CH628907A5 - Process for the preparation of 24,25-dihydroxycholesterol derivatives - Google Patents
Process for the preparation of 24,25-dihydroxycholesterol derivatives Download PDFInfo
- Publication number
- CH628907A5 CH628907A5 CH1224676A CH1224676A CH628907A5 CH 628907 A5 CH628907 A5 CH 628907A5 CH 1224676 A CH1224676 A CH 1224676A CH 1224676 A CH1224676 A CH 1224676A CH 628907 A5 CH628907 A5 CH 628907A5
- Authority
- CH
- Switzerland
- Prior art keywords
- hydroxy
- methoxy
- mixture
- cyclo
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/621,319 US3994878A (en) | 1975-10-10 | 1975-10-10 | Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof |
US05/623,859 US4038272A (en) | 1975-10-20 | 1975-10-20 | Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CH628907A5 true CH628907A5 (en) | 1982-03-31 |
Family
ID=27088923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1224676A CH628907A5 (en) | 1975-10-10 | 1976-09-28 | Process for the preparation of 24,25-dihydroxycholesterol derivatives |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5246061A (ja) |
AT (1) | AT355236B (ja) |
CH (1) | CH628907A5 (ja) |
DE (1) | DE2645527A1 (ja) |
FR (2) | FR2407941A1 (ja) |
GB (5) | GB1564806A (ja) |
IT (1) | IT1068692B (ja) |
NL (1) | NL7611155A (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH644873A5 (de) * | 1980-02-12 | 1984-08-31 | Hoffmann La Roche | Verfahren zur herstellung von cholesterinderivaten. |
SI3461834T1 (sl) | 2013-03-13 | 2021-11-30 | Sage Therapeutics, Inc. | Nevroaktivni steroidi |
US10696712B2 (en) * | 2015-07-06 | 2020-06-30 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
PE20180482A1 (es) | 2015-07-06 | 2018-03-07 | Sage Therapeutics Inc | Oxiesteroles y metodos de uso de los mismos |
AU2017240157B2 (en) | 2016-04-01 | 2022-10-20 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
US10752653B2 (en) | 2016-05-06 | 2020-08-25 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
DK3481846T3 (da) | 2016-07-07 | 2021-08-16 | Sage Therapeutics Inc | 11-substituerede 24-hydroxysteroler til anvendelse til behandling af nmda-relaterede tilstande |
JP7149266B2 (ja) | 2016-09-30 | 2022-10-06 | セージ セラピューティクス, インコーポレイテッド | C7置換オキシステロールおよびnmdaモジュレーターとしての方法 |
EP3529257B1 (en) | 2016-10-18 | 2023-05-10 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7402846A (ja) * | 1973-03-02 | 1974-09-04 | ||
US3822254A (en) * | 1973-05-21 | 1974-07-02 | Hoffmann La Roche | Synthesis of 25-hydroxycholesterol |
-
1976
- 1976-09-28 CH CH1224676A patent/CH628907A5/de not_active IP Right Cessation
- 1976-10-08 AT AT751376A patent/AT355236B/de not_active IP Right Cessation
- 1976-10-08 GB GB4193876A patent/GB1564806A/en not_active Expired
- 1976-10-08 GB GB2314277A patent/GB1564810A/en not_active Expired
- 1976-10-08 DE DE19762645527 patent/DE2645527A1/de not_active Ceased
- 1976-10-08 GB GB2314177A patent/GB1564809A/en not_active Expired
- 1976-10-08 NL NL7611155A patent/NL7611155A/xx not_active Application Discontinuation
- 1976-10-08 GB GB2313977A patent/GB1564807A/en not_active Expired
- 1976-10-08 JP JP12050076A patent/JPS5246061A/ja active Pending
- 1976-10-08 IT IT2816476A patent/IT1068692B/it active
- 1976-10-08 GB GB2314077A patent/GB1564808A/en not_active Expired
- 1976-10-11 FR FR7630450A patent/FR2407941A1/fr active Granted
-
1977
- 1977-04-22 FR FR7712223A patent/FR2351998A1/fr active Granted
Also Published As
Publication number | Publication date |
---|---|
GB1564807A (en) | 1980-04-16 |
IT1068692B (it) | 1985-03-21 |
JPS5246061A (en) | 1977-04-12 |
FR2351998A1 (fr) | 1977-12-16 |
FR2351998B1 (ja) | 1980-04-25 |
GB1564808A (en) | 1980-04-16 |
NL7611155A (nl) | 1977-04-13 |
GB1564810A (en) | 1980-04-16 |
AT355236B (de) | 1980-02-25 |
GB1564809A (en) | 1980-04-16 |
GB1564806A (en) | 1980-04-16 |
FR2407941A1 (fr) | 1979-06-01 |
DE2645527A1 (de) | 1977-04-21 |
FR2407941B1 (ja) | 1980-05-16 |
ATA751376A (de) | 1979-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |