CH609038A5 - Process for the preparation of novel benzylamines - Google Patents
Process for the preparation of novel benzylaminesInfo
- Publication number
- CH609038A5 CH609038A5 CH529177A CH529177A CH609038A5 CH 609038 A5 CH609038 A5 CH 609038A5 CH 529177 A CH529177 A CH 529177A CH 529177 A CH529177 A CH 529177A CH 609038 A5 CH609038 A5 CH 609038A5
- Authority
- CH
- Switzerland
- Prior art keywords
- formula
- benzylamines
- novel
- preparation
- effect
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/24—Camphidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
The preparation of novel benzylamines of the formula I <IMAGE> in which the symbols R1 to R5 have the meanings stated in Claim 1, as well as their physiologically tolerated acid addition salts with inorganic or organic acids is described. The compounds of the formula I have valuable pharmacological properties, especially an antiulcer effect, a secretolytic, cough-suppressant effect and an effect enhancing the production of the surfactant or antiatelectasis factor in the alveoli. The compounds of the formula I are prepared by reacting an appropriately substituted benzyl alcohol with an amide of the formula O=P(NR4R5)3.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742405322 DE2405322A1 (en) | 1974-02-05 | 1974-02-05 | NEW METHODS FOR MANUFACTURING BENZYLAMINES |
Publications (1)
Publication Number | Publication Date |
---|---|
CH609038A5 true CH609038A5 (en) | 1979-02-15 |
Family
ID=5906596
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH528877A CH609035A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH529077A CH609037A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH528977A CH609036A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH529277A CH609329A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH529477A CH592609A5 (en) | 1974-02-05 | 1974-04-09 | |
CH529177A CH609038A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH529377A CH617662A5 (en) | 1974-02-05 | 1977-04-28 | Process for the preparation of novel benzylamines |
Family Applications Before (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH528877A CH609035A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH529077A CH609037A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH528977A CH609036A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH529277A CH609329A5 (en) | 1974-02-05 | 1974-04-09 | Process for the preparation of novel benzylamines |
CH529477A CH592609A5 (en) | 1974-02-05 | 1974-04-09 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH529377A CH617662A5 (en) | 1974-02-05 | 1977-04-28 | Process for the preparation of novel benzylamines |
Country Status (5)
Country | Link |
---|---|
CH (7) | CH609035A5 (en) |
DE (1) | DE2405322A1 (en) |
ES (1) | ES433900A1 (en) |
PL (7) | PL95668B1 (en) |
SU (7) | SU521838A3 (en) |
-
1974
- 1974-02-05 DE DE19742405322 patent/DE2405322A1/en active Pending
- 1974-04-09 CH CH528877A patent/CH609035A5/en not_active IP Right Cessation
- 1974-04-09 CH CH529077A patent/CH609037A5/en not_active IP Right Cessation
- 1974-04-09 CH CH528977A patent/CH609036A5/en not_active IP Right Cessation
- 1974-04-09 CH CH529277A patent/CH609329A5/en not_active IP Right Cessation
- 1974-04-09 CH CH529477A patent/CH592609A5/xx not_active IP Right Cessation
- 1974-04-09 CH CH529177A patent/CH609038A5/en not_active IP Right Cessation
- 1974-04-12 PL PL18143474A patent/PL95668B1/en unknown
- 1974-04-12 PL PL18143574A patent/PL94231B1/pl unknown
- 1974-04-12 PL PL18143674A patent/PL94232B1/pl unknown
- 1974-04-12 PL PL18143374A patent/PL96785B1/en unknown
- 1974-04-12 PL PL18143774A patent/PL94234B1/pl unknown
- 1974-04-12 PL PL18143274A patent/PL94279B1/pl unknown
- 1974-04-12 PL PL18143174A patent/PL96532B1/en unknown
-
1975
- 1975-01-17 ES ES433900A patent/ES433900A1/en not_active Expired
- 1975-01-30 SU SU2101063A patent/SU521838A3/en active
- 1975-01-30 SU SU7502101047A patent/SU575021A3/en active
- 1975-01-30 SU SU752101062A patent/SU640657A3/en active
- 1975-01-30 SU SU2101049A patent/SU520035A3/en active
- 1975-01-30 SU SU2101064A patent/SU528866A3/en active
- 1975-01-30 SU SU2101058A patent/SU523634A3/en active
- 1975-01-30 SU SU2101060A patent/SU527134A3/en active
-
1977
- 1977-04-28 CH CH529377A patent/CH617662A5/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PL95668B1 (en) | 1977-11-30 |
SU521838A3 (en) | 1976-07-15 |
PL96785B1 (en) | 1978-01-31 |
SU520035A3 (en) | 1976-06-30 |
SU523634A3 (en) | 1976-07-30 |
DE2405322A1 (en) | 1975-09-04 |
ES433900A1 (en) | 1976-12-01 |
PL94279B1 (en) | 1977-07-30 |
PL96532B1 (en) | 1977-12-31 |
SU527134A3 (en) | 1976-08-30 |
CH609037A5 (en) | 1979-02-15 |
PL94232B1 (en) | 1977-07-30 |
CH609036A5 (en) | 1979-02-15 |
SU575021A3 (en) | 1977-09-30 |
PL94234B1 (en) | 1977-07-30 |
SU528866A3 (en) | 1976-09-15 |
CH592609A5 (en) | 1977-10-31 |
PL94231B1 (en) | 1977-07-30 |
CH609035A5 (en) | 1979-02-15 |
SU640657A3 (en) | 1978-12-30 |
CH617662A5 (en) | 1980-06-13 |
CH609329A5 (en) | 1979-02-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |