CL2008002354A1 - Forma cristalina de la sal diclorhidrato de ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((metoxicarbonil)amino)-3-metilbutanoil)-2-pirrolidinil)-1h-imidazol-5-il)-4-bifenilil)-1h-imidazol-2-il)-1-pirrolidinil)carbonil)-2-metilpropil)carbamato de metilo; composición y combinacion farmacéutica; y su uso para tratar la hepatitis c. - Google Patents

Forma cristalina de la sal diclorhidrato de ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((metoxicarbonil)amino)-3-metilbutanoil)-2-pirrolidinil)-1h-imidazol-5-il)-4-bifenilil)-1h-imidazol-2-il)-1-pirrolidinil)carbonil)-2-metilpropil)carbamato de metilo; composición y combinacion farmacéutica; y su uso para tratar la hepatitis c.

Info

Publication number
CL2008002354A1
CL2008002354A1 CL2008002354A CL2008002354A CL2008002354A1 CL 2008002354 A1 CL2008002354 A1 CL 2008002354A1 CL 2008002354 A CL2008002354 A CL 2008002354A CL 2008002354 A CL2008002354 A CL 2008002354A CL 2008002354 A1 CL2008002354 A1 CL 2008002354A1
Authority
CL
Chile
Prior art keywords
imidazol
pyrrolidinyl
crystalline form
methylbutanoyl
methoxycarbonyl
Prior art date
Application number
CL2008002354A
Other languages
English (en)
Spanish (es)
Inventor
Kim Soojin
Gao Qi
Yang Fukang
Original Assignee
Bristol Myers Squibb Holdings Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39739413&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008002354(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Holdings Ireland filed Critical Bristol Myers Squibb Holdings Ireland
Publication of CL2008002354A1 publication Critical patent/CL2008002354A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2008002354A 2007-08-08 2008-08-08 Forma cristalina de la sal diclorhidrato de ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((metoxicarbonil)amino)-3-metilbutanoil)-2-pirrolidinil)-1h-imidazol-5-il)-4-bifenilil)-1h-imidazol-2-il)-1-pirrolidinil)carbonil)-2-metilpropil)carbamato de metilo; composición y combinacion farmacéutica; y su uso para tratar la hepatitis c. CL2008002354A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95459207P 2007-08-08 2007-08-08

Publications (1)

Publication Number Publication Date
CL2008002354A1 true CL2008002354A1 (es) 2009-01-02

Family

ID=39739413

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008002354A CL2008002354A1 (es) 2007-08-08 2008-08-08 Forma cristalina de la sal diclorhidrato de ((1s)-1-(((2s)-2-(5-(4'-(2-((2s)-1-((2s)-2-((metoxicarbonil)amino)-3-metilbutanoil)-2-pirrolidinil)-1h-imidazol-5-il)-4-bifenilil)-1h-imidazol-2-il)-1-pirrolidinil)carbonil)-2-metilpropil)carbamato de metilo; composición y combinacion farmacéutica; y su uso para tratar la hepatitis c.

Country Status (20)

Country Link
US (1) US8629171B2 (https=)
EP (1) EP2183244B1 (https=)
JP (1) JP5244179B2 (https=)
KR (1) KR101508022B1 (https=)
CN (1) CN101778840B (https=)
AR (2) AR070016A1 (https=)
AU (1) AU2008284100B2 (https=)
BR (1) BRPI0815142B8 (https=)
CA (1) CA2695729C (https=)
CL (1) CL2008002354A1 (https=)
CO (1) CO6160327A2 (https=)
EA (1) EA018152B1 (https=)
ES (1) ES2402791T3 (https=)
IL (1) IL203684A (https=)
MX (1) MX2010001368A (https=)
NZ (1) NZ583148A (https=)
PE (1) PE20090940A1 (https=)
TW (1) TWI359813B (https=)
WO (1) WO2009020828A1 (https=)
ZA (1) ZA201000843B (https=)

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EP2183244B1 (en) 2013-01-23
TWI359813B (en) 2012-03-11
CO6160327A2 (es) 2010-05-20
CN101778840B (zh) 2013-11-13
BRPI0815142A2 (pt) 2015-02-03
IL203684A (en) 2014-12-31
CA2695729C (en) 2015-03-31
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ZA201000843B (en) 2011-04-28
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CA2695729A1 (en) 2009-02-12
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HK1144089A1 (en) 2011-01-28
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AR070016A1 (es) 2010-03-10
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EA018152B1 (ru) 2013-05-30
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MX2010001368A (es) 2010-03-01

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