KR101082345B1 - 시너지성의 3개의 폴리머 배합물을 포함하는 안과용 조성물 - Google Patents

시너지성의 3개의 폴리머 배합물을 포함하는 안과용 조성물 Download PDF

Info

Publication number
KR101082345B1
KR101082345B1 KR1020057023407A KR20057023407A KR101082345B1 KR 101082345 B1 KR101082345 B1 KR 101082345B1 KR 1020057023407 A KR1020057023407 A KR 1020057023407A KR 20057023407 A KR20057023407 A KR 20057023407A KR 101082345 B1 KR101082345 B1 KR 101082345B1
Authority
KR
South Korea
Prior art keywords
composition
polymer
guar
range
viscosity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020057023407A
Other languages
English (en)
Korean (ko)
Other versions
KR20060012023A (ko
Inventor
마수드 에이 초완
후아강 첸
Original Assignee
알콘, 인코퍼레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알콘, 인코퍼레이티드 filed Critical 알콘, 인코퍼레이티드
Publication of KR20060012023A publication Critical patent/KR20060012023A/ko
Application granted granted Critical
Publication of KR101082345B1 publication Critical patent/KR101082345B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020057023407A 2003-06-13 2004-06-08 시너지성의 3개의 폴리머 배합물을 포함하는 안과용 조성물 Expired - Fee Related KR101082345B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47871303P 2003-06-13 2003-06-13
US60/478,713 2003-06-13
PCT/US2004/018067 WO2004112750A2 (en) 2003-06-13 2004-06-08 Ophthalmic compositions containing a synergistic combination of three polymers

Publications (2)

Publication Number Publication Date
KR20060012023A KR20060012023A (ko) 2006-02-06
KR101082345B1 true KR101082345B1 (ko) 2011-11-10

Family

ID=33539115

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057023407A Expired - Fee Related KR101082345B1 (ko) 2003-06-13 2004-06-08 시너지성의 3개의 폴리머 배합물을 포함하는 안과용 조성물

Country Status (20)

Country Link
US (4) US7244440B2 (enExample)
EP (1) EP1633324B1 (enExample)
JP (2) JP4657213B2 (enExample)
KR (1) KR101082345B1 (enExample)
CN (1) CN100340233C (enExample)
AR (1) AR047205A1 (enExample)
AT (1) ATE348600T1 (enExample)
AU (1) AU2004249136B2 (enExample)
BR (1) BRPI0411367B1 (enExample)
CA (1) CA2527417C (enExample)
CY (1) CY1105877T1 (enExample)
DE (1) DE602004003812T2 (enExample)
DK (1) DK1633324T3 (enExample)
ES (1) ES2274476T3 (enExample)
MX (1) MXPA05013293A (enExample)
PL (1) PL1633324T3 (enExample)
PT (1) PT1633324E (enExample)
TW (1) TWI336257B (enExample)
WO (1) WO2004112750A2 (enExample)
ZA (1) ZA200509441B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
CA2839930C (en) * 2003-06-13 2016-07-05 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
DE602004023516D1 (de) 2003-08-07 2009-11-19 Allergan Inc Zusammensetzungen zur abgabe von therapeutika in die augen und verfahren zu ihrer herstellung und verwendung
EP1749541B1 (en) * 2004-05-27 2014-09-24 Santen Pharmaceutical Co., Ltd Eyedrops
JP2009521493A (ja) * 2005-12-23 2009-06-04 アルコン，インコーポレイテッド 眼への受容体チロシンキナーゼ阻害（ＲＴＫｉ）化合物の送達のための医薬製剤
FR2896152B1 (fr) * 2006-01-17 2016-01-08 Cetem Lab Nouvelles compositions cosmetiques et leur utilisation pour l'application sur les muqueuses
KR20090053892A (ko) 2006-07-25 2009-05-28 오스모티카 코프. 점안액
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
ZA200904917B (en) * 2007-02-09 2010-09-29 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
WO2009021169A2 (en) 2007-08-08 2009-02-12 Lexicon Pharmaceuticals, Inc. (7h-pyrr0l0 [2, 3-d] pyrimidin-4-yl) -piperazines as kinase inhibitors for the treatment of cancer and inflammation
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
CN101977630B (zh) * 2008-03-07 2012-11-21 太阳医药高级研发有限公司 眼药组合物
KR101706391B1 (ko) 2008-04-21 2017-02-13 렉시컨 파마슈티컬스 인코퍼레이티드 Ｌｉｍｋ2 억제제, 그를 포함하는 조성물 및 그의 사용 방법
EP2278954B1 (en) 2008-04-26 2020-08-26 Alcon Inc. Polymeric artificial tear system
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
TWI547522B (zh) * 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
AU2010326099B2 (en) 2009-12-03 2013-03-07 Novartis Ag Carboxyvinyl polymer-container nanoparticle suspensions
JP2013518048A (ja) 2010-01-22 2013-05-20 レクシコン ファーマシューティカルズ インコーポレイテッド 眼の疾患及び障害の治療のための５−（１ｈ−ピラゾール−５−イル）チアゾール系化合物
DE102010009475B4 (de) 2010-02-26 2011-11-24 F. Holzer Gmbh Verfahren zur Herstellung eines dosierbaren applikationsfertigen Präparates
NZ603345A (en) * 2010-05-05 2014-12-24 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations
HUE057140T2 (hu) * 2011-12-07 2022-04-28 Allergan Inc Hatásos lipidszállítás humán könny-filmhez sóérzékeny emulziórendszer alkalmazásával
FR2988297B1 (fr) * 2012-03-22 2014-03-28 Thea Lab Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
TWI658828B (zh) * 2014-10-31 2019-05-11 中國醫藥大學 用於舒緩及減輕近視之醫藥組合物及其製備方法與用途
JP7526718B2 (ja) * 2019-02-27 2024-08-01 参天製薬株式会社 ジクアホソルまたはその塩、ビニル系高分子およびセルロース系高分子を含有する眼科用組成物

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355336A (en) 1966-08-18 1967-11-28 Du Pont Thickened water-bearing inorganic oxidizer salt explosive containing crosslinked galactomannan and polyacrylamide
NL188266C (nl) * 1975-07-29 1992-05-18 Merck & Co Inc Werkwijze ter bereiding van een oogheelkundig inplantaat.
US4039662A (en) * 1975-12-04 1977-08-02 Alcon Laboratories, Inc. Ophthalmic solution
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4767463A (en) 1987-04-15 1988-08-30 Union Carbide Corporation Glycosaminoglycan and cationic polymer combinations
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5368843A (en) 1988-06-08 1994-11-29 Lever Brothers Company, Division Of Conopco, Inc. Thickening system
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5252318A (en) 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
US5460834A (en) * 1991-12-13 1995-10-24 Alcon Laboratories, Inc. Combinations of polymers for use in physiological tear compositions
WO1993017664A1 (en) * 1992-03-02 1993-09-16 Alcon Laboratories, Inc. Combinations of cellulosic polymers and carboxy vinyl polymers and their use in pharmaceutical compositions
CA2134376C (en) * 1993-12-20 2001-10-23 Haresh G. Bhagat Combinations of polymers for use in physiological tear compositions
ATE166227T1 (de) * 1994-03-18 1998-06-15 Senju Pharma Co Sarpogrelat enthaltende opthalmologische zubereitungen zur senkung des intraokularen druckes
US5939485A (en) 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
US6403609B1 (en) * 1997-07-29 2002-06-11 Alcon Manufacturing, Ltd. Ophthalmic compositions containing galactomannan polymers and borate
ATE225392T1 (de) 1997-07-29 2002-10-15 Alcon Lab Inc Konditionierungslösungen für die pflege von harten kontaktlinsen
JP2000159659A (ja) * 1998-11-30 2000-06-13 Kazuo Tsubota 眼科用人工涙液
AR035509A1 (es) * 2000-12-21 2004-06-02 Alcon Inc Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
US7001615B1 (en) 2001-12-07 2006-02-21 Alcon, Inc. Sustained release ophthalmic, otic and nasal suspension
WO2003059391A2 (en) 2001-12-21 2003-07-24 Alcon, Inc. Viscoelastics for ocular surgery
WO2003072081A1 (en) 2002-02-22 2003-09-04 Pharmacia Corporation Ophthalmic formulation with gum system
WO2004091578A2 (en) * 2003-04-09 2004-10-28 Biodelivery Sciences International, Inc. Novel encochleation methods, cochleates and methods of use
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
US7914803B2 (en) * 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
CA2839930C (en) * 2003-06-13 2016-07-05 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers

Also Published As

Publication number Publication date
CA2527417A1 (en) 2004-12-29
CY1105877T1 (el) 2011-02-02
JP2006528990A (ja) 2006-12-28
ZA200509441B (en) 2007-03-28
TW200501969A (en) 2005-01-16
PL1633324T3 (pl) 2007-03-30
US7618620B2 (en) 2009-11-17
AU2004249136B2 (en) 2009-09-03
JP4657213B2 (ja) 2011-03-23
PT1633324E (pt) 2007-01-31
US7244440B2 (en) 2007-07-17
US20070224159A1 (en) 2007-09-27
US20040253202A1 (en) 2004-12-16
WO2004112750A2 (en) 2004-12-29
DE602004003812T2 (de) 2007-04-26
BRPI0411367B1 (pt) 2017-05-02
EP1633324B1 (en) 2006-12-20
CN100340233C (zh) 2007-10-03
US7306802B2 (en) 2007-12-11
TWI336257B (en) 2011-01-21
CA2527417C (en) 2013-12-03
ATE348600T1 (de) 2007-01-15
US7329411B2 (en) 2008-02-12
AR047205A1 (es) 2006-01-11
US20070231294A1 (en) 2007-10-04
DK1633324T3 (da) 2007-04-02
ES2274476T3 (es) 2007-05-16
JP5161950B2 (ja) 2013-03-13
BRPI0411367A (pt) 2006-07-25
CN1802148A (zh) 2006-07-12
EP1633324A2 (en) 2006-03-15
US20080075687A1 (en) 2008-03-27
KR20060012023A (ko) 2006-02-06
WO2004112750A3 (en) 2005-08-18
JP2011026355A (ja) 2011-02-10
AU2004249136A1 (en) 2004-12-29
MXPA05013293A (es) 2006-03-09
DE602004003812D1 (de) 2007-02-01

Similar Documents

Publication Publication Date Title
KR101131056B1 (ko) 시너지성의 2개의 폴리머 배합물을 포함하는 안과용 조성물
KR101082345B1 (ko) 시너지성의 3개의 폴리머 배합물을 포함하는 안과용 조성물
AU2012205283A1 (en) Ophthalmic compositions containing a synergistic combination of two polymers

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20141023

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 20151012

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

FPAY Annual fee payment

Payment date: 20161028

Year of fee payment: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20171105

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20171105