CH619233A5 - - Google Patents

Download PDF

Info

Publication number
CH619233A5
CH619233A5 CH1000175A CH1000175A CH619233A5 CH 619233 A5 CH619233 A5 CH 619233A5 CH 1000175 A CH1000175 A CH 1000175A CH 1000175 A CH1000175 A CH 1000175A CH 619233 A5 CH619233 A5 CH 619233A5
Authority
CH
Switzerland
Prior art keywords
group
amino
protected
compound
cephem
Prior art date
Application number
CH1000175A
Other languages
German (de)
English (en)
Inventor
Peter Dr Schneider
Hans Dr Bickel
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH1000175A priority Critical patent/CH619233A5/de
Priority to US05/705,221 priority patent/US4089955A/en
Priority to PT65406A priority patent/PT65406B/pt
Priority to FR7622697A priority patent/FR2319365A1/fr
Priority to DE2633637A priority patent/DE2633637C2/de
Priority to GB31654/76A priority patent/GB1551785A/en
Priority to IL50166A priority patent/IL50166A/xx
Priority to CA258,055A priority patent/CA1089444A/en
Priority to ES450276A priority patent/ES450276A1/es
Priority to SE7608585A priority patent/SE427661B/xx
Priority to GR51375A priority patent/GR60801B/el
Priority to AU16364/76A priority patent/AU500539B2/en
Priority to DK345076A priority patent/DK345076A/da
Priority to AT542676A priority patent/AT345980B/de
Priority to BE169405A priority patent/BE844713A/xx
Priority to NO762655A priority patent/NO762655L/no
Priority to NZ181626A priority patent/NZ181626A/xx
Priority to AT563476A priority patent/AT344903B/de
Priority to NL7608526A priority patent/NL7608526A/nl
Priority to ZA764613A priority patent/ZA764613B/xx
Priority to DD7600194157A priority patent/DD128526A5/xx
Priority to IE1700/76A priority patent/IE43149B1/en
Priority to JP51090871A priority patent/JPS594437B2/ja
Priority to AT542677A priority patent/ATA542677A/de
Priority to CH953179A priority patent/CH622266A5/de
Publication of CH619233A5 publication Critical patent/CH619233A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
CH1000175A 1975-07-31 1975-07-31 CH619233A5 (nl)

Priority Applications (25)

