CH672787A5 - - Google Patents

Download PDF

Info

Publication number
CH672787A5
CH672787A5 CH1830/86A CH183086A CH672787A5 CH 672787 A5 CH672787 A5 CH 672787A5 CH 1830/86 A CH1830/86 A CH 1830/86A CH 183086 A CH183086 A CH 183086A CH 672787 A5 CH672787 A5 CH 672787A5
Authority
CH
Switzerland
Prior art keywords
radical
piperazinyl
compound
lower alkyl
hydrogen atom
Prior art date
Application number
CH1830/86A
Other languages
German (de)
English (en)
Inventor
James Stewart New
Joseph P Yevich
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH672787A5 publication Critical patent/CH672787A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH1830/86A 1985-05-06 1986-05-05 CH672787A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73120185A 1985-05-06 1985-05-06

Publications (1)

Publication Number Publication Date
CH672787A5 true CH672787A5 (fr) 1989-12-29

Family

ID=24938510

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1830/86A CH672787A5 (fr) 1985-05-06 1986-05-05

Country Status (25)

Country Link
JP (1) JPH0753728B2 (fr)
KR (1) KR940000829B1 (fr)
CN (1) CN1017901B (fr)
AT (1) AT398572B (fr)
AU (1) AU593244B2 (fr)
BE (1) BE904724A (fr)
CA (1) CA1278792C (fr)
CH (1) CH672787A5 (fr)
DE (1) DE3615180C2 (fr)
DK (1) DK165745C (fr)
EG (1) EG18206A (fr)
ES (6) ES8801250A1 (fr)
FI (1) FI85484C (fr)
FR (1) FR2581385B1 (fr)
GB (1) GB2174703B (fr)
GR (1) GR861149B (fr)
HU (1) HU195509B (fr)
IE (1) IE59201B1 (fr)
IT (1) IT1208607B (fr)
LU (1) LU86421A1 (fr)
MY (1) MY100777A (fr)
NL (1) NL8601146A (fr)
PT (1) PT82523B (fr)
SE (1) SE465270B (fr)
ZA (1) ZA862046B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801186A (en) 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
IE903410A1 (en) * 1989-10-09 1991-04-10 Novo Nordisk As Indole derivatives, their preparation and use
US5272148A (en) * 1992-09-09 1993-12-21 Hoechst-Roussel Pharmaceuticals Incorporated Heteroarenylpiperazines
FR2738824B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 3-(omega(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1 -yl)alkyl)-3,4-dihydroquinazolin-2(1h)-one,leur preparation et leur application en therapeutique
JP3335362B2 (ja) * 1995-09-15 2002-10-15 サノフィ―サンテラボ キノレイン−２（１ｈ）−オン誘導体セロトニンアンタゴニスト
FR2738822B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 4-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)quinolein-2(1h)-one, leur preparation et leur application en therapeutique
FR2738823B1 (fr) * 1995-09-15 1997-10-31 Synthelabo Derives de 3-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)-3,4-dihydroquinolein-2(1h)-one,leur preparation et leur application en therapeutique
FR2761071B1 (fr) * 1997-03-20 1999-12-03 Synthelabo Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique
FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines

