AT355236B - Verfahren zur herstellung von 24,25-dihydroxy- cholesterinderivaten - Google Patents

Verfahren zur herstellung von 24,25-dihydroxy- cholesterinderivaten

Info

Publication number
AT355236B
AT355236B AT751376A AT751376A AT355236B AT 355236 B AT355236 B AT 355236B AT 751376 A AT751376 A AT 751376A AT 751376 A AT751376 A AT 751376A AT 355236 B AT355236 B AT 355236B
Authority
AT
Austria
Prior art keywords
dihydroxy
producing
cholesterin
derivatives
cholesterin derivatives
Prior art date
Application number
AT751376A
Other languages
German (de)
English (en)
Other versions
ATA751376A (de
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/621,319 external-priority patent/US3994878A/en
Priority claimed from US05/623,859 external-priority patent/US4038272A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA751376A publication Critical patent/ATA751376A/de
Priority to AT0546379A priority Critical patent/AT364099B/de
Priority to AT546479A priority patent/AT361642B/de
Priority to AT0546579A priority patent/AT364100B/de
Application granted granted Critical
Publication of AT355236B publication Critical patent/AT355236B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT751376A 1975-10-10 1976-10-08 Verfahren zur herstellung von 24,25-dihydroxy- cholesterinderivaten AT355236B (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AT0546379A AT364099B (de) 1975-10-10 1979-08-10 Verfahren zur herstellung von neuen cholesterinderivaten
AT546479A AT361642B (de) 1975-10-10 1979-08-10 Verfahren zur herstellung von neuen cholesterinderivaten
AT0546579A AT364100B (de) 1975-10-10 1979-08-10 Verfahren zur herstellung von neuen cholesterinderivaten

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/621,319 US3994878A (en) 1975-10-10 1975-10-10 Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof
US05/623,859 US4038272A (en) 1975-10-20 1975-10-20 Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof

Publications (2)

Publication Number Publication Date
ATA751376A ATA751376A (de) 1979-07-15
AT355236B true AT355236B (de) 1980-02-25

Family

ID=27088923

Family Applications (1)

Application Number Title Priority Date Filing Date
AT751376A AT355236B (de) 1975-10-10 1976-10-08 Verfahren zur herstellung von 24,25-dihydroxy- cholesterinderivaten

Country Status (8)

Country Link
JP (1) JPS5246061A (ja)
AT (1) AT355236B (ja)
CH (1) CH628907A5 (ja)
DE (1) DE2645527A1 (ja)
FR (2) FR2407941A1 (ja)
GB (5) GB1564810A (ja)
IT (1) IT1068692B (ja)
NL (1) NL7611155A (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH644873A5 (de) * 1980-02-12 1984-08-31 Hoffmann La Roche Verfahren zur herstellung von cholesterinderivaten.
WO2014160480A1 (en) 2013-03-13 2014-10-02 Sage Therapeutics, Inc. Neuroactive steroids and methods of use thereof
US11117924B2 (en) 2015-07-06 2021-09-14 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
EP4316591A3 (en) * 2015-07-06 2024-04-24 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
BR112018070123A2 (pt) 2016-04-01 2019-02-05 Sage Therapeutics Inc oxiesterós e métodos de uso dos mesmos
WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
CA3029900A1 (en) 2016-07-07 2018-01-11 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
EP3519422B1 (en) 2016-09-30 2022-08-31 Sage Therapeutics, Inc. C7 substituted oxysterols and these compounds for use as nmda modulators
CN115181153A (zh) 2016-10-18 2022-10-14 萨奇治疗股份有限公司 氧甾醇及其使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2219943B1 (ja) * 1973-03-02 1976-04-30 Eisai Co Ltd
US3822254A (en) * 1973-05-21 1974-07-02 Hoffmann La Roche Synthesis of 25-hydroxycholesterol

Also Published As

Publication number Publication date
GB1564807A (en) 1980-04-16
GB1564810A (en) 1980-04-16
FR2407941A1 (fr) 1979-06-01
ATA751376A (de) 1979-07-15
FR2351998B1 (ja) 1980-04-25
IT1068692B (it) 1985-03-21
NL7611155A (nl) 1977-04-13
JPS5246061A (en) 1977-04-12
DE2645527A1 (de) 1977-04-21
GB1564808A (en) 1980-04-16
FR2351998A1 (fr) 1977-12-16
GB1564809A (en) 1980-04-16
GB1564806A (en) 1980-04-16
FR2407941B1 (ja) 1980-05-16
CH628907A5 (en) 1982-03-31

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee