CH616691A5 - Process for the preparation of steroid compounds and their use. - Google Patents

Process for the preparation of steroid compounds and their use. Download PDF

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Publication number
CH616691A5
CH616691A5 CH1837071A CH1837071A CH616691A5 CH 616691 A5 CH616691 A5 CH 616691A5 CH 1837071 A CH1837071 A CH 1837071A CH 1837071 A CH1837071 A CH 1837071A CH 616691 A5 CH616691 A5 CH 616691A5
Authority
CH
Switzerland
Prior art keywords
group
compounds
methyl
hydroxy
methyl group
Prior art date
Application number
CH1837071A
Other languages
German (de)
English (en)
Inventor
Martin Christopher Cook
Robin Lawrence
Gordon Hanley Phillipps
Anne Christine Hunter
Christopher Earle Newall
Leslie Stephenson
Niall Galbraith Weir
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB6006470A external-priority patent/GB1380246A/en
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of CH616691A5 publication Critical patent/CH616691A5/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CH1837071A 1970-12-17 1971-12-16 Process for the preparation of steroid compounds and their use. CH616691A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB6006470A GB1380246A (en) 1970-12-17 1970-12-17 3alpha-hydroxy-androstanes and esters thereof

Publications (1)

Publication Number Publication Date
CH616691A5 true CH616691A5 (en) 1980-04-15

Family

ID=10484935

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1837071A CH616691A5 (en) 1970-12-17 1971-12-16 Process for the preparation of steroid compounds and their use.

Country Status (9)

Country Link
AU (1) AU473167B2 (xx)
BE (1) BE776786A (xx)
CA (1) CA988508A (xx)
CH (1) CH616691A5 (xx)
DE (1) DE2162555A1 (xx)
DK (1) DK133682B (xx)
FR (1) FR2118117B1 (xx)
IL (1) IL38376A (xx)
ZA (1) ZA718466B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434919A (en) * 1972-06-15 1976-05-12 Glaxo Lab Ltd 3alpha-hydroxy androstanes
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
EP0701444B1 (en) * 1993-05-24 2010-04-07 Purdue Pharma Ltd. Methods and compositions for inducing sleep
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH273860A (de) * 1942-04-25 1951-02-28 Nv Organon Verfahren zur Herstellung einer im Ring C eine sauerstoffhaltige Gruppe enthaltenden Verbindung der Cyclopentanopolyhydrophenanthren-Reihe.
US2824871A (en) * 1951-11-29 1958-02-25 Upjohn Co Steroid compounds and process
FR1281205A (fr) * 1956-12-21 1962-01-12 Organon Nv Procédé d'obtention de composés de la série du prégnane

Also Published As

Publication number Publication date
FR2118117A1 (xx) 1972-07-28
DE2162555A1 (de) 1972-06-22
ZA718466B (en) 1973-08-29
BE776786A (fr) 1972-06-16
AU3696271A (en) 1973-06-21
FR2118117B1 (xx) 1975-12-26
CA988508A (en) 1976-05-04
AU473167B2 (en) 1976-06-17
IL38376A0 (en) 1972-02-29
DK133682B (da) 1976-06-28
DK133682C (xx) 1976-12-20
IL38376A (en) 1977-07-31

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PL Patent ceased