CH620907A5 - Process for the preparation of antimicrobial bispyridinium derivatives - Google Patents

Process for the preparation of antimicrobial bispyridinium derivatives Download PDF

Info

Publication number
CH620907A5
CH620907A5 CH233677A CH233677A CH620907A5 CH 620907 A5 CH620907 A5 CH 620907A5 CH 233677 A CH233677 A CH 233677A CH 233677 A CH233677 A CH 233677A CH 620907 A5 CH620907 A5 CH 620907A5
Authority
CH
Switzerland
Prior art keywords
bis
pyridinium
mol
dibromide
pyridine
Prior art date
Application number
CH233677A
Other languages
English (en)
French (fr)
Inventor
Denis Bailey
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/734,729 external-priority patent/US4107313A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of CH620907A5 publication Critical patent/CH620907A5/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
CH233677A 1976-02-25 1977-02-24 Process for the preparation of antimicrobial bispyridinium derivatives CH620907A5 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66110176A 1976-02-25 1976-02-25
US66112876A 1976-02-25 1976-02-25
US72131576A 1976-09-07 1976-09-07
US05/734,729 US4107313A (en) 1976-02-25 1976-10-22 α,α-Bis-[4-(R-amino)-1-pyridinium]xylenes and antibacterial and antifungal uses

Publications (1)

Publication Number Publication Date
CH620907A5 true CH620907A5 (en) 1980-12-31

Family

ID=27505307

Family Applications (1)

Application Number Title Priority Date Filing Date
CH233677A CH620907A5 (en) 1976-02-25 1977-02-24 Process for the preparation of antimicrobial bispyridinium derivatives

Country Status (23)

Country Link
JP (1) JPS6033108B2 (de)
AR (2) AR214876A1 (de)
AT (1) AT355571B (de)
AU (1) AU510149B2 (de)
BE (1) BE851807A (de)
CA (1) CA1073911A (de)
CH (1) CH620907A5 (de)
DE (1) DE2708331A1 (de)
DK (1) DK147638C (de)
ES (1) ES456252A1 (de)
FI (1) FI66850C (de)
FR (1) FR2342286A1 (de)
GB (1) GB1533952A (de)
HK (1) HK67484A (de)
IE (1) IE45336B1 (de)
IL (1) IL51520A (de)
LU (1) LU76837A1 (de)
MX (1) MX5132E (de)
NL (1) NL186086C (de)
NO (2) NO148779C (de)
PH (2) PH22315A (de)
PT (1) PT66224B (de)
SE (1) SE432421B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32300E (en) * 1979-08-13 1986-12-02 Sterling Drug Inc. Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use thereof
US4420484A (en) 1979-08-13 1983-12-13 Sterling Drug Inc. Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use therof
DE19647402A1 (de) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE19647413A1 (de) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE19647317A1 (de) * 1996-11-15 1998-05-20 Hoechst Schering Agrevo Gmbh Substituierte Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
DE10005853C1 (de) * 2000-02-10 2002-02-07 Schuelke & Mayr Gmbh Verfahren zur Herstellung von Bis-(4-amino-1-pyridinium)-alkanen
DE10205883A1 (de) * 2002-02-13 2003-08-21 Schuelke & Mayr Gmbh Wässriges Antiseptikum auf Basis von Bispyridiniumalkanen
TWI278315B (en) * 2003-06-13 2007-04-11 Ind Tech Res Inst A compound having anti-virus activity
ES2237332B1 (es) * 2004-01-14 2006-11-01 Consejo Sup. Investig. Cientificas Derivados de piridinio y quinolinio.
DE102005002645A1 (de) 2005-01-19 2006-07-20 Schülke & Mayr GmbH Alkoholische Zusammensetzungen für die Desinfektion
DE102005002644A1 (de) * 2005-01-19 2006-07-20 Schülke & Mayr GmbH Zusammensetzungen für die hygienische Händedesinfektion und die desinfizierende Händewaschung
DE102005002643B4 (de) * 2005-01-19 2007-11-22 Schülke & Mayr GmbH Zusammensetzungen für die hygienische Händedesinfektion und die desinfizierende Händewaschung
DE102005045145A1 (de) * 2005-09-15 2007-03-29 Schülke & Mayr GmbH Verwendung von Octenidindihydrochlorid in halbfesten Zubereitungen
DE102005063375A1 (de) * 2005-09-15 2007-04-19 Schülke & Mayr GmbH Antimikrobielle Zubereitungen mit einem Gehalt an Octenidindihydrochlorid verkapselt in Liposomen
DE102005048131A1 (de) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Antimikrobielle Kunststoffzusammensetzung mit niedriger Elutionsrate und langer Wirksamkeit
DE102005048132A1 (de) * 2005-10-06 2007-04-12 Bayer Innovation Gmbh Verfahren zur Herstellung antimikrobieller Kunststoffzusammensetzungen
DE102006012991A1 (de) 2006-03-22 2007-10-11 Bayer Innovation Gmbh Verfahren und Vorrichtung zum optischen Auslesen von Informationen
DE102006051891A1 (de) 2006-10-31 2008-05-08 Schülke & Mayr GmbH Antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
DE102008011691A1 (de) 2008-02-28 2009-09-10 Schülke & Mayr GmbH Stabilisierte, antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
DE102009049504A1 (de) 2009-10-15 2011-04-21 Schülke & Mayr GmbH Wund- und Schleimhautantiseptikum auf der Basis von Bispyridiniumalkanen
DE202010007433U1 (de) 2010-04-20 2011-06-01 Klosterfrau Berlin GmbH, 12277 Gel, insbesondere Gleitgel
EP2384733B1 (de) * 2010-05-07 2016-07-27 Ivoclar Vivadent AG Antimikrobielle Dentalwerkstoffe
DE102010025932A1 (de) 2010-07-02 2012-01-05 Schülke & Mayr GmbH Antiseptikum auf der Basis von Bispyridiniumalkanen
DE102011077432A1 (de) * 2011-06-10 2012-12-13 Schülke & Mayr GmbH Verwendung von Bispyridiniumalkanen zur Abtötung von Sporen
DE102012215511A1 (de) 2012-08-31 2014-06-12 Schülke & Mayr GmbH Verfahren zur Herstellung einer Bispyridiniumalkan enthaltenden halbfesten Zubereitung
DE102013223657A1 (de) 2013-11-20 2015-05-21 Schülke & Mayr GmbH Kit für die Erzeugung von Bispyridiniumalkan enthaltenden Schäumen
DE102014107413A1 (de) 2014-05-26 2015-11-26 Schülke & Mayr GmbH Kit für das Einfärben von desinfizierten Bereichen einer Oberfläche
DE102014107412A1 (de) 2014-05-26 2015-12-17 Schülke & Mayr GmbH Gefärbte desinfizierende Zubereitung auf Basis von Bispyridiniumalkan
DE102014115080A1 (de) 2014-10-16 2016-04-21 Schülke & Mayr GmbH Verwendung von Fettsäureester zur Verbesserung der antimikrobiellen Wirksamkeit eines alkoholischen Desinfektionsmittels
CA3072030A1 (en) * 2017-08-21 2019-02-28 Dishman Carbogen Amcis Ltd. Octenidine based compounds
EP3771337A1 (de) 2019-07-29 2021-02-03 The Procter & Gamble Company Antimikrobielle zusammensetzung
EP3771339A1 (de) 2019-07-29 2021-02-03 The Procter & Gamble Company Desinfizierende zusammensetzung
EP3771741A1 (de) 2019-07-29 2021-02-03 The Procter & Gamble Company Textilbehandlung
EP3771770A1 (de) 2019-07-29 2021-02-03 The Procter & Gamble Company Antimikrobielle erfrischungszusammensetzungen
EP3771338A1 (de) 2019-07-29 2021-02-03 The Procter & Gamble Company Saure antimikrobielle zusammensetzung
EP3816272B1 (de) 2019-10-31 2023-11-01 The Procter & Gamble Company Zusammensetzung für die gewebepflege
CN114989076A (zh) * 2022-06-07 2022-09-02 八叶草健康产业研究院(厦门)有限公司 一种奥替尼啶碱的制备方法

Also Published As

Publication number Publication date
NO148779B (no) 1983-09-05
NO148779C (no) 1983-12-14
IE45336B1 (en) 1982-08-11
MX5132E (es) 1983-03-28
PT66224B (en) 1978-07-14
SE432421B (sv) 1984-04-02
JPS52105228A (en) 1977-09-03
DK147638B (da) 1984-10-29
PH22315A (en) 1988-07-29
AT355571B (de) 1980-03-10
NO150758C (no) 1984-12-12
DK147638C (da) 1985-07-15
PT66224A (en) 1977-03-01
FI66850C (fi) 1984-12-10
SE7702072L (sv) 1977-10-10
IL51520A0 (en) 1977-04-29
NO150758B (no) 1984-09-03
BE851807A (fr) 1977-08-25
AR214876A1 (es) 1979-08-15
HK67484A (en) 1984-09-07
FR2342286B1 (de) 1979-03-09
IL51520A (en) 1980-12-31
FI66850B (fi) 1984-08-31
FR2342286A1 (fr) 1977-09-23
AU2258277A (en) 1978-08-31
ATA129777A (de) 1979-08-15
CA1073911A (en) 1980-03-18
NL7701965A (nl) 1977-08-29
NO823274L (no) 1977-08-26
IE45336L (en) 1977-08-25
LU76837A1 (de) 1977-09-12
PH25097A (en) 1991-02-19
GB1533952A (en) 1978-11-29
DK81277A (da) 1977-08-26
NO770631L (no) 1977-08-26
JPS6033108B2 (ja) 1985-08-01
AR218052A1 (es) 1980-05-15
NL186086C (nl) 1990-09-17
FI770593A (de) 1977-08-26
DE2708331A1 (de) 1977-09-08
DE2708331C2 (de) 1991-03-21
ES456252A1 (es) 1978-02-01
NL186086B (nl) 1990-04-17
AU510149B2 (en) 1980-06-12

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PL Patent ceased
PUE Assignment

Owner name: STERLING DRUG INC. TRANSFER- SANOFI