CH653670A5 - Benzamid-derivate. - Google Patents

Benzamid-derivate. Download PDF

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Publication number
CH653670A5
CH653670A5 CH1150/83A CH115083A CH653670A5 CH 653670 A5 CH653670 A5 CH 653670A5 CH 1150/83 A CH1150/83 A CH 1150/83A CH 115083 A CH115083 A CH 115083A CH 653670 A5 CH653670 A5 CH 653670A5
Authority
CH
Switzerland
Prior art keywords
aminoethyl
acid addition
formula
compound
compounds
Prior art date
Application number
CH1150/83A
Other languages
German (de)
English (en)
Inventor
Prada Mose Prof Dr Da
Renato Dr Joos
Emilio Dr Kyburz
Pierre Charles Dr Wyss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH1150/83A priority Critical patent/CH653670A5/de
Priority to CA000445296A priority patent/CA1252794A/fr
Priority to NL8400459A priority patent/NL8400459A/nl
Priority to FI840734A priority patent/FI79297C/fi
Priority to IT19778/84A priority patent/IT1173365B/it
Priority to NZ207272A priority patent/NZ207272A/en
Priority to ZA841394A priority patent/ZA841394B/xx
Priority to IL71078A priority patent/IL71078A/xx
Priority to HU84767A priority patent/HU193556B/hu
Priority to AU25066/84A priority patent/AU570431B2/en
Priority to DK147584A priority patent/DK166382C/da
Priority to LU85231A priority patent/LU85231A1/de
Priority to PH30315A priority patent/PH19623A/en
Priority to MC841696A priority patent/MC1568A1/fr
Priority to GR73975A priority patent/GR81866B/el
Priority to DE3407654A priority patent/DE3407654C2/de
Priority to JP59037410A priority patent/JPS59167552A/ja
Priority to FR8403219A priority patent/FR2541996B1/fr
Priority to AT0072484A priority patent/AT390948B/de
Priority to BE0/212488A priority patent/BE899059A/fr
Priority to SE8401190A priority patent/SE466447B/sv
Priority to GB08405486A priority patent/GB2135998B/en
Priority to AR84295901A priority patent/AR243155A1/es
Priority to PT78187A priority patent/PT78187B/pt
Priority to NO840797A priority patent/NO165999C/no
Priority to ES530230A priority patent/ES8504680A1/es
Priority to IE512/84A priority patent/IE57004B1/en
Priority to KR1019840001083A priority patent/KR910008202B1/ko
Priority to ES537045A priority patent/ES8506600A1/es
Priority to ES537046A priority patent/ES8506601A1/es
Publication of CH653670A5 publication Critical patent/CH653670A5/de
Priority to AU83079/87A priority patent/AU609758B2/en
Priority to US07/896,747 priority patent/US5238962A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1150/83A 1983-03-03 1983-03-03 Benzamid-derivate. CH653670A5 (de)

Priority Applications (32)

