CH636012A5 - Pharmacologically acceptable bile acid sequestering agent composition and process for its preparation - Google Patents

Pharmacologically acceptable bile acid sequestering agent composition and process for its preparation Download PDF

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Publication number
CH636012A5
CH636012A5 CH162578A CH162578A CH636012A5 CH 636012 A5 CH636012 A5 CH 636012A5 CH 162578 A CH162578 A CH 162578A CH 162578 A CH162578 A CH 162578A CH 636012 A5 CH636012 A5 CH 636012A5
Authority
CH
Switzerland
Prior art keywords
poly
iminio
methyl
dichloride
water
Prior art date
Application number
CH162578A
Other languages
German (de)
English (en)
Inventor
Arthur Franklin Wagner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH636012A5 publication Critical patent/CH636012A5/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CH162578A 1977-02-17 1978-02-14 Pharmacologically acceptable bile acid sequestering agent composition and process for its preparation CH636012A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76949177A 1977-02-17 1977-02-17

Publications (1)

Publication Number Publication Date
CH636012A5 true CH636012A5 (en) 1983-05-13

Family

ID=25085598

Family Applications (1)

Application Number Title Priority Date Filing Date
CH162578A CH636012A5 (en) 1977-02-17 1978-02-14 Pharmacologically acceptable bile acid sequestering agent composition and process for its preparation

Country Status (26)

Country Link
JP (1) JPS53102958A (sv)
AT (1) AT363173B (sv)
AU (1) AU518127B2 (sv)
BE (1) BE863930A (sv)
CA (1) CA1109395A (sv)
CH (1) CH636012A5 (sv)
DE (1) DE2806707A1 (sv)
DK (1) DK46578A (sv)
ES (1) ES466892A1 (sv)
FI (1) FI67483C (sv)
FR (1) FR2381079A1 (sv)
GB (1) GB1567294A (sv)
GR (1) GR66100B (sv)
HU (1) HU177685B (sv)
IE (1) IE46408B1 (sv)
IL (1) IL53978A (sv)
IT (1) IT7848013A0 (sv)
LU (1) LU79071A1 (sv)
NL (1) NL7801240A (sv)
NO (1) NO148838C (sv)
NZ (1) NZ186399A (sv)
PH (1) PH15263A (sv)
PL (1) PL122299B1 (sv)
PT (1) PT67663B (sv)
SE (1) SE433170B (sv)
ZA (1) ZA78913B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US5709880A (en) * 1995-07-10 1998-01-20 Buckman Laboratories International, Inc. Method of making tabletized ionene polymers
EP0778027A3 (de) 1995-12-04 1998-04-01 Helmut Univ.-Prof. Dr. Wachter Verwendung von Kieselerde zur Herstellung von Arzneimitteln
JP4010585B2 (ja) * 1996-10-15 2007-11-21 久光製薬株式会社 陰イオン交換樹脂を含有する錠剤
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206115A1 (es) * 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado
US4027009A (en) * 1973-06-11 1977-05-31 Merck & Co., Inc. Compositions and methods for depressing blood serum cholesterol

Also Published As

Publication number Publication date
AU518127B2 (en) 1981-09-17
CA1109395A (en) 1981-09-22
IE46408B1 (en) 1983-06-01
IT7848013A0 (it) 1978-02-10
FI780296A (fi) 1978-08-18
NO780367L (no) 1978-08-18
ATA87978A (de) 1980-12-15
ZA78913B (en) 1979-09-26
ES466892A1 (es) 1979-08-16
HU177685B (en) 1981-12-28
IE780332L (en) 1978-08-17
IL53978A0 (en) 1978-04-30
PL204642A1 (pl) 1979-06-04
FR2381079A1 (fr) 1978-09-15
SE7801242L (sv) 1978-08-18
AT363173B (de) 1981-07-10
GB1567294A (en) 1980-05-14
PT67663A (en) 1978-03-01
NL7801240A (nl) 1978-08-21
SE433170B (sv) 1984-05-14
DK46578A (da) 1978-08-18
FI67483B (fi) 1984-12-31
GR66100B (sv) 1981-01-16
PT67663B (en) 1980-03-03
BE863930A (fr) 1978-08-14
FR2381079B1 (sv) 1981-09-11
IL53978A (en) 1981-03-31
FI67483C (fi) 1985-04-10
NZ186399A (en) 1980-11-28
PL122299B1 (en) 1982-07-31
PH15263A (en) 1982-11-02
NO148838B (no) 1983-09-19
NO148838C (no) 1983-12-28
LU79071A1 (fr) 1978-09-28
JPS53102958A (en) 1978-09-07
AU3309978A (en) 1979-08-16
DE2806707A1 (de) 1978-08-24

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