CN100340233C - 包含三种聚合物的协同组合的眼用组合物 - Google Patents

包含三种聚合物的协同组合的眼用组合物 Download PDF

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Publication number
CN100340233C
CN100340233C CNB2004800159686A CN200480015968A CN100340233C CN 100340233 C CN100340233 C CN 100340233C CN B2004800159686 A CNB2004800159686 A CN B2004800159686A CN 200480015968 A CN200480015968 A CN 200480015968A CN 100340233 C CN100340233 C CN 100340233C
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China
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composition
right amount
polymer
viscosity
compositions
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Expired - Fee Related
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CNB2004800159686A
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English (en)
Chinese (zh)
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CN1802148A (zh
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M·A·乔罕
陈华刚
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Alcon Inc
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Alcon Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CNB2004800159686A 2003-06-13 2004-06-08 包含三种聚合物的协同组合的眼用组合物 Expired - Fee Related CN100340233C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47871303P 2003-06-13 2003-06-13
US60/478,713 2003-06-13

Publications (2)

Publication Number Publication Date
CN1802148A CN1802148A (zh) 2006-07-12
CN100340233C true CN100340233C (zh) 2007-10-03

Family

ID=33539115

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2004800159686A Expired - Fee Related CN100340233C (zh) 2003-06-13 2004-06-08 包含三种聚合物的协同组合的眼用组合物

Country Status (20)

Country Link
US (4) US7244440B2 (enExample)
EP (1) EP1633324B1 (enExample)
JP (2) JP4657213B2 (enExample)
KR (1) KR101082345B1 (enExample)
CN (1) CN100340233C (enExample)
AR (1) AR047205A1 (enExample)
AT (1) ATE348600T1 (enExample)
AU (1) AU2004249136B2 (enExample)
BR (1) BRPI0411367B1 (enExample)
CA (1) CA2527417C (enExample)
CY (1) CY1105877T1 (enExample)
DE (1) DE602004003812T2 (enExample)
DK (1) DK1633324T3 (enExample)
ES (1) ES2274476T3 (enExample)
MX (1) MXPA05013293A (enExample)
PL (1) PL1633324T3 (enExample)
PT (1) PT1633324E (enExample)
TW (1) TWI336257B (enExample)
WO (1) WO2004112750A2 (enExample)
ZA (1) ZA200509441B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI658828B (zh) * 2014-10-31 2019-05-11 中國醫藥大學 用於舒緩及減輕近視之醫藥組合物及其製備方法與用途

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TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
JP4860475B2 (ja) * 2003-06-13 2012-01-25 アルコン，インコーポレイテッド ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物
ES2593113T3 (es) 2003-08-07 2016-12-05 Allergan, Inc. Composiciones para el suministro de agentes terapéuticos en los ojos y métodos para obtener y usar los mismos
CA2567418C (en) * 2004-05-27 2012-12-04 Santen Pharmaceutical Co., Ltd. Viscous agent for ophthalmic use
EP1962803A1 (en) * 2005-12-23 2008-09-03 Alcon, Inc. PHARMACEUTICAL FORMULATION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE
FR2896152B1 (fr) * 2006-01-17 2016-01-08 Cetem Lab Nouvelles compositions cosmetiques et leur utilisation pour l'application sur les muqueuses
AR062046A1 (es) 2006-07-25 2008-08-10 Osmotica Pharmaceutical Argentina S A Soluciones oftalmicas
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
BRPI0806967A2 (pt) * 2007-02-09 2014-04-08 Alcon Inc Composições oftálmicas contendo uma combinação sinérgica de três polímeros
ES2557931T3 (es) 2007-08-08 2016-01-29 Lexicon Pharmaceuticals, Inc. (7H-Pirrolo[2,3-d]pirimidin-4-il)-piperazinas como inhibidores de cinasas para el tratamiento de cáncer e inflamación
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
WO2009110009A2 (en) * 2008-03-07 2009-09-11 Sun Pharma Advanced Research Company Ltd., Opthalmic composition
EP2674433A1 (en) 2008-04-21 2013-12-18 Lexicon Pharmaceuticals, Inc. LIMK2 inhibitors, compositions comprising them and methods of their use
AR071834A1 (es) 2008-04-26 2010-07-21 Alcon Res Ltd Sistema polimerico de lagrimas artificiales
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
TWI547522B (zh) * 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
SI2965749T1 (sl) 2009-12-03 2018-09-28 Novartis Ag Suspenzije nanodelcev, ki vsebujejo karboksivinilni polimer
EP2525794A1 (en) 2010-01-22 2012-11-28 Lexicon Pharmaceuticals, Inc. 5-(1h-pyrazol-5-yl)thiazole-based compounds for the treatment of diseases and disorders of the eye
DE102010009475B4 (de) 2010-02-26 2011-11-24 F. Holzer Gmbh Verfahren zur Herstellung eines dosierbaren applikationsfertigen Präparates
MX2012012826A (es) * 2010-05-05 2013-01-28 Alcon Res Ltd Formulaciones de galactomanana oftalmicas estabilizadas.
SG11201403013VA (en) * 2011-12-07 2014-07-30 Allergan Inc Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
FR2988297B1 (fr) * 2012-03-22 2014-03-28 Thea Lab Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
JP7526718B2 (ja) * 2019-02-27 2024-08-01 参天製薬株式会社 ジクアホソルまたはその塩、ビニル系高分子およびセルロース系高分子を含有する眼科用組成物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5460834A (en) * 1991-12-13 1995-10-24 Alcon Laboratories, Inc. Combinations of polymers for use in physiological tear compositions
US20020123482A1 (en) * 2000-12-21 2002-09-05 Chowhan Masood A. Artificial tear composition containing a combination of three demulcents