Application Number Priority Date Filing Date Title
CH1150/83A CH653670A5 (de) 1983-03-03 1983-03-03 Benzamid-derivate.
CA000445296A CA1252794A (fr) 1983-03-03 1984-01-13 Derives de benzamide
NL8400459A NL8400459A (nl) 1983-03-03 1984-02-13 Benzamidederivaten.
FI840734A FI79297C (fi) 1983-03-03 1984-02-22 Foerfarande foer framstaellning av farmakologiskt aktiva benzamidderivat.
IT19778/84A IT1173365B (it) 1983-03-03 1984-02-23 Derivati di benzammidi
NZ207272A NZ207272A (en) 1983-03-03 1984-02-24 Benzamide derivatives and pharmaceutical compositions
ZA841394A ZA841394B (en) 1983-03-03 1984-02-24 Benzamide derivatives
IL71078A IL71078A (en) 1983-03-03 1984-02-27 Pharmaceutical compositions comprising n-aminoethyl-benzamide derivatives,certain such novel compounds and their preparation
HU84767A HU193556B (en) 1983-03-03 1984-02-27 Process for preparing benzamide derivatives
AU25066/84A AU570431B2 (en) 1983-03-03 1984-02-27 Benzamide derivatives
DK147584A DK166382C (da) 1983-03-03 1984-02-29 Benzamid-derivater, deres fremstilling og laegemidler indeholdende disse
LU85231A LU85231A1 (de) 1983-03-03 1984-02-29 Benzamid-derivate
PH30315A PH19623A (fr) 1983-03-03 1984-02-29
DE3407654A DE3407654C2 (de) 1983-03-03 1984-03-01 Verwendung von Benzamid-Derivaten
GR73975A GR81866B (fr) 1983-03-03 1984-03-01
MC841696A MC1568A1 (fr) 1983-03-03 1984-03-01 Derives de benzamide
JP59037410A JPS59167552A (ja) 1983-03-03 1984-03-01 ベンズアミド誘導体
FR8403219A FR2541996B1 (fr) 1983-03-03 1984-03-01 Derives de benzamide
AR84295901A AR243155A1 (es) 1983-03-03 1984-03-02 Procedimiento para la preparacion de nuevas benzamidas n-aminoetil-sustituidas.
ES530230A ES8504680A1 (es) 1983-03-03 1984-03-02 Un procedimiento para la preparacion de derivados de benzamida
SE8401190A SE466447B (sv) 1983-03-03 1984-03-02 N-aminoetylbensamidderivat samt farmaceutiska preparat daerav
GB08405486A GB2135998B (en) 1983-03-03 1984-03-02 Benzamide derivatives
AT0072484A AT390948B (de) 1983-03-03 1984-03-02 Verfahren zur herstellung von neuen benzamid-derivaten
PT78187A PT78187B (en) 1983-03-03 1984-03-02 Process for preparing benzamide derivatives and of pharmaceutical compositions containing the same
NO840797A NO165999C (no) 1983-03-03 1984-03-02 Analogifremgangsmaate til fremstilling av terapeutisk aktive n-(2-aminoetyl)benzamid-derivater.
BE0/212488A BE899059A (fr) 1983-03-03 1984-03-02 Derives de benzamide
IE512/84A IE57004B1 (en) 1983-03-03 1984-03-02 Benzamide derivatives
KR1019840001083A KR910008202B1 (ko) 1983-03-03 1984-03-03 벤즈아미드 유도체의 제조방법
ES537045A ES8506600A1 (es) 1983-03-03 1984-10-25 Un procedimiento para la preparacion de derivados de benzamida
ES537046A ES8506601A1 (es) 1983-03-03 1984-10-25 Un procedimiento para la preparacion de derivados de benzamida
AU83079/87A AU609758B2 (en) 1983-03-03 1987-12-24 Benzamide derivatives
US07/896,747 US5238962A (en) 1983-03-03 1992-06-09 Benzamide derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1150/83A CH653670A5 (de) 1983-03-03 1983-03-03 Benzamid-derivate.

Publications (1)

Publication Number Publication Date
CH653670A5 true CH653670A5 (de) 1986-01-15

Family

ID=4203649

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1150/83A CH653670A5 (de) 1983-03-03 1983-03-03 Benzamid-derivate.

Country Status (28)

Country Link
JP (1) JPS59167552A (fr)
KR (1) KR910008202B1 (fr)
AR (1) AR243155A1 (fr)
AT (1) AT390948B (fr)
AU (2) AU570431B2 (fr)
BE (1) BE899059A (fr)
CA (1) CA1252794A (fr)
CH (1) CH653670A5 (fr)
DE (1) DE3407654C2 (fr)
DK (1) DK166382C (fr)
ES (3) ES8504680A1 (fr)
FI (1) FI79297C (fr)
FR (1) FR2541996B1 (fr)
GB (1) GB2135998B (fr)
GR (1) GR81866B (fr)
HU (1) HU193556B (fr)
IE (1) IE57004B1 (fr)
IL (1) IL71078A (fr)
IT (1) IT1173365B (fr)
LU (1) LU85231A1 (fr)
MC (1) MC1568A1 (fr)
NL (1) NL8400459A (fr)
NO (1) NO165999C (fr)
NZ (1) NZ207272A (fr)
PH (1) PH19623A (fr)
PT (1) PT78187B (fr)
SE (1) SE466447B (fr)
ZA (1) ZA841394B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1261335A (fr) * 1984-08-29 1989-09-26 Hoffmann-La Roche Limited/Hoffmann-La Roche Limitee Derives d'ethylenediamine-monoamides
US4772630A (en) * 1984-11-23 1988-09-20 Ciba-Geigy Corp. Benzamides and their salts
NZ219974A (en) * 1986-04-22 1989-08-29 Goedecke Ag N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases
FR2642972B1 (fr) * 1989-02-14 1994-08-05 Inst Nat Sante Rech Med Agents pour le diagnostic et le traitement des melanomes, derives halogenes aromatiques utilisables comme de tels agents et leur preparation
WO2014155184A1 (fr) * 2013-03-28 2014-10-02 Rhenovia Pharma Traitement pour maladie de parkinson

