CA998668A - Derivatives of 1,4-benzodiazepin-2-one and methods for preparation thereof - Google Patents

Derivatives of 1,4-benzodiazepin-2-one and methods for preparation thereof

Info

Publication number
CA998668A
CA998668A CA151,758A CA151758A CA998668A CA 998668 A CA998668 A CA 998668A CA 151758 A CA151758 A CA 151758A CA 998668 A CA998668 A CA 998668A
Authority
CA
Canada
Prior art keywords
benzodiazepin
derivatives
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA151,758A
Other languages
English (en)
Other versions
CA151758S (en
Inventor
Franjo Kajfez
Vitomir Sunjic
Tomislav Kovac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crc Di Ricerca Chimica Sa Cia
Original Assignee
Crc Di Ricerca Chimica Sa Cia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Di Ricerca Chimica Sa Cia filed Critical Crc Di Ricerca Chimica Sa Cia
Application granted granted Critical
Publication of CA998668A publication Critical patent/CA998668A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
CA151,758A 1971-09-15 1972-09-14 Derivatives of 1,4-benzodiazepin-2-one and methods for preparation thereof Expired CA998668A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1349871A CH559189A5 (ja) 1971-09-15 1971-09-15
CH785672A CH588473A5 (ja) 1971-09-15 1972-05-26

Publications (1)

Publication Number Publication Date
CA998668A true CA998668A (en) 1976-10-19

Family

ID=25702345

Family Applications (1)

Application Number Title Priority Date Filing Date
CA151,758A Expired CA998668A (en) 1971-09-15 1972-09-14 Derivatives of 1,4-benzodiazepin-2-one and methods for preparation thereof

Country Status (16)

Country Link
US (1) US3852274A (ja)
JP (2) JPS5241274B2 (ja)
AR (1) AR206584A1 (ja)
AT (2) AT327201B (ja)
BE (1) BE788899A (ja)
CA (1) CA998668A (ja)
CH (2) CH559189A5 (ja)
DE (4) DE2265140C3 (ja)
ES (1) ES406637A1 (ja)
FR (1) FR2154508B1 (ja)
GB (1) GB1407493A (ja)
HU (1) HU166372B (ja)
IL (1) IL40312A (ja)
NL (2) NL152552B (ja)
NO (1) NO137895C (ja)
SE (1) SE7601317L (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859771A (en) * 1986-07-14 1989-08-22 Merck & Co., Inc. Process for resolution and racemization of amines with acidic α-hydrogens
RU2701557C2 (ru) * 2017-11-24 2019-09-30 Общество С Ограниченной Ответственностью "Инновационные Фармакологические Разработки" (Ооо "Ифар") Производные 1,4-бензодиазепин-2-она и их применение

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198789A (en) * 1965-08-03 Certain j-amino-s-phenyl-l,j-dihydro-zh- l,x-benzxraazepin-z-qnx c compounds
BE621819A (ja) * 1961-08-29
GB1034872A (en) * 1962-04-16 1966-07-06 American Home Prod Benzodiazepine derivatives
NL298071A (ja) * 1963-06-04
US3450695A (en) * 1967-01-19 1969-06-17 Hoffmann La Roche Benzodiazepine compounds and methods for their production

Also Published As

Publication number Publication date
DE2264794A1 (de) 1975-01-23
NO137895B (no) 1978-02-06
DE2264794B2 (de) 1977-04-21
DE2245412A1 (de) 1973-03-22
SE7601317L (sv) 1976-02-06
ES406637A1 (es) 1975-10-01
JPS4844288A (ja) 1973-06-26
DE2265139B2 (de) 1977-11-17
GB1407493A (en) 1975-09-24
CH588473A5 (ja) 1977-06-15
IL40312A0 (en) 1972-11-28
US3852274A (en) 1974-12-03
DE2245412C3 (de) 1978-04-20
BE788899A (fr) 1973-01-02
IL40312A (en) 1976-09-30
JPS51125093A (en) 1976-11-01
DE2265139A1 (de) 1976-12-09
CH559189A5 (ja) 1975-02-28
DE2245412B2 (de) 1977-08-25
DE2265342B2 (de) 1979-06-28
NO137895C (no) 1978-05-16
DE2265342A1 (de) 1977-09-15
FR2154508A1 (ja) 1973-05-11
DE2265140B2 (de) 1977-11-03
DE2265140A1 (de) 1976-11-11
DE2265342C3 (de) 1980-03-13
ATA794072A (de) 1975-04-15
JPS5241274B2 (ja) 1977-10-17
AR206584A1 (es) 1976-08-06
DE2265140C3 (de) 1978-07-06
AT327201B (de) 1976-01-26
NL152552B (nl) 1977-03-15
FR2154508B1 (ja) 1975-11-28
HU166372B (ja) 1975-03-28
NL7614227A (nl) 1977-04-29
DE2265139C3 (de) 1978-07-13
NL7212584A (ja) 1973-03-19
AT327209B (de) 1976-01-26

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