CH651036A5 - 1-benzyl-4-(4-(2-pyrimidinylamino)-benzyl)-2,3-dioxopiperazin-derivate, salze derselben, verfahren zur herstellung derselben und carcinostatische mittel mit einem gehalt derselben. - Google Patents

1-benzyl-4-(4-(2-pyrimidinylamino)-benzyl)-2,3-dioxopiperazin-derivate, salze derselben, verfahren zur herstellung derselben und carcinostatische mittel mit einem gehalt derselben. Download PDF

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Publication number
CH651036A5
CH651036A5 CH674/82A CH67482A CH651036A5 CH 651036 A5 CH651036 A5 CH 651036A5 CH 674/82 A CH674/82 A CH 674/82A CH 67482 A CH67482 A CH 67482A CH 651036 A5 CH651036 A5 CH 651036A5
Authority
CH
Switzerland
Prior art keywords
benzyl
formula
compound
substituted
dioxopiperazine
Prior art date
Application number
CH674/82A
Other languages
German (de)
English (en)
Inventor
Takako Hori
Chosaku Yoshida
Yasuo Kiba
Ryuko Takeno
Joji Nakano
Jun Nitta
Sumiko Kishimoto
Shohachi Murakami
Hisatsugu Tsuda
Isamu Saikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of CH651036A5 publication Critical patent/CH651036A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH674/82A 1981-02-06 1982-02-04 1-benzyl-4-(4-(2-pyrimidinylamino)-benzyl)-2,3-dioxopiperazin-derivate, salze derselben, verfahren zur herstellung derselben und carcinostatische mittel mit einem gehalt derselben. CH651036A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56015837A JPS57140783A (en) 1981-02-06 1981-02-06 1-benzyl-4-(4-(2-pyrimidinylamino)benzyl)-2, 3-dioxopiperazine derivative and its salt, their preparation, and carcinostatic agent containing the same

Publications (1)

Publication Number Publication Date
CH651036A5 true CH651036A5 (de) 1985-08-30

Family

ID=11899943

Family Applications (1)

Application Number Title Priority Date Filing Date
CH674/82A CH651036A5 (de) 1981-02-06 1982-02-04 1-benzyl-4-(4-(2-pyrimidinylamino)-benzyl)-2,3-dioxopiperazin-derivate, salze derselben, verfahren zur herstellung derselben und carcinostatische mittel mit einem gehalt derselben.

Country Status (12)

Country Link
JP (1) JPS57140783A (hu)
KR (1) KR880001105B1 (hu)
AU (1) AU537512B2 (hu)
BE (1) BE892032A (hu)
CH (1) CH651036A5 (hu)
DE (1) DE3204074A1 (hu)
ES (2) ES8304970A1 (hu)
FR (1) FR2499569A1 (hu)
GB (1) GB2094296B (hu)
IT (1) IT1154274B (hu)
NL (1) NL8200451A (hu)
SE (1) SE449101B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU742388B2 (en) * 1996-12-24 2002-01-03 Chugai Seiyaku Kabushiki Kaisha Aromatic amine derivatives having nos inhibiting action
US11542222B2 (en) * 2018-04-11 2023-01-03 Mitsubishi Gas Chemical Company, Inc. Method for preparing dicyanoalkane and bis(aminomethyl) alkane

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5618969A (en) * 1979-07-24 1981-02-23 Toyama Chem Co Ltd Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation

Also Published As

Publication number Publication date
BE892032A (fr) 1982-08-05
SE449101B (sv) 1987-04-06
GB2094296A (en) 1982-09-15
FR2499569A1 (fr) 1982-08-13
IT8247729A0 (it) 1982-02-05
JPS57140783A (en) 1982-08-31
GB2094296B (en) 1985-02-13
SE8200679L (sv) 1982-09-22
FR2499569B1 (hu) 1985-02-22
AU537512B2 (en) 1984-06-28
JPS6366319B2 (hu) 1988-12-20
KR830009090A (ko) 1983-12-17
IT1154274B (it) 1987-01-21
NL8200451A (nl) 1982-09-01
ES8402285A1 (es) 1984-01-16
ES509391A0 (es) 1983-03-16
ES518304A0 (es) 1984-01-16
AU8024082A (en) 1982-08-12
ES8304970A1 (es) 1983-03-16
DE3204074C2 (hu) 1987-12-23
DE3204074A1 (de) 1982-10-28
KR880001105B1 (ko) 1988-06-29

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