ES467309A1 - Procedimiento quimico - Google Patents
Procedimiento quimicoInfo
- Publication number
- ES467309A1 ES467309A1 ES467309A ES467309A ES467309A1 ES 467309 A1 ES467309 A1 ES 467309A1 ES 467309 A ES467309 A ES 467309A ES 467309 A ES467309 A ES 467309A ES 467309 A1 ES467309 A1 ES 467309A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiotic
- thienamycin
- ion exchanger
- liquid ion
- brought
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WKDDRNSBRWANNC-ATRFCDNQSA-N Thienamycin Chemical compound C1C(SCCN)=C(C(O)=O)N2C(=O)[C@H]([C@H](O)C)[C@H]21 WKDDRNSBRWANNC-ATRFCDNQSA-N 0.000 title abstract 4
- WKDDRNSBRWANNC-UHFFFAOYSA-N Thienamycin Natural products C1C(SCCN)=C(C(O)=O)N2C(=O)C(C(O)C)C21 WKDDRNSBRWANNC-UHFFFAOYSA-N 0.000 title abstract 4
- 238000011084 recovery Methods 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 abstract 5
- 239000007788 liquid Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000012062 aqueous buffer Substances 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
- C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Las caldos de fermentación o soluciones impuras que contienen tienamicina, una sustancia con actividad antibiótica contra microorganismos gram-negativos y gram-positivos se aíslan utilizando sistemas líquidos cambiadores de ión.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77335477A | 1977-03-01 | 1977-03-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES467309A1 true ES467309A1 (es) | 1979-08-16 |
Family
ID=25097982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES467309A Expired ES467309A1 (es) | 1977-03-01 | 1978-02-24 | Procedimiento quimico |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS53107483A (es) |
| CH (1) | CH638521A5 (es) |
| DE (1) | DE2808636A1 (es) |
| DK (1) | DK144097C (es) |
| ES (1) | ES467309A1 (es) |
| FR (1) | FR2382453A1 (es) |
| GB (1) | GB1568924A (es) |
| IT (1) | IT1103481B (es) |
| NL (1) | NL7801756A (es) |
| PT (1) | PT67721A (es) |
| SE (1) | SE7801695L (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0024447B1 (en) * | 1979-08-28 | 1983-07-20 | Merck & Co. Inc. | Process for purifying thienamycin |
| DE3146190A1 (de) * | 1981-11-21 | 1983-06-16 | Hoechst Ag, 6230 Frankfurt | Isolierung von chemisch instabilen antibiotika aus fermentationsloesungen |
-
1978
- 1978-02-14 SE SE7801695A patent/SE7801695L/xx unknown
- 1978-02-15 DK DK67478A patent/DK144097C/da not_active IP Right Cessation
- 1978-02-16 NL NL7801756A patent/NL7801756A/xx not_active Application Discontinuation
- 1978-02-24 IT IT48188/78A patent/IT1103481B/it active
- 1978-02-24 ES ES467309A patent/ES467309A1/es not_active Expired
- 1978-02-24 CH CH204578A patent/CH638521A5/de not_active IP Right Cessation
- 1978-02-27 GB GB7719/78A patent/GB1568924A/en not_active Expired
- 1978-02-27 FR FR7805531A patent/FR2382453A1/fr active Granted
- 1978-02-28 DE DE19782808636 patent/DE2808636A1/de not_active Withdrawn
- 1978-03-01 JP JP2215478A patent/JPS53107483A/ja active Pending
- 1978-03-01 PT PT67721A patent/PT67721A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1568924A (en) | 1980-06-11 |
| SE7801695L (sv) | 1978-09-02 |
| PT67721A (en) | 1978-04-01 |
| FR2382453A1 (fr) | 1978-09-29 |
| DE2808636A1 (de) | 1978-09-07 |
| IT7848188A0 (it) | 1978-02-24 |
| IT1103481B (it) | 1985-10-14 |
| CH638521A5 (en) | 1983-09-30 |
| JPS53107483A (en) | 1978-09-19 |
| DK144097B (da) | 1981-12-07 |
| FR2382453B1 (es) | 1982-11-19 |
| NL7801756A (nl) | 1978-09-05 |
| DK144097C (da) | 1982-05-17 |
| DK67478A (da) | 1978-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |