CH621123A5 - - Google Patents

Download PDF

Info

Publication number
CH621123A5
CH621123A5 CH595476A CH595476A CH621123A5 CH 621123 A5 CH621123 A5 CH 621123A5 CH 595476 A CH595476 A CH 595476A CH 595476 A CH595476 A CH 595476A CH 621123 A5 CH621123 A5 CH 621123A5
Authority
CH
Switzerland
Prior art keywords
formula
phenyl
alkyl
cephem
thienyl
Prior art date
Application number
CH595476A
Other languages
German (de)
English (en)
Inventor
Wayne Alfred Spitzer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CH621123A5 publication Critical patent/CH621123A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CH595476A 1975-05-12 1976-05-12 CH621123A5 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/576,818 US4013651A (en) 1975-05-12 1975-05-12 3-substituted amino-cephalosporins

Publications (1)

Publication Number Publication Date
CH621123A5 true CH621123A5 (no) 1981-01-15

Family

ID=24306128

Family Applications (3)

Application Number Title Priority Date Filing Date
CH595376A CH623054A5 (no) 1975-05-12 1976-05-12
CH595476A CH621123A5 (no) 1975-05-12 1976-05-12
CH595576A CH619958A5 (no) 1975-05-12 1976-05-12

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH595376A CH623054A5 (no) 1975-05-12 1976-05-12

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH595576A CH619958A5 (no) 1975-05-12 1976-05-12

Country Status (11)

Country Link
US (3) US4013651A (no)
JP (1) JPS51138697A (no)
BE (1) BE841496A (no)
CA (1) CA1074782A (no)
CH (3) CH623054A5 (no)
DE (1) DE2620308A1 (no)
ES (3) ES447806A1 (no)
GB (1) GB1544984A (no)
IE (1) IE42540B1 (no)
IL (1) IL49318A (no)
NL (3) NL7605078A (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947413A (en) * 1972-11-13 1976-03-30 Merck & Co., Inc. 3-α-Substituted cephalosporins
US4550162A (en) * 1975-02-20 1985-10-29 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
JPS543087A (en) * 1977-06-03 1979-01-11 Fujisawa Pharmaceut Co Ltd Preparation of cephalosporin compound
US4244885A (en) * 1977-12-08 1981-01-13 Yeda Research And Development Co. Ltd. α-Substituted-3-(halomethyl)-4-hydroxybenzeneacetic acids
US4436903A (en) * 1980-12-22 1984-03-13 Ciba-Geigy Corporation Process for the production of 7 β-substituted-3-unsubstituted-3-cephem-4-carboxylic acid compounds
US4533497A (en) * 1982-12-27 1985-08-06 Eli Lilly And Company N-ethylidene azetidinones
US5019571A (en) * 1988-01-25 1991-05-28 Eli Lilly And Company 1-carbacephalosporin antibiotics
JPH021487A (ja) * 1988-01-25 1990-01-05 Eli Lilly & Co １―カルバセファロスポリン抗生物質
WO2017190043A1 (en) * 2016-04-29 2017-11-02 University Of Kansas Cephalosporin-type compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE412238B (sv) * 1971-05-24 1980-02-25 Ciba Geigy Forfarande for framstellning av 7 beta-amino-cefem-4-karboxylsyraforeningar genom dekarbonylering av en 3-formyl-cefem-4-karboxylsyraforening
US4001226A (en) * 1974-12-04 1977-01-04 Eli Lilly And Company 3-(substituted)carbonylamino cephem derivatives
JPS609516B2 (ja) * 1975-03-07 1985-03-11 塩野義製薬株式会社 セフエム骨格の環化製法
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen

Also Published As

Publication number Publication date
JPS51138697A (en) 1976-11-30
NL7605075A (nl) 1976-11-16
GB1544984A (en) 1979-04-25
US4013651A (en) 1977-03-22
ES447805A1 (es) 1978-04-01
CH623054A5 (no) 1981-05-15
ES447806A1 (es) 1977-10-01
IE42540B1 (en) 1980-08-27
CA1074782A (en) 1980-04-01
IE42540L (en) 1976-11-12
NL7605078A (nl) 1976-11-16
US4065621A (en) 1977-12-27
DE2620308A1 (de) 1976-11-25
IL49318A (en) 1980-03-31
NL7605077A (nl) 1976-11-16
CH619958A5 (no) 1980-10-31
ES447807A1 (es) 1977-10-01
US4065618A (en) 1977-12-27
IL49318A0 (en) 1976-05-31
BE841496A (fr) 1976-11-08

Similar Documents

Publication Publication Date Title
CH620216A5 (no)
CH621123A5 (no)
AT392072B (de) Verfahren zur herstellung der neuen 7-amino-3propenylcephalosporansaeure sowie von estern und salzen derselben
DE2725712A1 (de) Verfahren zur reduktion von cephalosporinsulfoxiden
DE3216256C2 (no)
CH623331A5 (en) Process for the preparation of 7beta-amino- and 7beta-acylamino-6alphaH-8-oxo-4-thia-1-azabicyclo[4.2.0]oct-2-ene-2-ca rboxylic acid derivatives
DE2417988A1 (de) Verfahren zur herstellung von 7-acylamido-3-fluor-3-cephem-4-carbonsaeureestern und -saeuren
CH642968A5 (de) Cephalosporin-analoge und verfahren zu deren herstellung.
DE2163789A1 (de) Verfahren zur Herstellung von Cephalosporinderivaten
CH617205A5 (no)
DE69305904T2 (de) Benzo(b)Thiophen-5-Ylderivat und Verfahren zu seiner Herstellung
DE2534926A1 (de) Sauerstoffanaloge von cephalosporinen
DE2442540C2 (de) Verfahren zur Herstellung von 6-Alkoxy-6-benzylidenaminopenam-und 7-Alkoxy-7-benzylidenaminocephemverbindungen
DD201588A5 (de) Verfahren zur herstellung von 1-cyanomethyl-1h-tetrazol-5-thiol
CH630634A5 (de) Verfahren zur herstellung von 7-beta-(2-oxyimino-2-arylacetamido)-cephalosporine.
DE2337105A1 (de) Antibiotika und verfahren zu ihrer herstellung
DE3212613C2 (no)
AT340592B (de) Verfahren zur herstellung von neuen dl-7-azidocephalosporinverbindungen
EP0261668B1 (de) Verfahren zur Herstellung von 4-Alkoxy-2(5H)-thiophenonen
DE2417987A1 (de) Cephalosporinsulfonatester und verfahren zu ihrer herstellung
US4008228A (en) Process for preparing 3-methyl-3-cephem antibiotics
AT384215B (de) Verfahren zur herstellung von neuen, heterocyclischen essigsaeuren
DE2134439A1 (de) Antibakterielle Mittel und Verfahren zu deren Herstellung
CH601314A5 (en) Antibacterial alkanoyloxymethyl cephalosporin esters
AT331984B (de) Verfahren zur herstellung eines neuen derivates der 7-monochlor-acetamido -3- desacetoxy-cephalosporansaure

Legal Events

Date Code Title Description
PL Patent ceased