CH627761A5 - Process for the preparation of 17 beta esters of testosterone and 5 alpha-dihydrotestosterone - Google Patents

Process for the preparation of 17 beta esters of testosterone and 5 alpha-dihydrotestosterone Download PDF

Info

Publication number
CH627761A5
CH627761A5 CH640477A CH640477A CH627761A5 CH 627761 A5 CH627761 A5 CH 627761A5 CH 640477 A CH640477 A CH 640477A CH 640477 A CH640477 A CH 640477A CH 627761 A5 CH627761 A5 CH 627761A5
Authority
CH
Switzerland
Prior art keywords
esters
acid
alkyl group
preparation
testosterone
Prior art date
Application number
CH640477A
Other languages
German (de)
English (en)
Inventor
Johannes Van Der Vies
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/691,103 external-priority patent/US4098802A/en
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of CH627761A5 publication Critical patent/CH627761A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0025—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH640477A 1976-05-28 1977-05-24 Process for the preparation of 17 beta esters of testosterone and 5 alpha-dihydrotestosterone CH627761A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/691,103 US4098802A (en) 1975-02-18 1976-05-28 Oral pharmaceutical preparation having androgenic activity

Publications (1)

Publication Number Publication Date
CH627761A5 true CH627761A5 (en) 1982-01-29

Family

ID=24775172

Family Applications (1)

Application Number Title Priority Date Filing Date
CH640477A CH627761A5 (en) 1976-05-28 1977-05-24 Process for the preparation of 17 beta esters of testosterone and 5 alpha-dihydrotestosterone

Country Status (12)

Country Link
JP (1) JPS52148060A (fr)
AR (1) AR214323A1 (fr)
BE (1) BE855163A (fr)
CH (1) CH627761A5 (fr)
DE (1) DE2723876C2 (fr)
DK (1) DK146096C (fr)
ES (1) ES459230A1 (fr)
FI (1) FI57597C (fr)
FR (1) FR2352832A1 (fr)
GB (1) GB1567515A (fr)
NL (1) NL7705790A (fr)
SE (1) SE425493B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL153648A0 (en) * 2000-08-23 2003-07-06 Akzo Nobel Nv Novel testosterone ester formulation for human use
JO2505B1 (en) 2003-03-14 2009-10-05 باير شيرنغ فارما اكتنجيسيلشافت Pharmacy methods and formulations for obtaining acceptable serum testosterone levels
GB0807605D0 (en) * 2008-04-28 2008-06-04 Diurnal Ltd Lipid composition
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
TW201521731A (zh) * 2013-03-15 2015-06-16 利波辛股份有限公司 用於口服之脂平衡的長鏈睪固酮酯
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189235C (nl) * 1974-02-28 1993-02-16 Akzo Nv Werkwijze voor de bereiding van een oraal toe te dienen farmaceutisch preparaat met androgene werking.

Also Published As

Publication number Publication date
JPS6145637B2 (fr) 1986-10-08
NL7705790A (nl) 1977-11-30
DE2723876C2 (de) 1986-10-30
DK236877A (da) 1977-11-29
SE7706235L (sv) 1977-11-29
FR2352832B1 (fr) 1980-07-11
ES459230A1 (es) 1978-11-16
FI57597B (fi) 1980-05-30
GB1567515A (en) 1980-05-14
FI771684A (fr) 1977-11-29
BE855163A (fr) 1977-11-28
FI57597C (fi) 1980-09-10
DK146096C (da) 1983-11-21
DE2723876A1 (de) 1977-12-15
JPS52148060A (en) 1977-12-08
AR214323A1 (es) 1979-05-31
FR2352832A1 (fr) 1977-12-23
DK146096B (da) 1983-06-27
SE425493B (sv) 1982-10-04

Similar Documents

Publication Publication Date Title
DE2624025C2 (fr)
DE69031033T2 (de) Verwendung von eicosapentaensäure zur behandlung der kachexie
US4083973A (en) Pharmaceutical preparation adapted for oral administration
DE2508615C2 (fr)
DE3438630A1 (de) Kombinierte fettsaeurezusammensetzung zur senkung des cholesterin- und triglycerid-blutspiegels
EP0241809A1 (fr) Association synergétique d'amantadine et de sélégiline
DE2752695A1 (de) Steroidester
DE2414680C2 (de) Substituierte 2-Furancarbonsäuren und 2-Furancarbonsäureester, Verfahren zu ihrer Herstellung und Arzneimittel, die diese Verbindungen enthalten
DE2549783C3 (de) Triglyceride mit entzündungshemmender Wirkung
CH641352A5 (de) 15-(hydroxy-, acyloxy- oder oxo-)steroide enthaltende mittel zur hemmung der biosynthese der mevalonsaeure.
LU84892A1 (fr) Komposition zur reduktion der sebumsekretion
DE2723876C2 (de) 17β-Ester von Testosteron
EP0369216B1 (fr) Préparation pharmaceutique de dérivés estériques de l'hécogénine et leur utilisation pour le traitement de l'hyperplasie prostatique bénigne
WO1999002177A1 (fr) Composition pharmaceutique contenant du peptichemio
DE2948733A1 (de) Steroidspirothiazolidinderivate, verfahren zur herstellung derselben und diese enhaltende arzneimittel
DE1801750A1 (de) Von Prostaglandinen abgeleitete Verbindungen und Verfahren zu ihrer Herstellung
DE2504045B2 (de) 16,17 dihydro-apovincaminsaeure-2- hydroxypropylester, deren salze, verfahren zu ihrer herstellung und arzneimittel
DE2252637A1 (de) Choleretische arzneimittel
DE69125204T2 (de) Therapeutische Anwendung von Histamin-H3-Agonisten, neue Wirkstoffe und Verwendung zur Herstellung von Arzneimitteln
DE2748291A1 (de) Triglyceride, verfahren zu ihrer herstellung und ihre verwendung zur behandlung von entzuendungen
CH652303A5 (de) Verwendung von polyprenylderivaten fuer die herstellung eines mittels fuer die aeusserliche behandlung von wunden oder von suppositorien fuer die behandlung von wunden bei menschen und tieren.
DE2055039C2 (de) Arzneimittel, enthaltend ein wasserlösliches Salz eines α-Tocopherol-Derivats
DE2515142B2 (de) Oral verabfolgbare mittel zur senkung des lipid- und cholesterin- spiegels
CH630645A5 (en) Process for preparing novel 17beta esters of oestradiol
DE3028255A1 (de) Neues halogen-derivat aus der 16 alpha -methylpregnan-reihe, seine herstellung, seine verwendung als arzneimittel und die es enthaltenden zusammensetzungen

Legal Events

Date Code Title Description
PL Patent ceased