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US3355336A (en) 1966-08-18 1967-11-28 Du Pont Thickened water-bearing inorganic oxidizer salt explosive containing crosslinked galactomannan and polyacrylamide
NL188266C (nl) * 1975-07-29 1992-05-18 Merck & Co Inc Werkwijze ter bereiding van een oogheelkundig inplantaat.
US4039662A (en) * 1975-12-04 1977-08-02 Alcon Laboratories, Inc. Ophthalmic solution
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4767463A (en) 1987-04-15 1988-08-30 Union Carbide Corporation Glycosaminoglycan and cationic polymer combinations
US5368843A (en) 1988-06-08 1994-11-29 Lever Brothers Company, Division Of Conopco, Inc. Thickening system
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5252318A (en) 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
WO1993017664A1 (en) * 1992-03-02 1993-09-16 Alcon Laboratories, Inc. Combinations of cellulosic polymers and carboxy vinyl polymers and their use in pharmaceutical compositions
CA2134376C (en) * 1993-12-20 2001-10-23 Haresh G. Bhagat Combinations of polymers for use in physiological tear compositions
ATE166227T1 (de) * 1994-03-18 1998-06-15 Senju Pharma Co Sarpogrelat enthaltende opthalmologische zubereitungen zur senkung des intraokularen druckes
US5939485A (en) 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
ES2227331T3 (es) 1997-07-29 2005-04-01 Alcon Laboratories, Inc. Soluciones de acondicionamiento para el cuidado de las lentes de contacto duras.
DK1348427T3 (da) 1997-07-29 2008-06-30 Alcon Lab Inc Oftalmiske sammensætninger indeholdende galactomannanpolymerer og borater
JP2000159659A (ja) * 1998-11-30 2000-06-13 Kazuo Tsubota 眼科用人工涙液
US7001615B1 (en) 2001-12-07 2006-02-21 Alcon, Inc. Sustained release ophthalmic, otic and nasal suspension
WO2003059391A2 (en) 2001-12-21 2003-07-24 Alcon, Inc. Viscoelastics for ocular surgery
TW200400055A (en) 2002-02-22 2004-01-01 Pharmacia Corp Ophthalmic formulation with novel gum composition
EP1624858B1 (en) * 2003-04-09 2018-06-06 Rutgers, the State University of New Jersey Novel encochleation methods
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
JP4860475B2 (ja) 2003-06-13 2012-01-25 アルコン，インコーポレイテッド ２種のポリマーの相乗作用的組み合わせを含む眼科用組成物
TWI336257B (en) 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7914803B2 (en) 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5460834A (en) * 1991-12-13 1995-10-24 Alcon Laboratories, Inc. Combinations of polymers for use in physiological tear compositions
US20020123482A1 (en) * 2000-12-21 2002-09-05 Chowhan Masood A. Artificial tear composition containing a combination of three demulcents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI658828B (zh) * 2014-10-31 2019-05-11 中國醫藥大學 用於舒緩及減輕近視之醫藥組合物及其製備方法與用途

Also Published As

Publication number Publication date
EP1633324B1 (en) 2006-12-20
US7244440B2 (en) 2007-07-17
BRPI0411367B1 (pt) 2017-05-02
US7306802B2 (en) 2007-12-11
US7329411B2 (en) 2008-02-12
JP5161950B2 (ja) 2013-03-13
JP4657213B2 (ja) 2011-03-23
JP2006528990A (ja) 2006-12-28
AR047205A1 (es) 2006-01-11
KR20060012023A (ko) 2006-02-06
DE602004003812D1 (de) 2007-02-01
ATE348600T1 (de) 2007-01-15
CN1802148A (zh) 2006-07-12
CY1105877T1 (el) 2011-02-02
CA2527417A1 (en) 2004-12-29
PL1633324T3 (pl) 2007-03-30
US7618620B2 (en) 2009-11-17
WO2004112750A2 (en) 2004-12-29
DE602004003812T2 (de) 2007-04-26
MXPA05013293A (es) 2006-03-09
US20080075687A1 (en) 2008-03-27
EP1633324A2 (en) 2006-03-15
AU2004249136B2 (en) 2009-09-03
ZA200509441B (en) 2007-03-28
PT1633324E (pt) 2007-01-31
JP2011026355A (ja) 2011-02-10
WO2004112750A3 (en) 2005-08-18
TWI336257B (en) 2011-01-21
US20070224159A1 (en) 2007-09-27
CA2527417C (en) 2013-12-03
BRPI0411367A (pt) 2006-07-25
KR101082345B1 (ko) 2011-11-10
US20040253202A1 (en) 2004-12-16
US20070231294A1 (en) 2007-10-04
AU2004249136A1 (en) 2004-12-29
TW200501969A (en) 2005-01-16
DK1633324T3 (da) 2007-04-02
ES2274476T3 (es) 2007-05-16

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Granted publication date: 20071003

Termination date: 20170608

CF01 Termination of patent right due to non-payment of annual fee