ZA752806B - Novel 11-oxa-prostaglandin analogues derivatives thereof and methods for their preparation - Google Patents

Novel 11-oxa-prostaglandin analogues derivatives thereof and methods for their preparation

Info

Publication number
ZA752806B
ZA752806B ZA00752806A ZA752806A ZA752806B ZA 752806 B ZA752806 B ZA 752806B ZA 00752806 A ZA00752806 A ZA 00752806A ZA 752806 A ZA752806 A ZA 752806A ZA 752806 B ZA752806 B ZA 752806B
Authority
ZA
South Africa
Prior art keywords
oxa
novel
preparation
methods
prostaglandin analogues
Prior art date
Application number
ZA00752806A
Other languages
English (en)
Inventor
G Lourens
J Koekemoer
Original Assignee
Chembro Holdings Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chembro Holdings Pty Ltd filed Critical Chembro Holdings Pty Ltd
Priority to ZA00752806A priority Critical patent/ZA752806B/xx
Priority to US05/674,874 priority patent/US4133948A/en
Priority to AU13239/76A priority patent/AU501804B2/en
Priority to DE19762618861 priority patent/DE2618861A1/de
Priority to US05/681,742 priority patent/US4133817A/en
Priority to CA251,454A priority patent/CA1084059A/en
Priority to GB17811/76A priority patent/GB1540443A/en
Priority to JP51049771A priority patent/JPS51133264A/ja
Priority to CH545676A priority patent/CH623578A5/de
Publication of ZA752806B publication Critical patent/ZA752806B/xx
Priority to CH153980A priority patent/CH622020A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
ZA00752806A 1975-01-16 1975-04-30 Novel 11-oxa-prostaglandin analogues derivatives thereof and methods for their preparation ZA752806B (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ZA00752806A ZA752806B (en) 1975-04-30 1975-04-30 Novel 11-oxa-prostaglandin analogues derivatives thereof and methods for their preparation
US05/674,874 US4133948A (en) 1975-01-16 1976-04-08 Monosaccharides and products resulting therefrom
AU13239/76A AU501804B2 (en) 1975-04-30 1976-04-22 11-oza prostaglandins
DE19762618861 DE2618861A1 (de) 1975-04-30 1976-04-29 11-oxa-prostaglandinanaloga, ihre derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
US05/681,742 US4133817A (en) 1975-04-30 1976-04-29 11-Oxa-prostaglandin analogs
CA251,454A CA1084059A (en) 1975-04-30 1976-04-29 11-oxa-prostaglandin analogues
GB17811/76A GB1540443A (en) 1975-04-30 1976-04-30 11-oxaprostaglandins
JP51049771A JPS51133264A (en) 1975-04-30 1976-04-30 Novel 111oxaaprostaglandine homologue * derivatives and production of the same
CH545676A CH623578A5 (ja) 1975-04-30 1976-04-30
CH153980A CH622020A5 (ja) 1975-04-30 1980-02-26

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA00752806A ZA752806B (en) 1975-04-30 1975-04-30 Novel 11-oxa-prostaglandin analogues derivatives thereof and methods for their preparation

Publications (1)

Publication Number Publication Date
ZA752806B true ZA752806B (en) 1976-12-29

Family

ID=25568947

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00752806A ZA752806B (en) 1975-01-16 1975-04-30 Novel 11-oxa-prostaglandin analogues derivatives thereof and methods for their preparation

Country Status (8)

Country Link
US (1) US4133817A (ja)
JP (1) JPS51133264A (ja)
AU (1) AU501804B2 (ja)
CA (1) CA1084059A (ja)
CH (2) CH623578A5 (ja)
DE (1) DE2618861A1 (ja)
GB (1) GB1540443A (ja)
ZA (1) ZA752806B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5866602A (en) * 1995-12-22 1999-02-02 Alcon Laboratories, Inc. Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
EP0869794B1 (en) 1995-12-22 2004-08-11 Alcon Laboratories, Inc. Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
US5814660A (en) * 1995-12-22 1998-09-29 Alcon Laboratories, Inc. 9-oxa prostaglandin analogs as ocular hypotensives
WO2000020386A1 (en) * 1998-10-05 2000-04-13 Alcon Laboratories, Inc. Stannane synthesis of prostanoids
US6441196B2 (en) * 2000-05-19 2002-08-27 Alcon, Inc. Processes and novel intermediates for 11-oxa prostaglandin synthesis

Also Published As

Publication number Publication date
GB1540443A (en) 1979-02-14
CA1084059A (en) 1980-08-19
US4133817A (en) 1979-01-09
AU501804B2 (en) 1979-06-28
DE2618861A1 (de) 1976-11-11
JPS51133264A (en) 1976-11-18
CH622020A5 (ja) 1981-03-13
CH623578A5 (ja) 1981-06-15
AU1323976A (en) 1977-10-27

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