CH622269A5 - - Google Patents

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Publication number
CH622269A5
CH622269A5 CH1417576A CH1417576A CH622269A5 CH 622269 A5 CH622269 A5 CH 622269A5 CH 1417576 A CH1417576 A CH 1417576A CH 1417576 A CH1417576 A CH 1417576A CH 622269 A5 CH622269 A5 CH 622269A5
Authority
CH
Switzerland
Prior art keywords
group
support
side chains
preparation
reactive
Prior art date
Application number
CH1417576A
Other languages
English (en)
French (fr)
Inventor
Gerard Quash
Jacques Grange
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7534627A external-priority patent/FR2331567A1/fr
Priority claimed from FR7608966A external-priority patent/FR2345459A2/fr
Priority claimed from FR7625898A external-priority patent/FR2363108A2/fr
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of CH622269A5 publication Critical patent/CH622269A5/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14—Enzymes or microbial cells immobilised on or in an inorganic carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones
    • Y10S436/818—Human chorionic gonadotropin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/816—Attached to the carrier via a bridging agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyamides (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
CH1417576A 1975-11-13 1976-11-10 CH622269A5 (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7534627A FR2331567A1 (fr) 1975-11-13 1975-11-13 Nouveau procede de fixation chimique sur un support, de composes organiques comportant un residu glucidique et produits obtenus par ce procede
FR7608966A FR2345459A2 (fr) 1976-03-26 1976-03-26 Perfectionnements apportes aux supports solides sur lesquels sont couples des composes organiques et reactifs ainsi obtenus
FR7625898A FR2363108A2 (fr) 1976-08-27 1976-08-27 Perfectionnements apportes aux supports solides sur lesquels sont couples des composes organiques et reactifs ainsi obtenus

Publications (1)

Publication Number Publication Date
CH622269A5 true CH622269A5 (sv) 1981-03-31

Family

ID=27250547

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1417576A CH622269A5 (sv) 1975-11-13 1976-11-10

Country Status (8)

Country Link
US (2) US4217338A (sv)
JP (1) JPS5929817B2 (sv)
CA (1) CA1083508A (sv)
CH (1) CH622269A5 (sv)
DE (2) DE2661112C2 (sv)
GB (2) GB1571993A (sv)
NL (1) NL186656C (sv)
SE (3) SE7612482L (sv)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264766A (en) * 1877-09-19 1981-04-28 Hoffmann-La Roche Inc. Immunological diagnostic reagents
CA1083508A (fr) * 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
EP0001223A3 (en) * 1977-09-19 1979-12-12 F.Hoffmann-La Roche & Co. Aktiengesellschaft Latex coated with a polyhydroxy compound, process for the preparation of this latex, immunological reagent containing this latex, process for the preparation of this reagent, application of this reagent, testing procedure utilising this reagent and reagent kit containing this reagent
JPS5489019A (en) * 1977-11-29 1979-07-14 Mochida Pharm Co Ltd Immunochemical measuring reagent
JPS54113492A (en) * 1978-02-24 1979-09-05 Sanyo Chem Ind Ltd Preparation of glucoprotein derivative
JPS54147913A (en) * 1978-05-12 1979-11-19 Unitika Ltd Preparation of immunoadsorbent
US4278651A (en) * 1978-09-27 1981-07-14 Becton Dickinson & Company Supported receptor and use thereof in an assay
FR2450877A1 (fr) * 1979-03-06 1980-10-03 Inst Nat Sante Rech Med Nouveaux tests par agglutination pour la detection des virus de la grippe, et reactifs pour la realisation de ces tests
US4390517A (en) * 1979-12-19 1983-06-28 New England Nuclear Corporation Method, composition and kit for stabilizing radiolabeled compounds
US4358434A (en) * 1979-12-19 1982-11-09 New England Nuclear Corporation Method, composition and kit for stabilizing radiolabeled compounds
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
EP0056254A1 (en) * 1981-01-14 1982-07-21 David Eldon Wood Treatment of insoluble surfaces to inhibit nonspecific protein binding
CA1203164A (en) * 1982-03-09 1986-04-15 Thomas J. Mckearn Antibody conjugates
US5140104A (en) * 1982-03-09 1992-08-18 Cytogen Corporation Amine derivatives of folic acid analogs
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
US4867973A (en) * 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
US4511662A (en) * 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5258041A (en) * 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
US5217492A (en) * 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US4741900A (en) * 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
DE3311889A1 (de) * 1983-03-31 1984-10-11 Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach Verfahren zur irreversiblen bindung von protein an polystyroloberflaechen unter erhaltung der biologischen aktivitaet, so erhaltene polystyroloberflaechen und ihre verwendung
US4582810A (en) * 1983-09-30 1986-04-15 Becton, Dickinson And Company Immuno-agglutination particle suspensions
US4670406A (en) * 1984-01-06 1987-06-02 Becton Dickinson And Company Tracers for use in assays
US4523997A (en) * 1984-03-02 1985-06-18 J. T. Baker Chemical Company Affinity chromatography matrix with built-in reaction indicator
AU583854B2 (en) * 1984-09-13 1989-05-11 Cytogen Corporation Antibody therapeutic agent conjugates
US5430136A (en) * 1984-10-16 1995-07-04 Chiron Corporation Oligonucleotides having selectably cleavable and/or abasic sites
US4775619A (en) * 1984-10-16 1988-10-04 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US4560504A (en) * 1984-12-06 1985-12-24 Uop Inc. Carboxyl anchored immobilized antibodies
JPS61186857A (ja) * 1985-02-14 1986-08-20 Igaku Seibutsugaku Kenkyusho:Kk 酵素免疫測定用担体及び該担体を用いた酵素免疫測定法
US4818681A (en) * 1985-02-22 1989-04-04 Molecular Diagnostics, Inc. Fast and specific immobilization of nucleic acids to solid supports
DE3530312A1 (de) * 1985-08-24 1987-02-26 Guenther Dr Sawatzki Traeger fuer die photometrische immunspezifische bestimmung von antigenen oder antikoerpern, verfahren zu ihrer herstellung und verwendung
US4806631A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on solvolyzed nylon supports
DE3683650D1 (de) * 1985-10-24 1992-03-05 3I Research Exploit Ltd Biochemisches reagenzmittel.
FR2590674B1 (fr) * 1985-11-25 1989-03-03 Inst Nat Sante Rech Med Nouveaux reactifs de diagnostic
IL80973A (en) * 1985-12-20 1992-08-18 Sanofi Sa Modified ribosome-inactivating glycoproteins,their preparation,immunotoxins containing them and pharmaceutical compositions containing such immunotoxins
US4911911A (en) * 1985-12-20 1990-03-27 Sanofi Ribosome-inactivating glycoproteins, modified by oxidation of their osidic units and formation of a schiff's base and in-vivo prolonged action immunotoxins containing such a glycoprotein
JP2524511B2 (ja) * 1985-12-23 1996-08-14 ベツクマン インスツルメンツ インコ−ポレ−テツド 自動免疫化学分析装置及び方法
US4762710A (en) * 1986-06-16 1988-08-09 The United States Of America As Represented By The Department Of Health And Human Services Novel method of preparing toxoid by oxidation and metal ions
ATE88762T1 (de) * 1986-08-11 1993-05-15 Siska Diagnostics Inc Methoden und zusammensetzungen fuer tests mit nukleinsaeuresonden.
US5263992A (en) * 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4874813A (en) * 1987-02-09 1989-10-17 Shannessy Daniel J O Proteins bound to a marker or solid phase support matrix using a hydrazone linkage
US5260373A (en) * 1987-03-13 1993-11-09 Repligen Corporation Immobilized immunoglobulin-binding proteins
US5089605A (en) * 1987-03-13 1992-02-18 Repligen Corporation Immobilized immunoglobulin-binding proteins
US5241012A (en) 1987-05-19 1993-08-31 Applied Immune Sciences, Inc. Activated and conjugated polystyrene substrate
EP0303406A3 (en) * 1987-08-14 1991-07-03 Hewlett-Packard Company An immunoaffinity substrate
DE3738721C2 (de) * 1987-11-14 1995-10-05 Roehm Gmbh Immobilisierte Antikörper
US5047227A (en) * 1988-02-08 1991-09-10 Cytogen Corporation Novel and improved antibodies for site specific attachment of compounds
EP0353295B1 (en) * 1988-02-08 1994-04-06 Cytogen Corporation Novel and improved antibodies for site specific attachment of compounds
US4952519A (en) * 1988-05-02 1990-08-28 E. I. Du Pont De Nemours And Company Protein immobilization with poly(ethyleneimine) derivatized with a hydroprobic group
US5153166A (en) * 1988-08-18 1992-10-06 Trustees Of At Biochem Chromatographic stationary supports
US5258501A (en) * 1988-11-25 1993-11-02 Slobodan Barbaric Stabilization of glycoproteins
DE3909456A1 (de) * 1989-03-22 1990-09-27 Roehm Gmbh Verbessertes verfahren zur herstellung immobilisierter antikoerper
US4933410A (en) * 1989-03-29 1990-06-12 Applied Immunesciences, Inc. Covalent attachment of macromolecules on substrate surfaces
WO1991013358A1 (en) * 1990-02-23 1991-09-05 Bioquant, Inc. Stereochemically controlled immobilization of active molecules
US5082929A (en) * 1990-08-08 1992-01-21 Bioprobe International, Inc. Immobilization of glycocompounds and glycoconjugates
JPH06502766A (ja) * 1990-11-14 1994-03-31 アクゾ・ノベル・ナムローゼ・フェンノートシャップ ポリスチレン支持体ベース−サンドイッチハイブリダイゼーションアッセイ法を用いる核酸の非同位体検出およびそれに用いる組成物
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5654179A (en) * 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5620852A (en) * 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
DE69227112D1 (de) * 1991-07-16 1998-10-29 Transmed Biotech Inc Verfahren und zusammensetzungen für die gleichzeitige analyse einer vielzahl von analyten
US5424219A (en) * 1991-10-25 1995-06-13 Cytech Biomedical, Inc. Method of performing assays for biomolecules and solid supports for use in such methods
SE500964C2 (sv) * 1993-01-19 1994-10-10 Medicarb Ab Fast bärare med modifierad yta varvid modifikationen åstadkommes genom en primer innehållande en polysackarid och förfarande för framställning av en sådan bärare
JP3333309B2 (ja) * 1994-04-08 2002-10-15 鐘淵化学工業株式会社 ケトアミン含有タンパク質吸着体
US5532311A (en) * 1995-02-01 1996-07-02 Minnesota Mining And Manufacturing Company Process for modifying surfaces
US5583213A (en) * 1995-05-12 1996-12-10 Minnesota Mining And Manufacturing Company Process to activate sulfated polysaccharides
ATE240049T1 (de) * 1995-12-07 2003-05-15 Nestle Sa Herstellung von tee-extrakt
JPH09234317A (ja) * 1995-12-28 1997-09-09 Ngk Insulators Ltd ウィルス除去フィルター
GB2325233B (en) * 1997-05-16 2001-07-18 Norsk Hydro As Substrates having bound polysaccharides and bacterial nucleic acids
US6146771A (en) * 1997-07-01 2000-11-14 Terumo Cardiovascular Systems Corporation Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine
US6197289B1 (en) 1997-07-01 2001-03-06 Terumo Cardiovascular Systems Corporation Removal of biologically active agents
US5847110A (en) * 1997-08-15 1998-12-08 Biomedical Frontiers, Inc. Method of reducing a schiff base
AUPO888097A0 (en) * 1997-08-29 1997-09-25 Biotech Australia Pty Limited Cross-linked particles
NZ508172A (en) 1998-04-15 2003-08-29 Univ Utah State Real time detection of antigens
US7220596B2 (en) * 1998-04-15 2007-05-22 Utah State University Real time detection of antigens