Also Published As

Publication number Publication date
JPH0753728B2 (ja) 1995-06-07
GB2174703B (en) 1988-10-26
HU195509B (en) 1988-05-30
ES557757A0 (es) 1988-04-01
EG18206A (en) 1992-09-30
AU5679586A (en) 1986-11-13
ES557855A0 (es) 1989-05-16
DK165745C (da) 1993-06-14
ATA121486A (de) 1994-05-15
DE3615180C2 (de) 1996-03-07
IE861193L (en) 1986-11-06
DE3615180A1 (de) 1986-11-06
SE465270B (sv) 1991-08-19
KR940000829B1 (ko) 1994-02-02
DK207186A (da) 1986-11-07
ES8801250A1 (es) 1987-12-16
DK165745B (da) 1993-01-11
IT8620313A0 (it) 1986-05-06
FI861820A (fi) 1986-11-07
ES557839A0 (es) 1989-01-16
MY100777A (en) 1991-02-14
AU593244B2 (en) 1990-02-08
ZA862046B (en) 1986-11-26
IT1208607B (it) 1989-07-10
SE8602061D0 (sv) 1986-05-05
CN86103071A (zh) 1987-03-18
IE59201B1 (en) 1994-01-26
ES554659A0 (es) 1987-12-16
DK207186D0 (da) 1986-05-05
NL8601146A (nl) 1986-12-01
LU86421A1 (fr) 1986-12-05
HUT43848A (en) 1987-12-28
ES9000005A1 (es) 1989-11-01
FI85484B (fi) 1992-01-15
JPS61268681A (ja) 1986-11-28
ES8900138A1 (es) 1989-01-16
BE904724A (fr) 1986-11-05
PT82523A (en) 1986-06-01
ES8802149A1 (es) 1988-04-01
FR2581385A1 (fr) 1986-11-07
GR861149B (en) 1986-09-09
KR860009008A (ko) 1986-12-19
CN1017901B (zh) 1992-08-19
FI861820A0 (fi) 1986-04-30
CA1278792C (fr) 1991-01-08
FR2581385B1 (fr) 1991-10-04
SE8602061L (sv) 1986-11-07
AT398572B (de) 1994-12-27
FI85484C (fi) 1992-04-27
ES8802614A1 (es) 1988-09-01
ES8900253A1 (es) 1989-05-16
PT82523B (pt) 1988-10-14
GB2174703A (en) 1986-11-12
ES557809A0 (es) 1988-09-01
GB8610810D0 (en) 1986-06-11

Similar Documents

Publication Publication Date Title
DE3433327C2 (de) 1-Heteroaryl-4-[(2,5-pyrrolidindion-1-yl)alkyl]piperazinderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Mittel
DE69615376T2 (de) Piperazin-derivate als heilmittel
DE69232665T2 (de) Neue 4-arylpiperazine und 4-arylpiperidine
DE69010232T2 (de) 2-(1-Piperazinyl)-4-phenylcycloalkanpyridin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten.
DE3423898A1 (de) Piperazinyl-alkyl-1,2,4-triazol-3-on-derivate, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische mittel
DE19724980A1 (de) 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
JPH01249769A (ja) 向精神性ヘテロビシクロアルキルピペラジン誘導体
DE3248138C2 (fr)
EP0647231B1 (fr) Derives n-substitues de 3-azabicyclo[3.2.0]heptane utiles comme agents neuroleptiques, etc.
DE69123315T2 (de) 6,7-Dihydro-3-Phenyl-1,2-benzisoxazol-4(5H)-one und -ole, ein Verfahren für ihre Herstellung und ihre Verwendung als Arzneimittel
DE69006907T2 (de) Arylthiazolylimidazole als 5HT3-Antagonisten.
AT398572B (de) Verfahren zur herstellung neuer disubstituierter 1,4-piperazinylderivate
EP1176144B1 (fr) Dérivés de N-triazolylméthyl-piperazine, en tant qu' antagonistes récepteurs de la neuroquinine
EP1025100B1 (fr) Derives de tetrahydropyridopyrimidinone substitues en position 3, leur production et leur utilisation
AT391698B (de) Verfahren zur herstellung neuer zyklischer imid- derivate von 2-(4-butylpiperazin-1-yl)-pyridinen
EP0409048B1 (fr) 2-Aminothiazoles substitués par un aminoalcoyle et médicaments les contenant
DE69612037T2 (de) Thiopyran Derivate
US4677104A (en) Antipsychotic fused-ring pyridinylpiperazine derivatives
US4529729A (en) Piperazine and homopiperazine compounds
DE19734444A1 (de) 3-Substituierte 3,4,5,7-Tetrahydro-pyrrolo(3',4':4,5) thieno (2,3-d) pyrimidin-Derivate, ihre Herstellung und Verwendung
DE69433005T2 (de) Benzothiazinderivate
DE19746612A1 (de) 2-Substituierte 1,2-Benzisothiazol-Derivate, ihre Herstellung und Verwendung
EP1023296B1 (fr) Derives de pyrido 3',4':4,5]thieno 2,3-d]pyrimidine 3-substitues, leur preparation et leur utilisation
DE3404193C2 (fr)
DE68913167T2 (de) Indol-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate.

Legal Events

Date Code Title Description
PL Patent ceased