CH624682A5 - - Google Patents

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Publication number
CH624682A5
CH624682A5 CH1415776A CH1415776A CH624682A5 CH 624682 A5 CH624682 A5 CH 624682A5 CH 1415776 A CH1415776 A CH 1415776A CH 1415776 A CH1415776 A CH 1415776A CH 624682 A5 CH624682 A5 CH 624682A5
Authority
CH
Switzerland
Prior art keywords
compounds
formula
administered
administration
group
Prior art date
Application number
CH1415776A
Other languages
German (de)
English (en)
Inventor
Fritz Dr Hunziker
Rudolf Fischer
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to CH1415776A priority Critical patent/CH624682A5/de
Priority to DK485677AA priority patent/DK140724B/da
Priority to FI773273A priority patent/FI64143C/fi
Priority to SE7712387A priority patent/SE435510B/xx
Priority to DE2748920A priority patent/DE2748920C2/de
Priority to GB16347/80A priority patent/GB1592330A/en
Priority to GB45932/77A priority patent/GB1592329A/en
Priority to NLAANVRAGE7712171,A priority patent/NL175297C/xx
Priority to CY1269A priority patent/CY1269A/xx
Priority to PH20407A priority patent/PH13515A/en
Priority to NZ185642A priority patent/NZ185642A/xx
Priority to ES463971A priority patent/ES463971A1/es
Priority to JP52133151A priority patent/JPS5929076B2/ja
Priority to AU30467/77A priority patent/AU517829B2/en
Priority to NZ191043A priority patent/NZ191043A/xx
Priority to FR7733524A priority patent/FR2370745A1/fr
Priority to CA290,464A priority patent/CA1086315A/en
Priority to PT67247A priority patent/PT67247B/pt
Priority to BE182454A priority patent/BE860613A/xx
Priority to IE2279/77A priority patent/IE46262B1/en
Priority to IL53332A priority patent/IL53332A/xx
Priority to IE654/82A priority patent/IE46263B1/en
Priority to AT0799177A priority patent/AT366682B/de
Priority to SU2539049A priority patent/SU686616A3/ru
Priority to CH774280A priority patent/CH630916A5/de
Priority to US06/111,459 priority patent/US4308207A/en
Publication of CH624682A5 publication Critical patent/CH624682A5/de
Priority to US06/304,357 priority patent/US4406900A/en
Priority to HK322/82A priority patent/HK32282A/xx
Priority to SG665/84A priority patent/SG66584G/en
Priority to KE3472A priority patent/KE3472A/xx
Priority to MY56/84A priority patent/MY8400056A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH1415776A 1976-11-10 1976-11-10 CH624682A5 (pt)

Priority Applications (31)

