CH653037A5 - Ribonukleotide von clindamycinanalogen, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel. - Google Patents

Ribonukleotide von clindamycinanalogen, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel. Download PDF

Info

Publication number
CH653037A5
CH653037A5 CH2386/82A CH238682A CH653037A5 CH 653037 A5 CH653037 A5 CH 653037A5 CH 2386/82 A CH2386/82 A CH 2386/82A CH 238682 A CH238682 A CH 238682A CH 653037 A5 CH653037 A5 CH 653037A5
Authority
CH
Switzerland
Prior art keywords
avg
formula
compound
halogen
optionally substituted
Prior art date
Application number
CH2386/82A
Other languages
German (de)
English (en)
Inventor
Alexander Demetrios Argoudelis
David Womack Stroman
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/255,541 external-priority patent/US4368193A/en
Priority claimed from US06/255,542 external-priority patent/US4383109A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CH653037A5 publication Critical patent/CH653037A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/305—Pyrimidine nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
CH2386/82A 1981-04-20 1982-04-20 Ribonukleotide von clindamycinanalogen, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel. CH653037A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/255,541 US4368193A (en) 1981-04-20 1981-04-20 Process for treating malaria
US06/255,542 US4383109A (en) 1981-04-20 1981-04-20 Lincomycin nucleotides

Publications (1)

Publication Number Publication Date
CH653037A5 true CH653037A5 (de) 1985-12-13

Family

ID=26944757

Family Applications (1)

Application Number Title Priority Date Filing Date
CH2386/82A CH653037A5 (de) 1981-04-20 1982-04-20 Ribonukleotide von clindamycinanalogen, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel.

Country Status (15)

Country Link
KR (1) KR880002416B1 (es)
AU (1) AU545748B2 (es)
CA (1) CA1163938A (es)
CH (1) CH653037A5 (es)
DE (1) DE3213921A1 (es)
ES (1) ES8308927A1 (es)
FR (1) FR2504142B1 (es)
GB (1) GB2097002B (es)
HU (1) HU191085B (es)
IL (1) IL65385A (es)
IT (1) IT1151719B (es)
NL (1) NL8201595A (es)
PL (1) PL133485B1 (es)
SE (1) SE459861B (es)
SU (1) SU1303036A3 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3671647A (en) * 1971-03-24 1972-06-20 Upjohn Co Lincomycin 3-nucleotides and the salts thereof

Also Published As

Publication number Publication date
FR2504142B1 (fr) 1985-07-26
SE8202433L (sv) 1982-10-21
NL8201595A (nl) 1982-11-16
KR830010195A (ko) 1983-12-26
GB2097002B (en) 1985-06-19
AU545748B2 (en) 1985-08-01
PL236043A1 (es) 1982-11-08
FR2504142A1 (fr) 1982-10-22
SU1303036A3 (ru) 1987-04-07
DE3213921A1 (de) 1983-01-05
AU8198882A (en) 1982-10-28
KR880002416B1 (ko) 1988-11-08
SE459861B (sv) 1989-08-14
ES511499A0 (es) 1983-10-01
IL65385A0 (en) 1982-05-31
PL133485B1 (en) 1985-06-29
ES8308927A1 (es) 1983-10-01
GB2097002A (en) 1982-10-27
HU191085B (en) 1987-01-28
IT8220810A0 (it) 1982-04-19
IL65385A (en) 1985-10-31
IT1151719B (it) 1986-12-24
CA1163938A (en) 1984-03-20

Similar Documents

Publication Publication Date Title
CH647527A5 (de) Salz von 1,1-dioxopenicillanoyloxymethyl-6-(d-alpha-amino-alpha-phenylacetamido)-penicillanat, verfahren zu dessen herstellung sowie dieses salz enthaltende pharmazeutische praeparate.
CH685189A5 (de) Ultramikroemulsionen aus spontan dispergierbaren Konzentraten mit antitumoral wirksamen Xanthophyll-Estern.
DD145059A5 (de) Verfahren zur herstellung einer antibakteriellen zusammensetzung
DE3320342A1 (de) Reine einzelne faktoren 1, 2, 3, 4 und 5 von teichomycin a(pfeil abwaerts)2(pfeil abwaerts) und verfahren zu ihrer herstellung
CH681153A5 (de) Neue sterolester- und sterolphosphorverbindungen.
DE3043502A1 (de) Analoga von lincomycin und clindamycin
DE2462691C2 (es)
EP0550704B1 (de) BIOTENSIDE ESTER MIT VITAMIN-D-VERBINDUNGEN; IHRE HERSTELLUNG UND AUFARBEITUNG ZU SPONTAN DISPERGIERBAREN kONZENTRATEN, SOWIE IHRE VERWENDUNG ZUR BEHANDLUNG VON TUMOREN
DE2112057A1 (de) Neue Penicillinester
DE2135543A1 (de) Benzthiazolderivate enthaltende arzneimittel
CH653037A5 (de) Ribonukleotide von clindamycinanalogen, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel.
DE2708493C2 (de) Antibiotikum AM-1042
DE3509949C2 (de) Verbindungen und deren Verwendung zur Behandlung von Protozoeninfektionen
DE10111682B4 (de) Caloporosid-Derivate, Verfahren zu deren Herstellung und deren Verwendung
EP0636618A1 (de) Spontan dispergierbare Konzentrate und Mikroemulsionen mit Vitamin-E-Verbindungen zur Herstellung von Arzneimitteln mit Antitumoraler Wirksamkeit
DE3041130C2 (es)
DE69913369T2 (de) Mikrobielle transformationsprodukte
EP0105393B1 (de) Neue Nucleosidverbindungen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2907976A1 (de) Neue lonomycinderivate
DE3147311C2 (es)
EP0205077A2 (de) Suramin-Natrium zur Verwendung als Immunstimulans
EP0848064B1 (de) Neues Antibiotikum, Feglymycin, Verfahren zu seiner Herstellung und Verwendung
EP0196330B1 (de) Verwendung von pyrrothinderivaten
EP0150719B1 (de) Substituierte Salicylsäureamide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2525095C2 (de) Polyetherantibiotika A-28086 A, B und D, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Futtermittel

Legal Events

Date Code Title Description
PL Patent ceased