CL2022000080A1 - Edición de ácido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actúa sobre ácido ribonucleico endógeno (adar) utilizando ácidos ribonucleicos (arn) modificados genéticamente - Google Patents

Edición de ácido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actúa sobre ácido ribonucleico endógeno (adar) utilizando ácidos ribonucleicos (arn) modificados genéticamente

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Publication number
CL2022000080A1
CL2022000080A1 CL2022000080A CL2022000080A CL2022000080A1 CL 2022000080 A1 CL2022000080 A1 CL 2022000080A1 CL 2022000080 A CL2022000080 A CL 2022000080A CL 2022000080 A CL2022000080 A CL 2022000080A CL 2022000080 A1 CL2022000080 A1 CL 2022000080A1
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Chile
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rna
ribonucleic acid
ribonucleic
adar
endogenous
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CL2022000080A
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English (en)
Inventor
Wensheng Wei
Liang Qu
Zongyi Yi
Shiyou Zhu
Chunhui Wang
Zhuo Zhou
Feng Tian
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Univ Beijing
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Publication of CL2022000080A1 publication Critical patent/CL2022000080A1/es

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Abstract

La presente solicitud proporciona métodos para editar ARN mediante la introducción de un ARN de reclutamiento de desaminasas en una célula hospedera para la desaminación de una adenosina en un ARN objetivo; la presente solicitud proporciona además ARN de reclutamiento de desaminasas usados en los métodos de edición de ARN y composiciones y kits que comprenden los mismos.
CL2022000080A 2019-07-12 2022-01-11 Edición de ácido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actúa sobre ácido ribonucleico endógeno (adar) utilizando ácidos ribonucleicos (arn) modificados genéticamente CL2022000080A1 (es)

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Application Number Priority Date Filing Date Title
CN2019095802 2019-07-12

Publications (1)

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CL2022000080A1 true CL2022000080A1 (es) 2022-11-18

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CL2022000080A CL2022000080A1 (es) 2019-07-12 2022-01-11 Edición de ácido ribonucleico (arn) dirigido aprovechando la adenosina desaminasa que actúa sobre ácido ribonucleico endógeno (adar) utilizando ácidos ribonucleicos (arn) modificados genéticamente

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US (3) US20220243194A1 (es)
EP (1) EP3997229A1 (es)
JP (1) JP2022536546A (es)
KR (1) KR20220038706A (es)
CN (2) CN117778385A (es)
AU (1) AU2020313143B2 (es)
CA (1) CA3146771A1 (es)
CL (1) CL2022000080A1 (es)
CO (1) CO2022001359A2 (es)
CR (1) CR20220063A (es)
EC (1) ECSP22010372A (es)
IL (1) IL289700A (es)
MX (1) MX2022000497A (es)
PE (1) PE20220300A1 (es)
WO (1) WO2021008447A1 (es)

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