US6087342A (en) * 1998-05-15 2000-07-11 Fmc Biopolymer As Substrates having bound polysaccharides and bacterial nucleic acids
US20050043506A1 (en) * 2000-09-27 2005-02-24 Michigan Biotechnology Institute Polyamide materials based on unsaturated carboxylic acids and amines
US6797743B2 (en) * 2000-09-27 2004-09-28 Michigan Biotechnology Institute Antimicrobial polymer
US6509104B2 (en) 2000-12-05 2003-01-21 Michigan Biotechnology Institute Antithrombogenic polymer coating
US6939554B2 (en) 2002-02-05 2005-09-06 Michigan Biotechnology Institute Antimicrobial polymer
US7204940B2 (en) 2002-03-20 2007-04-17 Michigan Biotechnology Institute Conductive polymer-based material
US6951902B2 (en) * 2002-08-16 2005-10-04 Michigan Biotechnology Institute Two dimensional polymer that generates nitric oxide
FR2855613B1 (fr) * 2003-05-26 2005-08-19 Biocytex Procede de detection et de quantification multiplex d'analytes dans un echantillon a l'aide de microspheres
US8475652B2 (en) * 2009-10-19 2013-07-02 Jan A. K. Paul Method for purification of uncatalyzed natural fuels from metal ions by means of at least one hemeprotein and use of the at least on hemeprotein
US11754563B2 (en) * 2014-11-20 2023-09-12 Global Life Sciences Solutions Operations UK Ltd Porous membranes with a polymer grafting, methods and uses thereof
CN104610387A (zh) * 2015-01-22 2015-05-13 厦门大学 基于含磷苯胺衍生物的寡糖非还原胺化衍生化方法
CN108884152A (zh) 2016-01-29 2018-11-23 尔察祯有限公司 鉴定结合细胞表面表位的抗体的筛选方法
WO2018140827A1 (en) 2017-01-27 2018-08-02 Achaogen, Inc. Reporter microorganisms and uses thereof
CN110118848A (zh) * 2019-05-17 2019-08-13 厦门大学 磷胺类寡糖非还原胺化衍生试剂及其寡糖衍生化方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE29474E (en) 1966-06-02 1977-11-15 Pharmacia Ab Method for the determination of proteins and polypeptides
US3505785A (en) * 1967-06-20 1970-04-14 Du Pont Superficially porous supports for chromatography
US3553310A (en) * 1967-12-28 1971-01-05 Miles Lab Immunologically reactive particles
CH538003A (fr) * 1968-03-29 1973-01-31 Anvar Procédé pour l'obtention d'articles textiles porteurs d'enzymes
US3519538A (en) * 1968-09-05 1970-07-07 Corning Glass Works Chemically coupled enzymes
US3857931A (en) * 1971-02-01 1974-12-31 Hoffmann La Roche Latex polymer reagents for diagnostic tests
SE401955B (sv) * 1971-05-12 1978-06-05 Behringwerke Ag For anvendning som diagnostiskt reagens avsedd reaktionsprodukt mellan polystyren i latexform och ett protein eller en peptid jemte forfarande for dess framstellning
US3853987A (en) * 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
DE2215249C3 (de) * 1972-03-29 1979-02-08 Hoechst Ag, 6000 Frankfurt Verfahren zum kontinuierlichen Färben von hochwertigen Polyesterfasern
DE2247163A1 (de) * 1972-09-26 1974-03-28 Merck Patent Gmbh Traegermatrix zur fixierung biologisch wirksamer stoffe und verfahren zu ihrer herstellung
DE2357794A1 (de) * 1972-11-22 1974-06-06 Brenner Max Verfahren zur herstellung von traegerfixierten aminoverbindungen
JPS5121837B2 (sv) * 1973-05-18 1976-07-05
CS175047B1 (sv) * 1974-04-25 1977-04-29
US3947352A (en) * 1974-05-31 1976-03-30 Pedro Cuatrecasas Polysaccharide matrices for use as adsorbents in affinity chromatography techniques
US3970521A (en) * 1974-08-07 1976-07-20 Exxon Research And Engineering Company Immobilized glycoenzymes
US4001583A (en) * 1974-10-04 1977-01-04 Barrett M James Covalently bound biological substances to plastic materials and use in radioassay
CA1083508A (fr) * 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
US4081245A (en) * 1976-05-03 1978-03-28 Beckman Instruments, Inc. Immunoassay procedure employing novel immunochemical composites
US4081246A (en) * 1976-05-03 1978-03-28 Beckman Instruments, Inc. Solid phase column immunoassay procedure employing novel immunochemical composites
DE2621974A1 (de) * 1976-05-18 1977-11-24 Max Planck Gesellschaft Verfahren zur herstellung eines zur kovalenten bindung mit biologisch aktivem material befaehigten traegermaterials

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CA1083508A (fr) 1980-08-12
JPS52104591A (en) 1977-09-02
NL186656B (nl) 1990-08-16
NL186656C (nl) 1991-01-16
SE8107631L (sv) 1981-12-18
US4217338A (en) 1980-08-12
NL7612680A (nl) 1977-05-17
JPS5929817B2 (ja) 1984-07-23
SE7612482L (sv) 1977-05-13
GB1571993A (en) 1980-07-23
US4419444A (en) 1983-12-06
GB1571992A (en) 1980-07-23
DE2651680A1 (de) 1977-05-26
DE2661112C2 (de) 1991-08-29
SE8107632L (sv) 1981-12-18

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