CH621341A5 - - Google Patents

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Publication number
CH621341A5
CH621341A5 CH1504875A CH1504875A CH621341A5 CH 621341 A5 CH621341 A5 CH 621341A5 CH 1504875 A CH1504875 A CH 1504875A CH 1504875 A CH1504875 A CH 1504875A CH 621341 A5 CH621341 A5 CH 621341A5
Authority
CH
Switzerland
Prior art keywords
formula
alkali metal
mixture
tetrahydroisoquinoline
temperature
Prior art date
Application number
CH1504875A
Other languages
German (de)
English (en)
Inventor
Muneyoshi Ikezaki
Kunihiko Irie
Norihide Umino
Katsuo Ikezawa
Masanori Sato
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of CH621341A5 publication Critical patent/CH621341A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CH1504875A 1974-11-20 1975-11-20 CH621341A5 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49134734A JPS5247474B2 (nl) 1974-11-20 1974-11-20

Publications (1)

Publication Number Publication Date
CH621341A5 true CH621341A5 (nl) 1981-01-30

Family

ID=15135331

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1504875A CH621341A5 (nl) 1974-11-20 1975-11-20
CH606580A CH623039A5 (nl) 1974-11-20 1980-08-11

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH606580A CH623039A5 (nl) 1974-11-20 1980-08-11

Country Status (12)

Country Link
US (1) US4054659A (nl)
JP (1) JPS5247474B2 (nl)
BE (1) BE835744A (nl)
CA (1) CA1032541A (nl)
CH (2) CH621341A5 (nl)
CS (1) CS190503B2 (nl)
DK (1) DK143197C (nl)
FR (1) FR2291753A1 (nl)
GB (1) GB1487457A (nl)
HU (1) HU170648B (nl)
NL (1) NL166469C (nl)
SE (1) SE424638B (nl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5817465B2 (ja) * 1977-09-02 1983-04-07 田辺製薬株式会社 テトラヒドロイソキノリン誘導体の製法
JPS5484035A (en) * 1977-12-16 1979-07-04 Tanabe Seiyaku Co Ltd Anti-allergic agent
AU9512298A (en) * 1997-09-30 1999-04-23 Molecular Design International, Inc. Beta3-adrenoreceptor agonists, agonist compositions and methods of using
DE60223904T2 (de) 2001-01-26 2008-11-27 Btg International Ltd. Benzylaminanalogen
US6593341B2 (en) 2001-03-29 2003-07-15 Molecular Design International, Inc. β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same
US6596734B1 (en) 2002-10-11 2003-07-22 Molecular Design International, Inc. Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3873704A (en) * 1970-12-17 1975-03-25 Tanabe Seiyaku Co Novel tetrahydroisoquinoline compounds in a pharmaceutical composition
JPS5734275B2 (nl) * 1973-07-30 1982-07-22

Also Published As

Publication number Publication date
HU170648B (nl) 1977-07-28
JPS5170770A (nl) 1976-06-18
GB1487457A (en) 1977-09-28
NL166469B (nl) 1981-03-16
DE2551924B2 (de) 1977-05-26
JPS5247474B2 (nl) 1977-12-02
SE424638B (sv) 1982-08-02
DE2551924A1 (de) 1976-05-26
FR2291753B1 (nl) 1978-11-10
DK143197C (da) 1981-11-23
AU8671375A (en) 1977-03-17
DK487375A (da) 1976-05-21
NL7513517A (nl) 1976-05-24
SE7513013L (sv) 1976-05-21
US4054659A (en) 1977-10-18
CS190503B2 (en) 1979-05-31
CH623039A5 (nl) 1981-05-15
CA1032541A (en) 1978-06-06
DK143197B (da) 1981-07-20
FR2291753A1 (fr) 1976-06-18
NL166469C (nl) 1981-08-17
BE835744A (fr) 1976-03-16

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Legal Events

Date Code Title Description
PL Patent ceased