Application Number Priority Date Filing Date Title
CH1415776A CH624682A5 (pt) 1976-11-10 1976-11-10
DK485677AA DK140724B (da) 1976-11-10 1977-11-01 Analogifremgangsmåde til fremstilling af 3-fluor-6-(4-methyl-1-piperazinyl)morphanthridin.
FI773273A FI64143C (fi) 1976-11-10 1977-11-01 Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin
SE7712387A SE435510B (sv) 1976-11-10 1977-11-02 Analogiforfarande for framstellning av 3-fluor-6-piperazinylmorfantridiner
DE2748920A DE2748920C2 (de) 1976-11-10 1977-11-02 3-Fluor-6-piperazino-morphanthridine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
GB16347/80A GB1592330A (en) 1976-11-10 1977-11-04 Morphanthridine derivative
GB45932/77A GB1592329A (en) 1976-11-10 1977-11-04 Morphanthridines
NLAANVRAGE7712171,A NL175297C (nl) 1976-11-10 1977-11-04 Werkwijze voor het bereiden en/of vervaardigen van een farmaceutisch preparaat, dat een of een aantal op de 6-plaats gesubstitueerde morfanthridinederivaten en/of de zuuradditiezouten daarvan bevat, alsmede werkwijze voor het bereiden van dergelijke morfanthridinederivaten.
CY1269A CY1269A (en) 1976-11-10 1977-11-04 Morphanthridine derivative
FR7733524A FR2370745A1 (fr) 1976-11-10 1977-11-08 Nouveaux derives de la morphanthridine, leur preparation et leur application comme medicaments
IL53332A IL53332A (en) 1976-11-10 1977-11-08 3-fluoro-6-piperazino-morphanthridine derivatives,their production and pharmaceutical compositions containing them
ES463971A ES463971A1 (es) 1976-11-10 1977-11-08 Perfeccionamientos en o relacionados con compuestos organi- cos.
JP52133151A JPS5929076B2 (ja) 1976-11-10 1977-11-08 化合物
AU30467/77A AU517829B2 (en) 1976-11-10 1977-11-08 Morphanthridine derivatives
NZ191043A NZ191043A (en) 1976-11-10 1977-11-08 3-fluoro-6-(4-methyl-1-piperazinyl)-morphanthridine
PH20407A PH13515A (en) 1976-11-10 1977-11-08 Morphantridine derivative
CA290,464A CA1086315A (en) 1976-11-10 1977-11-08 Morphanthridine derivatives
PT67247A PT67247B (en) 1976-11-10 1977-11-08 Process for preparing organic compounds with pharmaceutical activity
BE182454A BE860613A (fr) 1976-11-10 1977-11-08 Nouveaux derives de la morphanthridine, leur preparation et leur application comme medicaments
IE2279/77A IE46262B1 (en) 1976-11-10 1977-11-08 Morphanthridines
NZ185642A NZ185642A (en) 1976-11-10 1977-11-08 Morphanthridine derivatives and pharmaceutical compositions
IE654/82A IE46263B1 (en) 1976-11-10 1977-11-08 A morphanthridine derivative
AT0799177A AT366682B (de) 1976-11-10 1977-11-09 Verfahren zur herstellung neuer 3-fluor-6piperazinylmorphanthridine und ihrer saeureadditionssalze
SU2539049A SU686616A3 (ru) 1976-11-10 1977-11-09 Способ получени производных 3-фтор-6-пиперазинил-морфантридина или их солей
CH774280A CH630916A5 (en) 1976-11-10 1978-01-01 3-Fluoromorphanthridines.
US06/111,459 US4308207A (en) 1976-11-10 1980-01-11 Morphanthridine derivatives
US06/304,357 US4406900A (en) 1976-11-10 1981-09-22 Neuroleptic use of morphanthridines
HK322/82A HK32282A (en) 1976-11-10 1982-07-15 A morphanthridine derivative
SG665/84A SG66584G (en) 1976-11-10 1984-09-20 A morphanthridine derivative
KE3472A KE3472A (en) 1976-11-10 1984-10-17 A morphanthridine derivative
MY56/84A MY8400056A (en) 1976-11-10 1984-12-30 A morphanthridine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1415776A CH624682A5 (pt) 1976-11-10 1976-11-10

Publications (1)

Publication Number Publication Date
CH624682A5 true CH624682A5 (pt) 1981-08-14

Family

ID=4398460

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1415776A CH624682A5 (pt) 1976-11-10 1976-11-10

Country Status (26)