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342679A (en) * 1967-09-19 Parts by weight of acid chloride to react with parts of amine in
FR6557M (fr) * 1967-06-20 1968-12-23 Ile De France
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
GB1520584A (en) * 1975-04-02 1978-08-09 Yamanouchi Pharma Co Ltd 2 - alkoxy - 5 substituted benzamide derivatives and their use in pharmaceutical compositions
DE2616486A1 (de) * 1976-04-14 1977-11-03 Basf Ag Farbstoffe der perylentetracarbonsaeurediimidreihe
CA1206964A (fr) * 1980-11-12 1986-07-02 Nobuo Shinma Derives tetrasubstitues du benzene
DE3200258A1 (de) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Substituierte 1-benzoyl-2-phenylimino-imidazolidine, deren saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende arzneimittel
IL69997A0 (en) * 1983-01-03 1984-01-31 Miles Lab Procainamide and n-acetylprocainamide immunogens,antibodies prepared therefrom,labeled conjugates,and the use of such antibodies and labeled conjugates in immunoassays
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides

Also Published As

Publication number Publication date
NO165999C (no) 1991-05-15
KR840009077A (ko) 1984-12-24
HU193556B (en) 1987-10-28
DK166382B (da) 1993-05-10
GB8405486D0 (en) 1984-04-04
FR2541996A1 (fr) 1984-09-07
IL71078A (en) 1987-12-31
KR910008202B1 (ko) 1991-10-11
MC1568A1 (fr) 1985-02-04
DK166382C (da) 1993-09-27
SE466447B (sv) 1992-02-17
ES537046A0 (es) 1985-08-16
CA1252794A (fr) 1989-04-18
AU2506684A (en) 1984-09-06
JPH0430389B2 (fr) 1992-05-21
NO840797L (no) 1984-09-04
PH19623A (fr) 1986-06-04
AU8307987A (en) 1988-06-16
ES530230A0 (es) 1985-05-01
GR81866B (fr) 1984-12-12
DK147584A (da) 1984-09-04
PT78187B (en) 1986-08-05
JPS59167552A (ja) 1984-09-21
FI79297B (fi) 1989-08-31
IE840512L (en) 1984-09-03
IT1173365B (it) 1987-06-24
AR243155A1 (es) 1993-07-30
NZ207272A (en) 1987-07-31
SE8401190D0 (sv) 1984-03-02
AT390948B (de) 1990-07-25
ES537045A0 (es) 1985-08-16
ES8504680A1 (es) 1985-05-01
ES8506601A1 (es) 1985-08-16
DK147584D0 (da) 1984-02-29
FI79297C (fi) 1989-12-11
ZA841394B (en) 1985-06-26
FI840734A0 (fi) 1984-02-22
NL8400459A (nl) 1984-10-01
IE57004B1 (en) 1992-03-11
DE3407654A1 (de) 1984-09-06
SE8401190L (sv) 1984-09-04
AU570431B2 (en) 1988-03-17
ATA72484A (de) 1990-01-15
PT78187A (en) 1984-04-01
NO165999B (no) 1991-02-04
LU85231A1 (de) 1985-09-12
IT8419778A0 (it) 1984-02-23
FR2541996B1 (fr) 1987-12-11
BE899059A (fr) 1984-09-03
GB2135998B (en) 1986-09-24
AU609758B2 (en) 1991-05-09
DE3407654C2 (de) 1994-04-07
FI840734A (fi) 1984-09-04
ES8506600A1 (es) 1985-08-16
GB2135998A (en) 1984-09-12
IL71078A0 (en) 1984-05-31

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Owner name: F. HOFFMANN-LA ROCHE AG

PL Patent ceased