DD134955A5 - Verfahren zur herstellung neuer derivate des 9-fluorprednisolons - Google Patents

Verfahren zur herstellung neuer derivate des 9-fluorprednisolons

Info

Publication number
DD134955A5
DD134955A5 DD78204259A DD20425978A DD134955A5 DD 134955 A5 DD134955 A5 DD 134955A5 DD 78204259 A DD78204259 A DD 78204259A DD 20425978 A DD20425978 A DD 20425978A DD 134955 A5 DD134955 A5 DD 134955A5
Authority
DD
German Democratic Republic
Prior art keywords
prednisolon
fluoro
producing new
new derivatives
derivatives
Prior art date
Application number
DD78204259A
Other languages
English (en)
Inventor
Klaus Annen
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Hans Wendt
Joachim-Friedrich Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2712862A external-priority patent/DE2712862C2/de
Priority claimed from DE19782809732 external-priority patent/DE2809732C2/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DD134955A5 publication Critical patent/DD134955A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD78204259A 1977-03-21 1978-03-17 Verfahren zur herstellung neuer derivate des 9-fluorprednisolons DD134955A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2712862A DE2712862C2 (de) 1977-03-21 1977-03-21 Derivate des 9-Fluorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE19782809732 DE2809732C2 (de) 1978-03-03 1978-03-03 Derivate des 9-Fluorprednisolons, Verfahren zu ihrer Herstellung, und pharmazeutische Präparate, die diese Wirkstoffe enthalten

Publications (1)

Publication Number Publication Date
DD134955A5 true DD134955A5 (de) 1979-04-04

Family

ID=25771793

Family Applications (1)

Application Number Title Priority Date Filing Date
DD78204259A DD134955A5 (de) 1977-03-21 1978-03-17 Verfahren zur herstellung neuer derivate des 9-fluorprednisolons

Country Status (20)

Country Link
JP (1) JPS53130651A (de)
AT (1) AT365203B (de)
AU (1) AU525614B2 (de)
CA (1) CA1104124A (de)
CH (1) CH638226A5 (de)
CS (1) CS202591B2 (de)
DD (1) DD134955A5 (de)
DK (1) DK126378A (de)
ES (1) ES468107A1 (de)
FR (1) FR2384792A1 (de)
GB (1) GB1603281A (de)
GR (1) GR70385B (de)
IE (1) IE46584B1 (de)
IL (1) IL54308A (de)
IT (1) IT1095477B (de)
LU (1) LU79271A1 (de)
NO (1) NO151043C (de)
NZ (1) NZ186735A (de)
RO (1) RO81525B (de)
SE (1) SE431656B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH07116215B2 (ja) * 1989-04-19 1995-12-13 エスエス製薬株式会社 新規なステロイド化合物
JPH07213320A (ja) * 1994-02-04 1995-08-15 Daiwa:Kk 長尺物用バック

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride
CH529739A (fr) * 1972-02-28 1972-10-31 Sdc Steroidi Dev Co Procédé pour la préparation d'un stéroïde de la série des prégnadiènes
US3832366A (en) * 1973-07-30 1974-08-27 Squibb & Sons Inc Process for preparing 21-chloro-17-acyloxy-20-ketosteroids

Also Published As

Publication number Publication date
NO780984L (no) 1978-09-22
RO81525A (ro) 1983-04-29
AU525614B2 (en) 1982-11-18
JPS6131116B2 (de) 1986-07-17
IE780545L (en) 1978-09-21
RO81525B (ro) 1983-04-30
IT1095477B (it) 1985-08-10
AT365203B (de) 1981-12-28
JPS53130651A (en) 1978-11-14
NO151043B (no) 1984-10-22
CS202591B2 (en) 1981-01-30
FR2384792B1 (de) 1980-04-04
AU3434678A (en) 1979-09-27
IT7821364A0 (it) 1978-03-20
DK126378A (da) 1978-09-22
IE46584B1 (en) 1983-07-27
LU79271A1 (de) 1978-06-29
ES468107A1 (es) 1979-07-01
SE7803168L (sv) 1978-09-22
GR70385B (de) 1982-10-05
IL54308A0 (en) 1978-06-15
IL54308A (en) 1984-03-30
CH638226A5 (en) 1983-09-15
FR2384792A1 (fr) 1978-10-20
NO151043C (no) 1985-01-30
SE431656B (sv) 1984-02-20
ATA195978A (de) 1981-05-15
GB1603281A (en) 1981-11-25
NZ186735A (en) 1980-10-24
CA1104124A (en) 1981-06-30

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