JPS54160795A - Preparation of gentamicin c/a - Google Patents

Preparation of gentamicin c/a

Info

Publication number
JPS54160795A
JPS54160795A JP6948478A JP6948478A JPS54160795A JP S54160795 A JPS54160795 A JP S54160795A JP 6948478 A JP6948478 A JP 6948478A JP 6948478 A JP6948478 A JP 6948478A JP S54160795 A JPS54160795 A JP S54160795A
Authority
JP
Japan
Prior art keywords
micromonospora
sisomicin
gentamicin
gram
converting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6948478A
Other languages
Japanese (ja)
Other versions
JPS5849237B2 (en
Inventor
Kiyoshi Nakayama
Hiroshi Kase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP6948478A priority Critical patent/JPS5849237B2/en
Publication of JPS54160795A publication Critical patent/JPS54160795A/en
Publication of JPS5849237B2 publication Critical patent/JPS5849237B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare gentamicin C/a (an antibiotic effective to Gram-positive and Gram-negative bacteria), in high yield and in a short time, by the use of specific microorganisms capable of converting sisomicin to gentamicin C/a.
CONSTITUTION: Microorganisms belonging to Micromonospora genus and capable of converting sisomicin into gentamicin C/a, e.g. Micromonospora sagamiensis ATCC21803, Micromonospora purpurea ATCC31119, Micromonospora purpurea ATCC15835, Micromonospora echinospora ATCC15837, etc., or their treated product (e.g. disintegrated and extracted product) are brought into contact with sisomicin (e.g. by culturing the above microorganisms in a medium containing sisomicin).
COPYRIGHT: (C)1979,JPO&Japio
JP6948478A 1978-06-09 1978-06-09 Method for producing dientamicin C/a Expired JPS5849237B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6948478A JPS5849237B2 (en) 1978-06-09 1978-06-09 Method for producing dientamicin C/a

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6948478A JPS5849237B2 (en) 1978-06-09 1978-06-09 Method for producing dientamicin C/a

Publications (2)

Publication Number Publication Date
JPS54160795A true JPS54160795A (en) 1979-12-19
JPS5849237B2 JPS5849237B2 (en) 1983-11-02

Family

ID=13404015

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6948478A Expired JPS5849237B2 (en) 1978-06-09 1978-06-09 Method for producing dientamicin C/a

Country Status (1)

Country Link
JP (1) JPS5849237B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102363759A (en) * 2011-10-27 2012-02-29 福州大学 Engineering bacteria for producing gentamicin C1a and application thereof
CN110563782A (en) * 2019-09-29 2019-12-13 常州方圆制药有限公司 Gentamicin C1aPurification method of (2)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102363759A (en) * 2011-10-27 2012-02-29 福州大学 Engineering bacteria for producing gentamicin C1a and application thereof
CN110563782A (en) * 2019-09-29 2019-12-13 常州方圆制药有限公司 Gentamicin C1aPurification method of (2)
CN110563782B (en) * 2019-09-29 2022-08-30 常州方圆制药有限公司 Gentamicin C 1a Purification method of (2)

Also Published As

Publication number Publication date
JPS5849237B2 (en) 1983-11-02

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