CA1105942A - Preparation of therapeutic agents - Google Patents
Preparation of therapeutic agentsInfo
- Publication number
- CA1105942A CA1105942A CA298,426A CA298426A CA1105942A CA 1105942 A CA1105942 A CA 1105942A CA 298426 A CA298426 A CA 298426A CA 1105942 A CA1105942 A CA 1105942A
- Authority
- CA
- Canada
- Prior art keywords
- process according
- acid
- salt
- alpha
- ethylamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9697/77A GB1596032A (en) | 1977-03-08 | 1977-03-08 | Resolution of optically active 2-arylpropionic acids |
| GB9697/77 | 1977-03-08 | ||
| GB1946/78 | 1978-01-18 | ||
| GB194678 | 1978-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1105942A true CA1105942A (en) | 1981-07-28 |
Family
ID=26237091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA298,426A Expired CA1105942A (en) | 1977-03-08 | 1978-03-07 | Preparation of therapeutic agents |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS53112841A (da) |
| AT (1) | AT360508B (da) |
| AU (1) | AU521708B2 (da) |
| BG (1) | BG28567A3 (da) |
| CA (1) | CA1105942A (da) |
| CH (1) | CH638482A5 (da) |
| CS (1) | CS222255B2 (da) |
| DD (1) | DD136261A5 (da) |
| DE (1) | DE2809794A1 (da) |
| DK (1) | DK154418C (da) |
| EG (1) | EG13345A (da) |
| ES (1) | ES467606A1 (da) |
| FI (1) | FI66828C (da) |
| FR (1) | FR2383155A1 (da) |
| GR (1) | GR64816B (da) |
| HU (1) | HU178810B (da) |
| IE (1) | IE46476B1 (da) |
| IN (1) | IN147834B (da) |
| IT (1) | IT1202818B (da) |
| LU (1) | LU79186A1 (da) |
| NL (1) | NL189126C (da) |
| NO (1) | NO146197C (da) |
| NZ (1) | NZ186644A (da) |
| PH (1) | PH13333A (da) |
| PL (1) | PL110888B1 (da) |
| PT (1) | PT67743A (da) |
| SE (1) | SE436422B (da) |
| SU (1) | SU784759A3 (da) |
| YU (1) | YU41472B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2826952A1 (de) * | 1978-06-20 | 1980-01-10 | Bayer Ag | Enantiomerentrennung von chiralen carbonsaeuren |
| PH15674A (en) * | 1979-07-06 | 1983-03-11 | Syntex Corp | Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid |
| JPS57145830A (en) * | 1981-03-06 | 1982-09-09 | Hiroyuki Nohira | Optical resolution of 2-(4-chlorophenyl)-3-methylbutanoic acid |
| JPH01126425U (da) * | 1988-02-23 | 1989-08-29 | ||
| DE3824353A1 (de) * | 1988-07-19 | 1990-01-25 | Paz Arzneimittelentwicklung | Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren |
| DE4028906A1 (de) * | 1990-09-12 | 1992-03-19 | Paz Arzneimittelentwicklung | Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen |
| DE4319438C1 (de) * | 1993-06-11 | 1994-06-01 | Gerd Dr Dr Geislinger | Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren |
| JP3782834B2 (ja) | 1994-10-26 | 2006-06-07 | 株式会社トクホン | 鎮痛抗炎症貼付剤 |
| DE19717429A1 (de) * | 1997-04-25 | 1998-12-24 | Bayer Ag | Herstellung enantiomerenreiner Biarylketocarbonsäuren |
| EP2393771A1 (en) | 2009-02-06 | 2011-12-14 | DSM IP Assets B.V. | Method for the synthesis of chiral alpha-aryl propionic acid derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL23268A (en) * | 1964-05-07 | 1969-02-27 | Merck & Co Inc | Anti-inflammatory preparations containing the 4-phenyl-alpha-methyl acid acetic phenyl acid |
| FR2015728A1 (en) * | 1968-04-18 | 1970-04-30 | Lilly Co Eli | Anti-inflammatory substd-phenylalkanoic acids and - derivs |
| US3686183A (en) * | 1969-03-24 | 1972-08-22 | Syntex Corp | Preparation of optical isomers of arylalkylacetic acids |
-
1978
- 1978-03-06 CS CS781413A patent/CS222255B2/cs unknown
- 1978-03-06 PT PT67743A patent/PT67743A/pt unknown
- 1978-03-06 GR GR55617A patent/GR64816B/el unknown
- 1978-03-07 HU HU78BO1703A patent/HU178810B/hu unknown
- 1978-03-07 SE SE7802603A patent/SE436422B/sv not_active IP Right Cessation
- 1978-03-07 DK DK100878A patent/DK154418C/da not_active IP Right Cessation
- 1978-03-07 YU YU540/78A patent/YU41472B/xx unknown
- 1978-03-07 NO NO780785A patent/NO146197C/no unknown
- 1978-03-07 ES ES467606A patent/ES467606A1/es not_active Expired
- 1978-03-07 AT AT163478A patent/AT360508B/de not_active IP Right Cessation
- 1978-03-07 SU SU782588501A patent/SU784759A3/ru active
- 1978-03-07 FI FI780738A patent/FI66828C/fi not_active IP Right Cessation
- 1978-03-07 CH CH249378A patent/CH638482A5/de not_active IP Right Cessation
- 1978-03-07 DE DE19782809794 patent/DE2809794A1/de active Granted
- 1978-03-07 CA CA298,426A patent/CA1105942A/en not_active Expired
- 1978-03-07 IT IT48320/78A patent/IT1202818B/it active
- 1978-03-07 IN IN241/CAL/78A patent/IN147834B/en unknown
- 1978-03-07 IE IE467/81A patent/IE46476B1/en not_active IP Right Cessation
- 1978-03-07 BG BG7838943A patent/BG28567A3/xx unknown
- 1978-03-08 JP JP2644878A patent/JPS53112841A/ja active Granted
- 1978-03-08 NZ NZ186644A patent/NZ186644A/xx unknown
- 1978-03-08 AU AU33977/78A patent/AU521708B2/en not_active Expired
- 1978-03-08 PL PL1978205161A patent/PL110888B1/pl unknown
- 1978-03-08 NL NLAANVRAGE7802520,A patent/NL189126C/xx not_active IP Right Cessation
- 1978-03-08 DD DD78204036A patent/DD136261A5/xx unknown
- 1978-03-08 LU LU79186A patent/LU79186A1/xx unknown
- 1978-03-08 FR FR7806692A patent/FR2383155A1/fr active Granted
- 1978-03-11 EG EG161/78A patent/EG13345A/xx active
- 1978-03-13 PH PH20873A patent/PH13333A/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |