CA999866A - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
CA999866A
CA999866A CA102,060A CA102060A CA999866A CA 999866 A CA999866 A CA 999866A CA 102060 A CA102060 A CA 102060A CA 999866 A CA999866 A CA 999866A
Authority
CA
Canada
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA102,060A
Other languages
English (en)
Other versions
CA102060S (en
Inventor
Alfred Rheiner (Jr.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA999866A publication Critical patent/CA999866A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA102,060A 1970-01-06 1971-01-06 Isoquinoline derivatives Expired CA999866A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
CA999866A true CA999866A (en) 1976-11-16

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
CA102,060A Expired CA999866A (en) 1970-01-06 1971-01-06 Isoquinoline derivatives

Country Status (19)

Country Link
JP (1) JPS5515476B1 (en:Method)
AT (1) AT303041B (en:Method)
BE (1) BE761219A (en:Method)
CA (1) CA999866A (en:Method)
CH (2) CH527194A (en:Method)
DE (1) DE2062001C2 (en:Method)
DK (1) DK125021B (en:Method)
ES (1) ES387016A1 (en:Method)
FI (1) FI49503C (en:Method)
FR (1) FR2081412B1 (en:Method)
GB (1) GB1335261A (en:Method)
IE (1) IE34859B1 (en:Method)
IL (1) IL35916A (en:Method)
NL (1) NL171444C (en:Method)
NO (1) NO135315C (en:Method)
PH (1) PH9682A (en:Method)
SE (3) SE368401B (en:Method)
YU (1) YU33660B (en:Method)
ZA (1) ZA708590B (en:Method)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
CA2389300C (en) * 1999-11-03 2010-06-08 Albany Molecular Research, Inc. 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
KR100885986B1 (ko) 1999-11-03 2009-03-03 에이엠알 테크놀로지, 인크. 노르에피네프린, 도파민 및 세로토닌의 재흡수를 방지하기위한 아릴 및 헤테로아릴 치환된테트라하이드로이소퀴놀린 및 이들의 용도
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
BR0112350A (pt) 2000-07-11 2003-06-24 Albany Molecular Res Inc Composto, composição farmacêutica, e, método de tratar um animal afligido por um distúrbio neurológico ou psicológico
AU2005274927B2 (en) 2004-07-15 2011-11-03 Albany Molecular Research, Inc. Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
PT1899334E (pt) 2005-06-17 2008-11-06 Janssen Pharmaceutica Nv Compostos de naftiridina
JP5258561B2 (ja) 2005-07-15 2013-08-07 アルバニー モレキュラー リサーチ， インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
KR20120023072A (ko) 2009-05-12 2012-03-12 브리스톨-마이어스 스큅 컴퍼니 （Ｓ）-7-（〔1,2,4〕트리아졸〔1,5-ａ〕피리딘-6-일）-4-（3,4-디클로로페닐）-1,2,3,4-테트라하이드로이소퀴놀린의 결정형 및 이의 용도
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
FR2081412B1 (en:Method) 1974-04-12
PH9682A (en) 1976-02-10
SE368401B (en:Method) 1974-07-01
DE2062001A1 (de) 1971-07-15
ES387016A1 (es) 1976-05-01
IE34859B1 (en) 1975-09-03
SE386672B (sv) 1976-08-16
JPS5515476B1 (en:Method) 1980-04-23
SE399879B (sv) 1978-03-06
CH538477A (de) 1973-06-30
NL171444B (nl) 1982-11-01
NL7018956A (en:Method) 1971-07-08
IL35916A0 (en) 1971-02-25
NO135315B (en:Method) 1976-12-13
NO135315C (en:Method) 1977-03-23
CH527194A (de) 1972-08-31
YU33660B (en) 1977-12-31
BE761219A (fr) 1971-07-05
AT303041B (de) 1972-11-10
FI49503B (en:Method) 1975-04-01
FR2081412A1 (en:Method) 1971-12-03
ZA708590B (en) 1971-09-29
GB1335261A (en) 1973-10-24
NL171444C (nl) 1983-04-05
DK125021B (da) 1972-12-18
IE34859L (en) 1971-07-06
YU1971A (en) 1977-06-30
DE2062001C2 (de) 1986-10-16
FI49503C (fi) 1975-07-10
IL35916A (en) 1973-11-28

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