CH588473A5 - - Google Patents

Info

Publication number
CH588473A5
CH588473A5 CH785672A CH785672A CH588473A5 CH 588473 A5 CH588473 A5 CH 588473A5 CH 785672 A CH785672 A CH 785672A CH 785672 A CH785672 A CH 785672A CH 588473 A5 CH588473 A5 CH 588473A5
Authority
CH
Switzerland
Application number
CH785672A
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE788899D priority Critical patent/BE788899A/xx
Priority to CH1349871A priority patent/CH559189A5/xx
Priority to AR244132A priority patent/AR206584A1/es
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Priority to CH785672A priority patent/CH588473A5/xx
Priority to IL40312A priority patent/IL40312A/en
Priority to GB4165672A priority patent/GB1407493A/en
Priority to ES406637A priority patent/ES406637A1/es
Priority to FR7232474A priority patent/FR2154508B1/fr
Priority to HUCA336A priority patent/HU166372B/hu
Priority to US00289143A priority patent/US3852274A/en
Priority to CA151,758A priority patent/CA998668A/en
Priority to NO3268/72A priority patent/NO137895C/no
Priority to DE2265139A priority patent/DE2265139C3/de
Priority to DE2265342A priority patent/DE2265342C3/de
Priority to AT794072A priority patent/AT327201B/de
Priority to DE2245412A priority patent/DE2245412C3/de
Priority to NL727212584A priority patent/NL152552B/xx
Priority to DE19722264794 priority patent/DE2264794C3/de
Priority to AT876974*7A priority patent/AT327209B/de
Priority to DE2265140A priority patent/DE2265140C3/de
Priority to JP47093143A priority patent/JPS5241274B2/ja
Priority to AR25022273A priority patent/AR204979A1/es
Priority to AR26048075A priority patent/AR210741A1/es
Priority to AR26047975A priority patent/AR211524A1/es
Priority to SE7601317A priority patent/SE7601317L/xx
Priority to JP51043492A priority patent/JPS51125093A/ja
Priority to NL7614227A priority patent/NL7614227A/xx
Priority to FI770990A priority patent/FI770990A/fi
Publication of CH588473A5 publication Critical patent/CH588473A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
CH785672A 1971-09-15 1972-05-26 CH588473A5 (xx)

Priority Applications (28)

Application Number Priority Date Filing Date Title
BE788899D BE788899A (fr) 1971-09-15 Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs
CH1349871A CH559189A5 (xx) 1971-09-15 1971-09-15
AR244132A AR206584A1 (es) 1971-09-15 1972-01-01 Un procedimiento para la obtencion de derivados de 5-fenil-1,4-benzodiazepin-2-onas
CH785672A CH588473A5 (xx) 1971-09-15 1972-05-26
IL40312A IL40312A (en) 1971-09-15 1972-09-06 1,3-dihydro-5-phenyl-2h-1,4-benzodiazepin-2-one derivatives,processes for their preparation and pharmaceutical compositions containing them
GB4165672A GB1407493A (en) 1971-09-15 1972-09-07 Benzodiazepine derivatives
ES406637A ES406637A1 (es) 1971-09-15 1972-09-13 Un procedimiento para la obtencion de derivados de las 1,4 - benzodiazepin-2-onas.
FR7232474A FR2154508B1 (xx) 1971-09-15 1972-09-13
HUCA336A HU166372B (xx) 1971-09-15 1972-09-14
US00289143A US3852274A (en) 1971-09-15 1972-09-14 Derivatives of 1,4-benzodiazepin-2-one and methods for preparation thereof
CA151,758A CA998668A (en) 1971-09-15 1972-09-14 Derivatives of 1,4-benzodiazepin-2-one and methods for preparation thereof
NO3268/72A NO137895C (no) 1971-09-15 1972-09-14 Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,4-benzodiazepin-2-on-derivater
DE2265342A DE2265342C3 (de) 1971-09-15 1972-09-15 7-Chlor-l-methyl-5-phenyl-3-(2-methylpyrimidinyl)-13-dihydro-2H-1 ^-benzodiazepin^-on-chlorid
DE2265139A DE2265139C3 (de) 1971-09-15 1972-09-15 Substituierte l-Methyl-5-phenyl-13-Dihydro-2H-1,4-benzodiazepin-2-on-derivate
AT794072A AT327201B (de) 1971-09-15 1972-09-15 Verfahren zur herstellung von neuen 1,4-benzodiazepin-2-on-derivaten
DE2245412A DE2245412C3 (de) 1971-09-15 1972-09-15 7-Chlor-5-phenyl-3-(3-carbamoyIpyridinium)-13-dihydro-2H-1,4-benzodiazepin-2-on halogenidverbindungen und Verfahren zur Herstellung derselben
NL727212584A NL152552B (nl) 1971-09-15 1972-09-15 Werkwijze ter bereiding van een geneesmiddel onder toepassing van een 1,4-benzodiazepin-2-on verbinding.
DE19722264794 DE2264794C3 (de) 1971-09-15 1972-09-15 3-Hydroxyalkoxy-7<hlor-5-phenyl-13dihydro-2H-l,4-benzodiazepin-2-on-Derivate
AT876974*7A AT327209B (de) 1971-09-15 1972-09-15 Verfahren zur herstellung von neuen 1,4-benzodiazepin-2-on-derivaten
DE2265140A DE2265140C3 (de) 1971-09-15 1972-09-15 7-Chlor-l -methyl-S-phenyl-Spyridinium-l^-dihydro-2H-l,4-benzodiazepin-2-on-halogenide
JP47093143A JPS5241274B2 (xx) 1971-09-15 1972-09-16
AR25022273A AR204979A1 (es) 1972-05-26 1973-01-01 Procedimiento para la obtencion de derivados de 1 3-dihidro-7-halo-5-fenil-1,4-benzodiazepin-2-ona
AR26048075A AR210741A1 (es) 1972-05-26 1975-09-22 Un procedimiento para la obtencion de compuestos derivados 7 halo-5 o-halofenil o fenil 3 trihaloacetoxi 1,4 benzodiazepin 2-ona
AR26047975A AR211524A1 (es) 1972-05-26 1975-09-22 Un procedimiento para la obtencion de derivados de 7-halo-5-(-halofenil o fenil)-3-o-(2-hidroxietil)o 3-o-(2,3-dihidroxipropil)o 3-o-(2,3-isopropilidendioxi-propilo)-1,4-benzodiazepin-2-ona
SE7601317A SE7601317L (sv) 1971-09-15 1976-02-06 1,4-bensodiazepin-2-onderivat
JP51043492A JPS51125093A (en) 1971-09-15 1976-04-15 Production of 1*44 benzodiazepine derivatives
NL7614227A NL7614227A (nl) 1971-09-15 1976-12-21 Werkwijze ter bereiding van een geneesmiddel onder toepassing van een 1,4-benzodiazepin-2-on verbin- ding.
FI770990A FI770990A (xx) 1971-09-15 1977-03-30