Country Link
US (1) US4308207A (pt)
JP (1) JPS5929076B2 (pt)
AT (1) AT366682B (pt)
AU (1) AU517829B2 (pt)
BE (1) BE860613A (pt)
CA (1) CA1086315A (pt)
CH (1) CH624682A5 (pt)
CY (1) CY1269A (pt)
DE (1) DE2748920C2 (pt)
DK (1) DK140724B (pt)
ES (1) ES463971A1 (pt)
FI (1) FI64143C (pt)
FR (1) FR2370745A1 (pt)
GB (2) GB1592329A (pt)
HK (1) HK32282A (pt)
IE (1) IE46262B1 (pt)
IL (1) IL53332A (pt)
KE (1) KE3472A (pt)
MY (1) MY8400056A (pt)
NL (1) NL175297C (pt)
NZ (2) NZ191043A (pt)
PH (1) PH13515A (pt)
PT (1) PT67247B (pt)
SE (1) SE435510B (pt)
SG (1) SG66584G (pt)
SU (1) SU686616A3 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3402060A1 (de) * 1984-01-21 1985-08-01 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
JPH05506249A (ja) * 1990-10-10 1993-09-16 シェリング・コーポレーション ビスーベンゾシクロヘプタピペリジリデン、ピペリジンおよびピペラジン化合物、組成物および使用法
BR0314108A (pt) * 2002-09-18 2006-04-25 Fmc Corp derivados tricìclios inseticidas
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
JP2006515628A (ja) * 2003-01-23 2006-06-01 アカディア ファーマシューティカルズ，インコーポレーテッド ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
AU2004308955B2 (en) * 2003-12-22 2011-08-04 Acadia Pharmaceuticals Inc. Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
AU2005257768A1 (en) * 2004-04-01 2006-01-05 Acadia Pharmaceuticals Inc. Method of synthesis and isolation of solid N-desmethylclozapine and crystalline forms thereof
WO2007053618A1 (en) * 2005-10-31 2007-05-10 Acadia Pharmaceuticals Inc. Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL140242B (nl) * 1963-03-01 1973-11-15 Wander Ag Dr A Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen.
GB1006156A (en) * 1963-06-14 1965-09-29 Wander Ag Dr A 6-basic substituted morphanthridines
US3389139A (en) * 1963-06-14 1968-06-18 Wander Ag Dr A 6-homopiperazino and piperazinomorphanthridines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US3962248A (en) * 1972-04-04 1976-06-08 Sandoz, Inc. Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
CH601287A5 (pt) * 1975-08-06 1978-07-14 Sandoz Ag

Also Published As

Publication number Publication date
DK140724B (da) 1979-11-05
ES463971A1 (es) 1978-12-01
GB1592329A (en) 1981-07-08
GB1592330A (en) 1981-07-08
NL175297C (nl) 1984-10-16
SU686616A1 (en) 1979-09-15
CA1086315A (en) 1980-09-23
FR2370745A1 (fr) 1978-06-09
DE2748920A1 (de) 1978-05-11
AU3046777A (en) 1979-05-17
DE2748920C2 (de) 1982-12-02
FR2370745B1 (pt) 1980-08-22
US4308207A (en) 1981-12-29
FI773273A (fi) 1978-05-11
SG66584G (en) 1985-03-15
SE435510B (sv) 1984-10-01
DK485677A (pt) 1978-05-11
IL53332A0 (en) 1978-01-31
SE7712387L (sv) 1978-05-10
BE860613A (fr) 1978-05-08
IE46262B1 (en) 1983-04-20
PT67247B (en) 1979-11-12
PH13515A (en) 1980-06-03
KE3472A (en) 1984-11-09
AU517829B2 (en) 1981-08-27
IL53332A (en) 1981-11-30
ATA799177A (de) 1981-09-15
CY1269A (en) 1984-11-23
JPS5359686A (en) 1978-05-29
DK140724C (pt) 1980-03-31
SU686616A3 (ru) 1979-09-15
PT67247A (en) 1977-12-01
IE46262L (en) 1978-05-10
NZ185642A (en) 1980-09-12
FI64143B (fi) 1983-06-30
MY8400056A (en) 1984-12-31
JPS5929076B2 (ja) 1984-07-18
NL7712171A (nl) 1978-05-12
FI64143C (fi) 1983-10-10
AT366682B (de) 1982-04-26
NL175297B (nl) 1984-05-16
HK32282A (en) 1982-07-23
NZ191043A (en) 1980-09-12

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PL Patent ceased