CH638521A5 - Process for obtaining the antibiotic thienamycin - Google Patents

Process for obtaining the antibiotic thienamycin Download PDF

Info

Publication number
CH638521A5
CH638521A5 CH204578A CH204578A CH638521A5 CH 638521 A5 CH638521 A5 CH 638521A5 CH 204578 A CH204578 A CH 204578A CH 204578 A CH204578 A CH 204578A CH 638521 A5 CH638521 A5 CH 638521A5
Authority
CH
Switzerland
Prior art keywords
liquid
antibiotic
solvent
exchangers
thienamycin
Prior art date
Application number
CH204578A
Other languages
German (de)
English (en)
Inventor
Rathin Datta
George Thomas Wildman
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH638521A5 publication Critical patent/CH638521A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02Preparation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH204578A 1977-03-01 1978-02-24 Process for obtaining the antibiotic thienamycin CH638521A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77335477A 1977-03-01 1977-03-01

Publications (1)

Publication Number Publication Date
CH638521A5 true CH638521A5 (en) 1983-09-30

Family

ID=25097982

Family Applications (1)

Application Number Title Priority Date Filing Date
CH204578A CH638521A5 (en) 1977-03-01 1978-02-24 Process for obtaining the antibiotic thienamycin

Country Status (11)

Country Link
JP (1) JPS53107483A (pt)
CH (1) CH638521A5 (pt)
DE (1) DE2808636A1 (pt)
DK (1) DK144097C (pt)
ES (1) ES467309A1 (pt)
FR (1) FR2382453A1 (pt)
GB (1) GB1568924A (pt)
IT (1) IT1103481B (pt)
NL (1) NL7801756A (pt)
PT (1) PT67721A (pt)
SE (1) SE7801695L (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024447B1 (en) * 1979-08-28 1983-07-20 Merck & Co. Inc. Process for purifying thienamycin
DE3146190A1 (de) * 1981-11-21 1983-06-16 Hoechst Ag, 6230 Frankfurt Isolierung von chemisch instabilen antibiotika aus fermentationsloesungen

Also Published As

Publication number Publication date
GB1568924A (en) 1980-06-11
SE7801695L (sv) 1978-09-02
PT67721A (en) 1978-04-01
FR2382453A1 (fr) 1978-09-29
DE2808636A1 (de) 1978-09-07
IT7848188A0 (it) 1978-02-24
IT1103481B (it) 1985-10-14
JPS53107483A (en) 1978-09-19
DK144097B (da) 1981-12-07
FR2382453B1 (pt) 1982-11-19
NL7801756A (nl) 1978-09-05
DK144097C (da) 1982-05-17
ES467309A1 (es) 1979-08-16
DK67478A (da) 1978-09-02

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Legal Events

Date Code Title Description
PL Patent ceased