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1349871A CH559189A5 (xx) 1971-09-15 1971-09-15
CH785672A CH588473A5 (xx) 1971-09-15 1972-05-26

Publications (1)

Publication Number Publication Date
CH588473A5 true CH588473A5 (xx) 1977-06-15

Family

ID=25702345

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1349871A CH559189A5 (xx) 1971-09-15 1971-09-15
CH785672A CH588473A5 (xx) 1971-09-15 1972-05-26

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1349871A CH559189A5 (xx) 1971-09-15 1971-09-15

Country Status (16)

Country Link
US (1) US3852274A (xx)
JP (2) JPS5241274B2 (xx)
AR (1) AR206584A1 (xx)
AT (2) AT327209B (xx)
BE (1) BE788899A (xx)
CA (1) CA998668A (xx)
CH (2) CH559189A5 (xx)
DE (4) DE2265139C3 (xx)
ES (1) ES406637A1 (xx)
FR (1) FR2154508B1 (xx)
GB (1) GB1407493A (xx)
HU (1) HU166372B (xx)
IL (1) IL40312A (xx)
NL (2) NL152552B (xx)
NO (1) NO137895C (xx)
SE (1) SE7601317L (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859771A (en) * 1986-07-14 1989-08-22 Merck & Co., Inc. Process for resolution and racemization of amines with acidic α-hydrogens
RU2701557C2 (ru) * 2017-11-24 2019-09-30 Общество С Ограниченной Ответственностью "Инновационные Фармакологические Разработки" (Ооо "Ифар") Производные 1,4-бензодиазепин-2-она и их применение

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198789A (en) * 1965-08-03 Certain j-amino-s-phenyl-l,j-dihydro-zh- l,x-benzxraazepin-z-qnx c compounds
BE621819A (xx) * 1961-08-29
GB1034872A (en) * 1962-04-16 1966-07-06 American Home Prod Benzodiazepine derivatives
NL298071A (xx) * 1963-06-04
US3450695A (en) * 1967-01-19 1969-06-17 Hoffmann La Roche Benzodiazepine compounds and methods for their production

Also Published As

Publication number Publication date
NO137895B (no) 1978-02-06
AR206584A1 (es) 1976-08-06
DE2265342B2 (de) 1979-06-28
NL152552B (nl) 1977-03-15
AT327209B (de) 1976-01-26
DE2265139C3 (de) 1978-07-13
DE2265139B2 (de) 1977-11-17
DE2264794B2 (de) 1977-04-21
FR2154508A1 (xx) 1973-05-11
DE2265140B2 (de) 1977-11-03
SE7601317L (sv) 1976-02-06
AT327201B (de) 1976-01-26
DE2245412A1 (de) 1973-03-22
CH559189A5 (xx) 1975-02-28
NO137895C (no) 1978-05-16
CA998668A (en) 1976-10-19
HU166372B (xx) 1975-03-28
NL7614227A (nl) 1977-04-29
ATA794072A (de) 1975-04-15
DE2265342A1 (de) 1977-09-15
DE2265140A1 (de) 1976-11-11
DE2265342C3 (de) 1980-03-13
US3852274A (en) 1974-12-03
FR2154508B1 (xx) 1975-11-28
DE2245412B2 (de) 1977-08-25
IL40312A0 (en) 1972-11-28
NL7212584A (xx) 1973-03-19
DE2265139A1 (de) 1976-12-09
DE2265140C3 (de) 1978-07-06
IL40312A (en) 1976-09-30
BE788899A (fr) 1973-01-02
DE2264794A1 (de) 1975-01-23
JPS51125093A (en) 1976-11-01
JPS4844288A (xx) 1973-06-26
JPS5241274B2 (xx) 1977-10-17
ES406637A1 (es) 1975-10-01
GB1407493A (en) 1975-09-24
DE2245412C3 (de) 1978-04-20

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Legal Events

Date Code Title Description
PL Patent ceased