CH638226A5 - Derivatives of 9-fluoroprednisolone - Google Patents

Derivatives of 9-fluoroprednisolone Download PDF

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Publication number
CH638226A5
CH638226A5 CH296278A CH296278A CH638226A5 CH 638226 A5 CH638226 A5 CH 638226A5 CH 296278 A CH296278 A CH 296278A CH 296278 A CH296278 A CH 296278A CH 638226 A5 CH638226 A5 CH 638226A5
Authority
CH
Switzerland
Prior art keywords
dione
hydroxy
pregnadiene
fluoro
compound according
Prior art date
Application number
CH296278A
Other languages
German (de)
English (en)
Inventor
Klaus Annen
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Joachim-Friedrich Kapp
Hans Wendt
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2712862A external-priority patent/DE2712862C2/de
Priority claimed from DE19782809732 external-priority patent/DE2809732C2/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of CH638226A5 publication Critical patent/CH638226A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH296278A 1977-03-21 1978-03-17 Derivatives of 9-fluoroprednisolone CH638226A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2712862A DE2712862C2 (de) 1977-03-21 1977-03-21 Derivate des 9-Fluorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE19782809732 DE2809732C2 (de) 1978-03-03 1978-03-03 Derivate des 9-Fluorprednisolons, Verfahren zu ihrer Herstellung, und pharmazeutische Präparate, die diese Wirkstoffe enthalten

Publications (1)

Publication Number Publication Date
CH638226A5 true CH638226A5 (en) 1983-09-15

Family

ID=25771793

Family Applications (1)

Application Number Title Priority Date Filing Date
CH296278A CH638226A5 (en) 1977-03-21 1978-03-17 Derivatives of 9-fluoroprednisolone

Country Status (20)

Country Link
JP (1) JPS53130651A (nl)
AT (1) AT365203B (nl)
AU (1) AU525614B2 (nl)
CA (1) CA1104124A (nl)
CH (1) CH638226A5 (nl)
CS (1) CS202591B2 (nl)
DD (1) DD134955A5 (nl)
DK (1) DK126378A (nl)
ES (1) ES468107A1 (nl)
FR (1) FR2384792A1 (nl)
GB (1) GB1603281A (nl)
GR (1) GR70385B (nl)
IE (1) IE46584B1 (nl)
IL (1) IL54308A (nl)
IT (1) IT1095477B (nl)
LU (1) LU79271A1 (nl)
NO (1) NO151043C (nl)
NZ (1) NZ186735A (nl)
RO (1) RO81525B (nl)
SE (1) SE431656B (nl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH07116215B2 (ja) * 1989-04-19 1995-12-13 エスエス製薬株式会社 新規なステロイド化合物
JPH07213320A (ja) * 1994-02-04 1995-08-15 Daiwa:Kk 長尺物用バック

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride
CH529739A (fr) * 1972-02-28 1972-10-31 Sdc Steroidi Dev Co Procédé pour la préparation d'un stéroïde de la série des prégnadiènes
US3832366A (en) * 1973-07-30 1974-08-27 Squibb & Sons Inc Process for preparing 21-chloro-17-acyloxy-20-ketosteroids

Also Published As

Publication number Publication date
IE780545L (en) 1978-09-21
NO151043B (no) 1984-10-22
IL54308A0 (en) 1978-06-15
JPS6131116B2 (nl) 1986-07-17
LU79271A1 (de) 1978-06-29
NZ186735A (en) 1980-10-24
NO780984L (no) 1978-09-22
SE431656B (sv) 1984-02-20
GB1603281A (en) 1981-11-25
ATA195978A (de) 1981-05-15
DD134955A5 (de) 1979-04-04
DK126378A (da) 1978-09-22
IL54308A (en) 1984-03-30
SE7803168L (sv) 1978-09-22
IE46584B1 (en) 1983-07-27
ES468107A1 (es) 1979-07-01
AU3434678A (en) 1979-09-27
CA1104124A (en) 1981-06-30
AU525614B2 (en) 1982-11-18
RO81525B (ro) 1983-04-30
FR2384792A1 (fr) 1978-10-20
IT7821364A0 (it) 1978-03-20
JPS53130651A (en) 1978-11-14
NO151043C (no) 1985-01-30
AT365203B (de) 1981-12-28
GR70385B (nl) 1982-10-05
RO81525A (ro) 1983-04-29
CS202591B2 (en) 1981-01-30
FR2384792B1 (nl) 1980-04-04
IT1095477B (it) 1985-08-10

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PL Patent ceased