CL2014002524A1 - Composicion farmaceutica que comprende un compuesto activo de formula 1, antagonista de ccr3, dos diluyentes, un aglutinante, un desintegrante y un lubricante; formas de dosificacion en capsula, comprimido o comprimido recubierto con pelicula. - Google Patents

Composicion farmaceutica que comprende un compuesto activo de formula 1, antagonista de ccr3, dos diluyentes, un aglutinante, un desintegrante y un lubricante; formas de dosificacion en capsula, comprimido o comprimido recubierto con pelicula.

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Publication number
CL2014002524A1
CL2014002524A1 CL2014002524A CL2014002524A CL2014002524A1 CL 2014002524 A1 CL2014002524 A1 CL 2014002524A1 CL 2014002524 A CL2014002524 A CL 2014002524A CL 2014002524 A CL2014002524 A CL 2014002524A CL 2014002524 A1 CL2014002524 A1 CL 2014002524A1
Authority
CL
Chile
Prior art keywords
tablet
disintegrant
diluents
capsule
lubricant
Prior art date
Application number
CL2014002524A
Other languages
English (en)
Inventor
Alfred Fetscher
Jochen Matthias Scher
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49292482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2014002524(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of CL2014002524A1 publication Critical patent/CL2014002524A1/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2014002524A 2012-04-04 2014-09-24 Composicion farmaceutica que comprende un compuesto activo de formula 1, antagonista de ccr3, dos diluyentes, un aglutinante, un desintegrante y un lubricante; formas de dosificacion en capsula, comprimido o comprimido recubierto con pelicula. CL2014002524A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12163078 2012-04-04

Publications (1)

Publication Number Publication Date
CL2014002524A1 true CL2014002524A1 (es) 2015-01-23

Family

ID=49292482

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014002524A CL2014002524A1 (es) 2012-04-04 2014-09-24 Composicion farmaceutica que comprende un compuesto activo de formula 1, antagonista de ccr3, dos diluyentes, un aglutinante, un desintegrante y un lubricante; formas de dosificacion en capsula, comprimido o comprimido recubierto con pelicula.

Country Status (30)

Country Link
US (3) US10213421B2 (es)
EP (3) EP3524230B1 (es)
JP (4) JP6320990B2 (es)
KR (2) KR102338465B1 (es)
CN (1) CN104203213A (es)
AR (1) AR090596A1 (es)
AU (1) AU2013245028B2 (es)
BR (1) BR112014024479A8 (es)
CA (1) CA2869058C (es)
CL (1) CL2014002524A1 (es)
CY (1) CY1121137T1 (es)
DK (2) DK2833864T3 (es)
EA (1) EA027627B1 (es)
ES (2) ES2715844T3 (es)
HR (1) HRP20190069T1 (es)
HU (2) HUE041519T2 (es)
IL (1) IL234299A (es)
IN (1) IN2014DN07082A (es)
LT (1) LT2833864T (es)
MX (1) MX358307B (es)
NZ (1) NZ628993A (es)
PH (1) PH12014502241A1 (es)
PL (2) PL2833864T3 (es)
PT (2) PT3524230T (es)
RS (1) RS58360B1 (es)
SI (1) SI2833864T1 (es)
TR (1) TR201821285T4 (es)
TW (1) TW201400115A (es)
UY (1) UY34730A (es)
WO (1) WO2013149987A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
AR090566A1 (es) 2012-04-02 2014-11-19 Boehringer Ingelheim Int Proceso para la produccion de inhibidores de crr
US20130261153A1 (en) * 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) * 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
CN110636844A (zh) * 2017-04-05 2019-12-31 万能溶剂有限公司 使用ccr3-抑制剂治疗衰老相关损伤的方法及组合物
IL269743B (en) 2017-04-05 2022-09-01 Alkahest Inc Methods and preparations for the treatment of disease related to the retina with CCR-3 inhibitor inventions
KR20200067859A (ko) * 2017-10-13 2020-06-12 알카헤스트 인코포레이티드 Ccr3-억제제를 사용한 소양증, 건조증, 및 관련 질환을 치료하기 위한 방법 및 조성물
CN112469439A (zh) 2018-05-15 2021-03-09 万能溶剂有限公司 用白三烯a4水解酶调节剂治疗衰老相关性疾病
EP3856195A4 (en) * 2018-09-26 2022-06-22 Alkahest, Inc. METHODS AND COMPOSITIONS FOR TREATING DISORDERS RELATED TO AGING USING CCR3 INHIBITORS
KR20230056017A (ko) 2020-08-27 2023-04-26 에이지씨 가부시키가이샤 무알칼리 유리 및 유리판
CA3221177A1 (en) 2021-11-01 2023-05-04 Meghan Kerrisk Campbell Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7907121L (sv) 1979-08-27 1981-02-28 Astra Laekemedel Ab Ftalimidinderivat
US4992277A (en) 1989-08-25 1991-02-12 Schering Corporation Immediate release diltiazem formulation
JP2807577B2 (ja) 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
IL116539A (en) * 1995-01-06 2002-02-10 Noven Pharma Preparations given through the skin of unstable anti-acid drugs
JP2001524131A (ja) * 1997-05-09 2001-11-27 セイジ、ファーマスーティカルズ、インク 安定な経口医薬品剤形
CA2318088A1 (en) 1998-01-21 1999-07-29 Yoshisuke Nakasato Chemokine receptor antagonists and methods of use therefor
CA2319781A1 (en) 1998-02-02 1999-08-05 Liping Wang Cyclic amine modulators of chemokine receptor activity
US6140349A (en) 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
SE9802973D0 (sv) 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
EP2305257A1 (en) * 2002-07-08 2011-04-06 ChemGenex Pharmaceuticals, Inc. Amonafide salts and compositions comprising same
EP1668035A2 (en) 2003-09-11 2006-06-14 Critical Therapeutics, Inc. Monoclonal antibodies against hmgb1
AU2004283842A1 (en) 2003-10-24 2005-05-06 F. Hoffmann-La Roche Ag CCR3 receptor antagonists
RU2382037C2 (ru) 2003-11-17 2010-02-20 Бёрингер Ингельхайм Интернациональ Гмбх Новые пиперидинзамещенные индолы или их гетеропроизводные
CN1946402A (zh) 2004-02-05 2007-04-11 先灵公司 用作ccr3拮抗剂的哌啶衍生物
JP2006137718A (ja) 2004-11-12 2006-06-01 Astellas Pharma Inc インドール若しくはインダゾール誘導体
WO2006083390A2 (en) 2004-12-07 2006-08-10 Children's Hospital Medical Center Eotaxin-3 in eosinophilic esophagitis
DOP2006000051A (es) 2005-02-24 2006-08-31 Lilly Co Eli Inhibidores de vegf-r2 y métodos
JP3701964B1 (ja) 2005-03-08 2005-10-05 アステラス製薬株式会社 キヌクリジン誘導体の新規な塩
JP5080450B2 (ja) 2005-04-30 2012-11-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規なピペリジン置換インドール
NL2000323C2 (nl) * 2005-12-20 2007-11-20 Pfizer Ltd Pyrimidine-derivaten.
EP2059515A2 (en) 2006-04-12 2009-05-20 Pfizer Limited Pyrrolidine derivatives as modulators of chemokine ccr5 receptors
WO2008049875A1 (en) 2006-10-27 2008-05-02 Boehringer Ingelheim International Gmbh Novel substituted piperidyl-propane-thiols
WO2008049874A1 (en) 2006-10-27 2008-05-02 Boehringer Ingelheim International Gmbh Piperidyl-propane-thiol ccr3 modulators
GB0701992D0 (en) 2007-02-02 2007-03-14 7Tm Pharma As Grehlin Receptor Modulators
US8008092B2 (en) 2007-10-09 2011-08-30 University Of Kentucky Research Foundation CCR3 inhibition for ocular angiogenesis and macular degeneration
US8530488B2 (en) 2007-10-24 2013-09-10 Generics [Uk] Limited Crystalline forms of bosentan
TW201000446A (en) 2008-05-30 2010-01-01 Astrazeneca Ab New compounds useful in pain therapy
WO2010052727A1 (en) * 2008-11-04 2010-05-14 Ideal Cures Private Limited High performance film coating compositions
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
MX2011011080A (es) 2009-04-22 2012-02-23 Axikin Pharmaceuticals Inc Antagonistas de ccr3 de arilsulfonamida 2, 5-disustituida.
TW201041583A (en) * 2009-04-22 2010-12-01 Axikin Pharmaceuticals Inc 2,5-disubstituted arylsulfonamide CCR3 antagonists
EP2523654A4 (en) * 2010-01-11 2014-08-06 Mohamed Shafee Muneera IMMEDIATE RELEASE COMPOSITIONS OF MEDICAMENTS LABILES ACIDES
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
AR090566A1 (es) 2012-04-02 2014-11-19 Boehringer Ingelheim Int Proceso para la produccion de inhibidores de crr
US20130261153A1 (en) 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) * 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists

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