Application Number Priority Date Filing Date Title
CH1000175A CH619233A5 (nl) 1975-07-31 1975-07-31
US05/705,221 US4089955A (en) 1975-07-31 1976-07-14 7-β-[D-2-Amino-2-(1,4-cyclohexadienyl)-acetylamino]-3-Hal-3-cephem-4-carboxylic acids
PT65406A PT65406B (en) 1975-07-31 1976-07-23 Process for the preparation of insaturated aliphatic halogenated heterocyclics
FR7622697A FR2319365A1 (fr) 1975-07-31 1976-07-26 Heterocycles halogenes a insaturation aliphatique
DE2633637A DE2633637C2 (de) 1975-07-31 1976-07-27 7β-[D-2-Amino-2-(1,4-cyclohexadienyl)-acetylamino] -3-hal-3-cephem-4-carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
GB31654/76A GB1551785A (en) 1975-07-31 1976-07-29 7-amino-acylamino-3-halo-cephem compounds
IL50166A IL50166A (en) 1975-07-31 1976-07-29 7 -(d-2-amino-(1,4-cyclohexadienyl)-acetylamino)-3-hal-3-cephem-4-carboxylic acids their preparation and pharmaceutical compositions containing them
CA258,055A CA1089444A (en) 1975-07-31 1976-07-29 Unsaturated aliphatic halogenated heterocyclic compounds
ES450276A ES450276A1 (es) 1975-07-31 1976-07-29 Procedimiento para la obtencion de acido 7 beta-(d-2-(amino-2, 1, 4-ciclohexadienil)-acetilamino)-3-hal-3-cefem-4-carbo-xilicos.
SE7608585A SE427661B (sv) 1975-07-31 1976-07-29 Analogiforfarande for framstellning av 7 beta-(d-2-amino-2-(1,4-cyklohexadienyl)-acetyl-amino)-3-klor-3-cetem-4-karboxylsyra
GR51375A GR60801B (en) 1975-07-31 1976-07-29 Preparation process of unsaturated,aliphatic,halogen-heterocyclic compounds
AU16364/76A AU500539B2 (en) 1975-07-31 1976-07-29 78-[d-2-amino-2(1,4-cyclohexadienyl)-acetylamino]-3-halo-3-cephem-4-carboxylic acids
DK345076A DK345076A (da) 1975-07-31 1976-07-30 Fremgangsmade til fremstilling af umettet-aliphatiske halogen-heterocycler og anvendelse deraf
AT542676A AT345980B (de) 1975-07-31 1976-07-30 Verfahren zur herstellung von neuen cephalosporinen
BE169405A BE844713A (fr) 1975-07-31 1976-07-30 Styphnate de plomb, sa preparation et son utilisation
NO762655A NO762655L (nl) 1975-07-31 1976-07-30
NZ181626A NZ181626A (en) 1975-07-31 1976-07-30 3-holo-cephalosporins and pharmaceutical compositions
AT563476A AT344903B (de) 1975-07-31 1976-07-30 Verfahren zur herstellung von neuen cephalosporinen
NL7608526A NL7608526A (nl) 1975-07-31 1976-07-30 Werkwijze voor het bereiden van onverzadigd- -alifatische halogeen bevattende heterocycli- sche verbindingen.
ZA764613A ZA764613B (en) 1975-07-31 1976-07-30 Unsaturated aliphatic halogenated heterocyclic compounds
DD7600194157A DD128526A5 (de) 1975-07-31 1976-07-30 Verfahren zur herstellung von ungesaettigt-aliphatischen halogen-heterocyclen
IE1700/76A IE43149B1 (en) 1975-07-31 1976-07-30 7-amino-acylamino-3-halo-cephem compounds
JP51090871A JPS594437B2 (ja) 1975-07-31 1976-07-31 ３−ハロゲノ−３−セフエム−４−カルボン酸またはその塩の製法およびこれら化合物を含む医薬用配合物
AT542677A ATA542677A (de) 1975-07-31 1977-07-26 Verfahren zur herstellung von neuen cephalosporinen
CH953179A CH622266A5 (nl) 1975-07-31 1979-10-24

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1000175A CH619233A5 (nl) 1975-07-31 1975-07-31

Publications (1)

Publication Number Publication Date
CH619233A5 true CH619233A5 (nl) 1980-09-15

Family

ID=4358303

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1000175A CH619233A5 (nl) 1975-07-31 1975-07-31
CH953179A CH622266A5 (nl) 1975-07-31 1979-10-24

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH953179A CH622266A5 (nl) 1975-07-31 1979-10-24

Country Status (22)

Country Link
US (1) US4089955A (nl)
JP (1) JPS594437B2 (nl)
AT (1) AT344903B (nl)
AU (1) AU500539B2 (nl)
BE (1) BE844713A (nl)
CA (1) CA1089444A (nl)
CH (2) CH619233A5 (nl)
DD (1) DD128526A5 (nl)
DE (1) DE2633637C2 (nl)
DK (1) DK345076A (nl)
ES (1) ES450276A1 (nl)
FR (1) FR2319365A1 (nl)
GB (1) GB1551785A (nl)
GR (1) GR60801B (nl)
IE (1) IE43149B1 (nl)
IL (1) IL50166A (nl)
NL (1) NL7608526A (nl)
NO (1) NO762655L (nl)
NZ (1) NZ181626A (nl)
PT (1) PT65406B (nl)
SE (1) SE427661B (nl)
ZA (1) ZA764613B (nl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS564623B2 (nl) * 1972-12-25 1981-01-31
JPS5338694A (en) * 1976-09-18 1978-04-08 Toyo Jozo Co Ltd Novel alpha-amino-3-chlorocephem compound and method of preparing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3819620A (en) * 1972-06-01 1974-06-25 Squibb & Sons Inc 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate
YU36970B (en) * 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins

Also Published As

Publication number Publication date
US4089955A (en) 1978-05-16
AT344903B (de) 1978-08-25
NZ181626A (en) 1978-03-06
DE2633637A1 (de) 1977-02-17
CH622266A5 (nl) 1981-03-31
AU1636476A (en) 1978-02-02
ZA764613B (en) 1977-08-31
JPS594437B2 (ja) 1984-01-30
AU500539B2 (en) 1979-05-24
CA1089444A (en) 1980-11-11
FR2319365A1 (fr) 1977-02-25
GR60801B (en) 1978-08-30
JPS5217491A (en) 1977-02-09
PT65406A (en) 1976-08-01
IL50166A (en) 1979-07-25
IE43149B1 (en) 1980-12-31
SE427661B (sv) 1983-04-25
DE2633637C2 (de) 1982-04-22
GB1551785A (en) 1979-08-30
DD128526A5 (de) 1977-11-23
IE43149L (en) 1977-01-31
FR2319365B1 (nl) 1979-10-12
NO762655L (nl) 1977-02-01
ATA563476A (de) 1977-12-15
DK345076A (da) 1977-02-01
NL7608526A (nl) 1977-02-02
SE7608585L (sv) 1977-02-01
ES450276A1 (es) 1977-10-01
IL50166A0 (en) 1976-09-30
PT65406B (en) 1978-02-06
BE844713A (fr) 1977-01-31

Similar Documents

Publication Publication Date Title
CH633558A5 (de) Verfahren zur herstellung neuer cephalosporinderivate.
EP0137441A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
DE1795188B2 (de) 3-Alkoxymethylcephalosporine, Verfahren zu deren Herstellung und die diese enthaltenden pharmazeutischen Zusammensetzungen
DE2408698A1 (de) 7-alpha-aminoacyl-3-halogencephalosporine und verfahren zu deren herstellung
EP0111934A2 (de) Cephalosporinderivate und Verfahren zu ihrer Herstellung
EP0246187B1 (de) 2-Pyridyl-penem-Verbindungen
CH622806A5 (nl)
DD208155A5 (de) Neue ester mit einer p=n-y-gruppierung
EP0107138B1 (de) Neue Cephalosporine und Verfahren zu ihrer Herstellung
CH669384A5 (nl)
EP0000392B1 (de) Cephalosporin und Penicillin-derivate, Verfahren zu deren Herstellung, und deren pharmazeutische Präparate
DE2312041A1 (de) Penicilline, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
CH619233A5 (nl)
DE2700271A1 (de) Thienopyridinderivate
EP0008343B1 (de) Cephalosporinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
CH620444A5 (en) Process for the preparation of bicyclic unsaturated thiaaza compounds
CH644867A5 (de) In der 3- und 7-stellung substituierte cephemcarbonsaeuren.
DE2461933A1 (de) Cephalosporinanaloga
AT353971B (de) Verfahren zur herstellung von neuen, eine niederalkylsulfonylaminogruppe enthaltenden cephalosporinen
AT345980B (de) Verfahren zur herstellung von neuen cephalosporinen
CH624121A5 (en) Process for the preparation of 7 beta -(D-2-amino-2-(1,4-cyclohexadienyl)-acetylamino)-3-Hal-3-cephem-4-ca rboxylic acids
DE3518848A1 (de) Aminoaethylthioverbindungen
AT349146B (de) Verfahren zur herstellung von neuen, eine alkylsulfonylaminogruppe enthaltenden cephalosporinen
EP0136266A2 (de) 7beta-Acylamido-3-cephem-4-carbonsäureester, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
EP0090240A2 (de) 7-Alpha-Aminoacyl-3-chlorcephalosporine, Verfahren zu ihrer Herstellung sowie ihrer Verwendung als Arzneimittel

Legal Events

Date Code Title Description
PL Patent ceased