JPS5246061A - Novel cholesterol derivatives - Google Patents

Novel cholesterol derivatives

Info

Publication number
JPS5246061A
JPS5246061A JP12050076A JP12050076A JPS5246061A JP S5246061 A JPS5246061 A JP S5246061A JP 12050076 A JP12050076 A JP 12050076A JP 12050076 A JP12050076 A JP 12050076A JP S5246061 A JPS5246061 A JP S5246061A
Authority
JP
Japan
Prior art keywords
cholesterol derivatives
novel cholesterol
novel
derivatives
cholesterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12050076A
Other languages
Japanese (ja)
Inventor
Jiyosefu Paatoritsuji Jiyon
Radojie Usukokobitsuku Miran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/621,319 external-priority patent/US3994878A/en
Priority claimed from US05/623,859 external-priority patent/US4038272A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5246061A publication Critical patent/JPS5246061A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
JP12050076A 1975-10-10 1976-10-08 Novel cholesterol derivatives Pending JPS5246061A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/621,319 US3994878A (en) 1975-10-10 1975-10-10 Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof
US05/623,859 US4038272A (en) 1975-10-20 1975-10-20 Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof

Publications (1)

Publication Number Publication Date
JPS5246061A true JPS5246061A (en) 1977-04-12

Family

ID=27088923

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12050076A Pending JPS5246061A (en) 1975-10-10 1976-10-08 Novel cholesterol derivatives

Country Status (8)

Country Link
JP (1) JPS5246061A (en)
AT (1) AT355236B (en)
CH (1) CH628907A5 (en)
DE (1) DE2645527A1 (en)
FR (2) FR2407941A1 (en)
GB (5) GB1564807A (en)
IT (1) IT1068692B (en)
NL (1) NL7611155A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018519329A (en) * 2015-07-06 2018-07-19 セージ セラピューティクス， インコーポレイテッド Oxysterols and methods of their use

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH644873A5 (en) * 1980-02-12 1984-08-31 Hoffmann La Roche METHOD FOR PRODUCING CHOLESTEROL DERIVATIVES.
DK3461834T3 (en) 2013-03-13 2021-08-23 Sage Therapeutics Inc NEUROACTIVE STEROIDS
MD3319612T2 (en) 2015-07-06 2021-10-31 Sage Therapeutics Inc Oxysterols and methods of use thereof
JP7112331B2 (en) 2016-04-01 2022-08-03 セージ セラピューティクス， インコーポレイテッド Oxysterols and their uses
US10752653B2 (en) 2016-05-06 2020-08-25 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
PL3481846T3 (en) 2016-07-07 2021-12-20 Sage Therapeutics, Inc. 11-substituted 24-hydroxysterols for use in the treatment of nmda related conditions
PT3519422T (en) 2016-09-30 2022-12-05 Sage Therapeutics Inc C7 substituted oxysterols and methods as nmda modulators
IL266093B2 (en) 2016-10-18 2024-02-01 Sage Therapeutics Inc Oxysterols and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2219943B1 (en) * 1973-03-02 1976-04-30 Eisai Co Ltd
US3822254A (en) * 1973-05-21 1974-07-02 Hoffmann La Roche Synthesis of 25-hydroxycholesterol

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018519329A (en) * 2015-07-06 2018-07-19 セージ セラピューティクス， インコーポレイテッド Oxysterols and methods of their use
JP2021063118A (en) * 2015-07-06 2021-04-22 セージ セラピューティクス， インコーポレイテッド Oxysterols and methods of use thereof

Also Published As

Publication number Publication date
GB1564807A (en) 1980-04-16
FR2351998B1 (en) 1980-04-25
CH628907A5 (en) 1982-03-31
ATA751376A (en) 1979-07-15
IT1068692B (en) 1985-03-21
FR2407941A1 (en) 1979-06-01
FR2407941B1 (en) 1980-05-16
FR2351998A1 (en) 1977-12-16
GB1564808A (en) 1980-04-16
DE2645527A1 (en) 1977-04-21
GB1564809A (en) 1980-04-16
AT355236B (en) 1980-02-25
NL7611155A (en) 1977-04-13
GB1564810A (en) 1980-04-16
GB1564806A (en) 1980-04-16

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