CH638482A5 - Process for enlarging an enantiomeric portion of the acid constituent of a salt of a 2-arylpropionic acid - Google Patents

Process for enlarging an enantiomeric portion of the acid constituent of a salt of a 2-arylpropionic acid Download PDF

Info

Publication number
CH638482A5
CH638482A5 CH249378A CH249378A CH638482A5 CH 638482 A5 CH638482 A5 CH 638482A5 CH 249378 A CH249378 A CH 249378A CH 249378 A CH249378 A CH 249378A CH 638482 A5 CH638482 A5 CH 638482A5
Authority
CH
Switzerland
Prior art keywords
salt
acid
ethylamine
diluent
enantiomer
Prior art date
Application number
CH249378A
Other languages
German (de)
English (en)
Inventor
John Stuart Nicholson
James Gordon Tantum
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9697/77A external-priority patent/GB1596032A/en
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of CH638482A5 publication Critical patent/CH638482A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH249378A 1977-03-08 1978-03-07 Process for enlarging an enantiomeric portion of the acid constituent of a salt of a 2-arylpropionic acid CH638482A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9697/77A GB1596032A (en) 1977-03-08 1977-03-08 Resolution of optically active 2-arylpropionic acids
GB194678 1978-01-18

Publications (1)

Publication Number Publication Date
CH638482A5 true CH638482A5 (en) 1983-09-30

Family

ID=26237091

Family Applications (1)

Application Number Title Priority Date Filing Date
CH249378A CH638482A5 (en) 1977-03-08 1978-03-07 Process for enlarging an enantiomeric portion of the acid constituent of a salt of a 2-arylpropionic acid

Country Status (29)

Country Link
JP (1) JPS53112841A (da)
AT (1) AT360508B (da)
AU (1) AU521708B2 (da)
BG (1) BG28567A3 (da)
CA (1) CA1105942A (da)
CH (1) CH638482A5 (da)
CS (1) CS222255B2 (da)
DD (1) DD136261A5 (da)
DE (1) DE2809794A1 (da)
DK (1) DK154418C (da)
EG (1) EG13345A (da)
ES (1) ES467606A1 (da)
FI (1) FI66828C (da)
FR (1) FR2383155A1 (da)
GR (1) GR64816B (da)
HU (1) HU178810B (da)
IE (1) IE46476B1 (da)
IN (1) IN147834B (da)
IT (1) IT1202818B (da)
LU (1) LU79186A1 (da)
NL (1) NL189126C (da)
NO (1) NO146197C (da)
NZ (1) NZ186644A (da)
PH (1) PH13333A (da)
PL (1) PL110888B1 (da)
PT (1) PT67743A (da)
SE (1) SE436422B (da)
SU (1) SU784759A3 (da)
YU (1) YU41472B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2826952A1 (de) * 1978-06-20 1980-01-10 Bayer Ag Enantiomerentrennung von chiralen carbonsaeuren
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid
JPS57145830A (en) * 1981-03-06 1982-09-09 Hiroyuki Nohira Optical resolution of 2-(4-chlorophenyl)-3-methylbutanoic acid
JPH01126425U (da) * 1988-02-23 1989-08-29
DE3824353A1 (de) * 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
DE4319438C1 (de) * 1993-06-11 1994-06-01 Gerd Dr Dr Geislinger Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
JP3782834B2 (ja) 1994-10-26 2006-06-07 株式会社トクホン 鎮痛抗炎症貼付剤
DE19717429A1 (de) * 1997-04-25 1998-12-24 Bayer Ag Herstellung enantiomerenreiner Biarylketocarbonsäuren
WO2010089343A1 (en) 2009-02-06 2010-08-12 Dsm Ip Assets B.V. Method for the synthesis of chiral alpha-aryl propionic acid derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23268A (en) * 1964-05-07 1969-02-27 Merck & Co Inc Anti-inflammatory preparations containing the 4-phenyl-alpha-methyl acid acetic phenyl acid
FR2015728A1 (en) * 1968-04-18 1970-04-30 Lilly Co Eli Anti-inflammatory substd-phenylalkanoic acids and - derivs
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids

Also Published As

Publication number Publication date
IE780467L (en) 1978-09-08
FR2383155A1 (fr) 1978-10-06
FI66828C (fi) 1984-12-10
DD136261A5 (de) 1979-06-27
DE2809794A1 (de) 1978-09-21
ATA163478A (de) 1980-06-15
DK154418B (da) 1988-11-14
EG13345A (en) 1981-06-30
NL189126C (nl) 1993-01-18
CS222255B2 (en) 1983-06-24
PL110888B1 (en) 1980-08-30
AU3397778A (en) 1979-09-13
PL205161A1 (pl) 1979-03-26
SU784759A3 (ru) 1980-11-30
DK154418C (da) 1989-06-19
GR64816B (en) 1980-06-03
DK100878A (da) 1978-09-09
IT1202818B (it) 1989-02-09
FR2383155B1 (da) 1983-12-30
LU79186A1 (fr) 1978-09-18
PT67743A (en) 1978-04-01
HU178810B (en) 1982-06-28
NO780785L (no) 1978-09-11
JPS53112841A (en) 1978-10-02
NL7802520A (nl) 1978-09-12
AU521708B2 (en) 1982-04-29
NL189126B (nl) 1992-08-17
JPS626536B2 (da) 1987-02-12
CA1105942A (en) 1981-07-28
DE2809794C2 (da) 1989-08-03
AT360508B (de) 1981-01-12
FI66828B (fi) 1984-08-31
YU41472B (en) 1987-08-31
IT7848320A0 (it) 1978-03-07
NO146197B (no) 1982-05-10
BG28567A3 (da) 1980-05-15
YU54078A (en) 1984-04-30
PH13333A (en) 1980-03-13
SE7802603L (sv) 1978-09-09
FI780738A (fi) 1978-09-09
SE436422B (sv) 1984-12-10
NO146197C (no) 1982-08-18
IN147834B (da) 1980-07-19
IE46476B1 (en) 1983-06-29
ES467606A1 (es) 1978-10-16
NZ186644A (en) 1980-10-24

Similar Documents

Publication Publication Date Title
US4209638A (en) Preparation of therapeutic agents
DE1668648C3 (de) 3-Benzoylphenylessigsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
CH638482A5 (en) Process for enlarging an enantiomeric portion of the acid constituent of a salt of a 2-arylpropionic acid
DE2723383C2 (da)
DE2310773A1 (de) Neue chinolinessigsaeurederivate und verfahren zu ihrer herstellung
DE2251097B2 (de) Verfahren zur gewinnung eines gemisches von (+)-cis- und (+)-trans-chrysanthemummonocarbonsaeure
DE2437882B2 (de) Verfahren zur herstellung von estern des 3-phenoxybenzylalkohols
DE2613817A1 (de) Phenylpropionsaeuren, pyruvatverfahren zu ihrer herstellung und verwendung
DE1768847B1 (de) Verfahren zur Abtrennung von d-trans-Chrysanthemumcarbonsaeure
CH659464A5 (de) Verfahren zur herstellung von 1,8-dihydroxy-10-acyl-9-anthronen.
DE2355785A1 (de) Verfahren zur chemischen spaltung racemischer formen von alpha-aminocarbonsaeurederivaten und die auf diesem weg erhaltenen produkte
CH640513A5 (de) Optisch aktive phenylalkansaeure-m-phenoxybenzylester.
DD145747A5 (de) Herstellung von hydroxyessigsaeurederivaten
DE3624912A1 (de) Optisch reine 1,3-dioxenone, verfahren zu ihrer herstellung und ihre verwendung
DE2362687C3 (de) Verfahren zur Gewinnung der optischen Isomeren des Penicillamins
DE2126597A1 (de) Aminothiophencarbonsäureester und Verfahren zu ihrer Herstellung
AT390613B (de) Verfahren zur herstellung des neuen rechtsdrehenden, optischen isomeren des diastereomeren a von ym-09730
DE664789C (de) Verfahren zur Herstellung von 4-Methyl-5-ª‰-oxyaethylthiazolen
DE2258088A1 (de) Optisch aktive isoindolinderivate und verfahren zu ihrer herstellung
DE946986C (de) Verfahren zur Herstellung von ª‡-Acetotetronsaeuren
DE3621835A1 (de) Verfahren zur racemisierung optisch aktiver (alpha)-phenoxypropionsaeure und deren derivate
CH628015A5 (de) Verfahren zur decarbalkoxylierung von carbonsaeureestern.
CH675419A5 (da)
DE69917163T2 (de) Verfahren zur herstellung von l-valinbenzylester-p-toluolsufonaten
GB1596032A (en) Resolution of optically active 2-arylpropionic acids

Legal Events

Date Code Title Description
PL Patent ceased