, Inc. Application of glucose transport mutants for production of aromatic pathway compounds
CN1430672A (zh) * 2000-05-27 2003-07-16 德古萨股份公司 发酵制备l－苏氨酸的方法
CN1466630A (zh) * 2000-09-30 2004-01-07 德古萨股份公司 使用肠细菌科菌株发酵生产l-氨基酸的方法
CN1373226A (zh) * 2001-02-13 2002-10-09 味之素株式会社 通过大肠杆菌属细菌生产l－氨基酸的方法
CN1457365A (zh) * 2001-02-13 2003-11-19 第一制糖株式会社 L－苏氨酸的生产方法
WO2003008603A2 (en) * 2001-07-18 2003-01-30 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteri acea family which contain an attenuated aspa gene
CN1446914A (zh) * 2002-03-21 2003-10-08 第一制糖株式会社 L－苏氨酸生产方法

Non-Patent Citations (2)

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Title
Expression of galP and glk in a Escherichia coli PTSmutant restores glucose transport and increases glycolytic fluxto fermentation products.. Hernandez-Montalvo Veronica, et al.Biotechnology and Bioengineering.,Vol.83 No.6. 2003 *
Further inducibility of a constitutive system ultrainduction ofthe gal operon.. Tokeson JPE, et al.Journal of Bacteriology.,Vol.173 No.6. 1991 *

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Publication number Publication date
ES2382473T3 (es) 2012-06-08
BRPI0507347A (pt) 2007-07-03
US20050176114A1 (en) 2005-08-11
KR100576342B1 (ko) 2006-05-03
BRPI0507347B8 (enExample) 2021-05-25
PL1561811T3 (pl) 2012-08-31
US7229794B2 (en) 2007-06-12
KR20050079344A (ko) 2005-08-10
ATE553210T1 (de) 2012-04-15
WO2005075625A1 (en) 2005-08-18
BRPI0507347B1 (pt) 2005-08-18
CN1654634A (zh) 2005-08-17
EP1561811B1 (en) 2012-04-11
EP1561811A1 (en) 2005-08-10

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