CH623578A5 - - Google Patents

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Publication number
CH623578A5
CH623578A5 CH545676A CH545676A CH623578A5 CH 623578 A5 CH623578 A5 CH 623578A5 CH 545676 A CH545676 A CH 545676A CH 545676 A CH545676 A CH 545676A CH 623578 A5 CH623578 A5 CH 623578A5
Authority
CH
Switzerland
Prior art keywords
trans
oxa
hydrogen
alkyl group
cis
Prior art date
Application number
CH545676A
Other languages
German (de)
English (en)
Inventor
Gerhardus Johannes Lourens
Johannes Mattheus Koekemoer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH623578A5 publication Critical patent/CH623578A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
CH545676A 1975-04-30 1976-04-30 CH623578A5 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA00752806A ZA752806B (en) 1975-04-30 1975-04-30 Novel 11-oxa-prostaglandin analogues derivatives thereof and methods for their preparation

Publications (1)

Publication Number Publication Date
CH623578A5 true CH623578A5 (ja) 1981-06-15

Family

ID=25568947

Family Applications (2)

Application Number Title Priority Date Filing Date
CH545676A CH623578A5 (ja) 1975-04-30 1976-04-30
CH153980A CH622020A5 (ja) 1975-04-30 1980-02-26

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH153980A CH622020A5 (ja) 1975-04-30 1980-02-26

Country Status (8)

Country Link
US (1) US4133817A (ja)
JP (1) JPS51133264A (ja)
AU (1) AU501804B2 (ja)
CA (1) CA1084059A (ja)
CH (2) CH623578A5 (ja)
DE (1) DE2618861A1 (ja)
GB (1) GB1540443A (ja)
ZA (1) ZA752806B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
JP3032302B2 (ja) 1995-12-22 2000-04-17 アルコン ラボラトリーズ,インコーポレイテッド 眼圧降下剤としてのプロスタグランジンの置換テトラヒドロフランアナログ
US5814660A (en) * 1995-12-22 1998-09-29 Alcon Laboratories, Inc. 9-oxa prostaglandin analogs as ocular hypotensives
US5866602A (en) * 1995-12-22 1999-02-02 Alcon Laboratories, Inc. Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
US6388128B1 (en) 1998-10-05 2002-05-14 Alcon Manufacturing, Ltd. Stannane synthesis of prostanoids
US6441196B2 (en) * 2000-05-19 2002-08-27 Alcon, Inc. Processes and novel intermediates for 11-oxa prostaglandin synthesis

Also Published As

Publication number Publication date
CH622020A5 (ja) 1981-03-13
ZA752806B (en) 1976-12-29
JPS51133264A (en) 1976-11-18
AU501804B2 (en) 1979-06-28
US4133817A (en) 1979-01-09
DE2618861A1 (de) 1976-11-11
GB1540443A (en) 1979-02-14
CA1084059A (en) 1980-08-19
AU1323976A (en) 1977-10-27

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Legal Events

Date Code Title Description
PL Patent ceased