BE788899A - Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs - Google Patents

Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs

Info

Publication number
BE788899A
BE788899A BE788899DA BE788899A BE 788899 A BE788899 A BE 788899A BE 788899D A BE788899D A BE 788899DA BE 788899 A BE788899 A BE 788899A
Authority
BE
Belgium
Prior art keywords
tranquilizers
sedatives
benzodiazepine
preparation
derivatives useful
Prior art date
Application number
Other languages
English (en)
French (fr)
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE788899A publication Critical patent/BE788899A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
BE788899D 1971-09-15 Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs BE788899A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1349871A CH559189A5 (ja) 1971-09-15 1971-09-15
CH785672A CH588473A5 (ja) 1971-09-15 1972-05-26

Publications (1)

Publication Number Publication Date
BE788899A true BE788899A (fr) 1973-01-02

Family

ID=25702345

Family Applications (1)

Application Number Title Priority Date Filing Date
BE788899D BE788899A (fr) 1971-09-15 Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs

Country Status (16)

Country Link
US (1) US3852274A (ja)
JP (2) JPS5241274B2 (ja)
AR (1) AR206584A1 (ja)
AT (2) AT327201B (ja)
BE (1) BE788899A (ja)
CA (1) CA998668A (ja)
CH (2) CH559189A5 (ja)
DE (4) DE2265140C3 (ja)
ES (1) ES406637A1 (ja)
FR (1) FR2154508B1 (ja)
GB (1) GB1407493A (ja)
HU (1) HU166372B (ja)
IL (1) IL40312A (ja)
NL (2) NL152552B (ja)
NO (1) NO137895C (ja)
SE (1) SE7601317L (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859771A (en) * 1986-07-14 1989-08-22 Merck & Co., Inc. Process for resolution and racemization of amines with acidic α-hydrogens
RU2701557C2 (ru) * 2017-11-24 2019-09-30 Общество С Ограниченной Ответственностью "Инновационные Фармакологические Разработки" (Ооо "Ифар") Производные 1,4-бензодиазепин-2-она и их применение

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198789A (en) * 1965-08-03 Certain j-amino-s-phenyl-l,j-dihydro-zh- l,x-benzxraazepin-z-qnx c compounds
BE621819A (ja) * 1961-08-29
GB1034872A (en) * 1962-04-16 1966-07-06 American Home Prod Benzodiazepine derivatives
NL298071A (ja) * 1963-06-04
US3450695A (en) * 1967-01-19 1969-06-17 Hoffmann La Roche Benzodiazepine compounds and methods for their production

Also Published As

Publication number Publication date
CA998668A (en) 1976-10-19
DE2264794A1 (de) 1975-01-23
NO137895B (no) 1978-02-06
DE2264794B2 (de) 1977-04-21
DE2245412A1 (de) 1973-03-22
SE7601317L (sv) 1976-02-06
ES406637A1 (es) 1975-10-01
JPS4844288A (ja) 1973-06-26
DE2265139B2 (de) 1977-11-17
GB1407493A (en) 1975-09-24
CH588473A5 (ja) 1977-06-15
IL40312A0 (en) 1972-11-28
US3852274A (en) 1974-12-03
DE2245412C3 (de) 1978-04-20
IL40312A (en) 1976-09-30
JPS51125093A (en) 1976-11-01
DE2265139A1 (de) 1976-12-09
CH559189A5 (ja) 1975-02-28
DE2245412B2 (de) 1977-08-25
DE2265342B2 (de) 1979-06-28
NO137895C (no) 1978-05-16
DE2265342A1 (de) 1977-09-15
FR2154508A1 (ja) 1973-05-11
DE2265140B2 (de) 1977-11-03
DE2265140A1 (de) 1976-11-11
DE2265342C3 (de) 1980-03-13
ATA794072A (de) 1975-04-15
JPS5241274B2 (ja) 1977-10-17
AR206584A1 (es) 1976-08-06
DE2265140C3 (de) 1978-07-06
AT327201B (de) 1976-01-26
NL152552B (nl) 1977-03-15
FR2154508B1 (ja) 1975-11-28
HU166372B (ja) 1975-03-28
NL7614227A (nl) 1977-04-29
DE2265139C3 (de) 1978-07-13
NL7212584A (ja) 1973-03-19
AT327209B (de) 1976-01-26

Similar Documents

Publication Publication Date Title
AT327927B (de) Verfahren zur herstellung von neuen 1,5-benzodiazocinen und deren salzen
AT317899B (de) Verfahren zur Herstellung von neuen arylsubstituierten Piperazinylalkylchinazolon-(4)-derivaten und deren Salzen
BE776510A (fr) Procede de preparation en continu d'alcoxysilanes et d'alcoxy-polysiloxanes
AT327212B (de) Verfahren zur herstellung von neuen derivaten des 5,10-iminodibenzocycloheptens und von deren salzen
FR2287435A1 (fr) Procede de preparation de cyclohexane-diones-1,3 et d'alkyl-6-dihydro-3,4-pyranones-2
BE795902A (fr) Procede de preparation du diiodo-3,5 hydroxy-4benzonitrile et de l'iodo-3 hydroxy-4 nitro-5benzonitrile
BE788899A (fr) Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs
BE785055A (fr) Procede de preparation d'alpha-monohydroxylamino- anthraquinoneet d'alpha,alpha'-dihydroxylamino-anthraquinone
BE781474A (fr) Procede de preparation de derives bisubstitues en n' de la n-o-cyanophenyl-formamidine et de leurs sels
BE815971A (fr) Procede de preparation d'amines et d'urees substituees
ZA728821B (en) 8,12-diisoprostanoic acid derivatives and process for their preparation
BE778792A (fr) Derives de dibenzocycloheptadioxolanne utiles notamment comme anti-inflammatoires et antispamodiques et leur procede de preparation
BE841549A (fr) Procede de preparation -de 1,4-benzodiazepines substituees en position2
BE774108A (fr) Derives de l'hydroxocobalamine, procede pour leur preparation et utilisation de ces derives en therapeutique
AT327907B (de) Verfahren zur herstellung von neuen 1,4-athano-2,3-dihydrochinolinderivaten und deren salzen
BE778852A (fr) Procede de preparation d'aminoaryl-urees et d'aminoaryl-thio-urees
ATA416174A (de) Verfahren zur herstellung von 4,4'-dihydroxydiphenyl- (2-pyridyl)-methanestern und deren salzen
ZA73487B (en) Derivatives of 4'-aminomethyl-dibenzo/b,e/-11-oxepine-2'-sprio-1',3'-dioxolane,their method of preparation and their therepautic application
PH11943A (en) 2,2"-anhydro-1-b-d-arabinofuranosyl-5-fluorocytosine salts and process of preparation
AT325609B (de) Verfahren zur herstellung von neuen 1,2,4-oxadiazol-derivaten und von deren salzen
BE806826A (fr) Nouvelles pyrrolo(1,2c)imidazolediones utiles notamment comme sedatifs du systeme nerveux central et tranquilisants et leur procede de preparation
CH550795A (fr) Procede de preparation de derives d'imidocarbonyle.
AT317224B (de) Verfahren zur Herstellung von 1,4-Benzodiazepinderivaten und von deren Salzen
AT333763B (de) Verfahren zur herstellung von neuen 1,2,3,4-tetrahydroisochinolinen und deren salzen
ATA202675A (de) Verfahren zur herstellung von neuen 1,2,3,4-tetrahydroisochinolinen und deren salzen