CA3155599A1 - Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia - Google Patents

Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia

Info

Publication number
CA3155599A1
CA3155599A1 CA3155599A CA3155599A CA3155599A1 CA 3155599 A1 CA3155599 A1 CA 3155599A1 CA 3155599 A CA3155599 A CA 3155599A CA 3155599 A CA3155599 A CA 3155599A CA 3155599 A1 CA3155599 A1 CA 3155599A1
Authority
CA
Canada
Prior art keywords
administration
composition
cah
use according
glucocorticoids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3155599A
Other languages
English (en)
French (fr)
Inventor
Dimitri E Grigoriadis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurocrine Biosciences Inc
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52450623&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3155599(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of CA3155599A1 publication Critical patent/CA3155599A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3155599A 2014-01-21 2015-01-21 Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia Pending CA3155599A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461929941P 2014-01-21 2014-01-21
US61/929,941 2014-01-21
US201461981033P 2014-04-17 2014-04-17
US61/981,033 2014-04-17
US201462069155P 2014-10-27 2014-10-27
US62/069,155 2014-10-27
CA2936974A CA2936974A1 (en) 2014-01-21 2015-01-21 Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2936974A Division CA2936974A1 (en) 2014-01-21 2015-01-21 Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia

Publications (1)

Publication Number Publication Date
CA3155599A1 true CA3155599A1 (en) 2015-07-30

Family

ID=52450623

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3155599A Pending CA3155599A1 (en) 2014-01-21 2015-01-21 Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia
CA2936974A Pending CA2936974A1 (en) 2014-01-21 2015-01-21 Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2936974A Pending CA2936974A1 (en) 2014-01-21 2015-01-21 Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia

Country Status (24)

Country Link
US (5) US20170020877A1 (enExample)
EP (2) EP4450070A1 (enExample)
JP (5) JP6585625B2 (enExample)
KR (2) KR102258522B1 (enExample)
CN (2) CN111228274A (enExample)
AU (4) AU2015209452C1 (enExample)
BR (1) BR112016016975B1 (enExample)
CA (2) CA3155599A1 (enExample)
DK (1) DK3096756T3 (enExample)
ES (1) ES2984706T3 (enExample)
FI (1) FI3096756T3 (enExample)
HR (1) HRP20241046T1 (enExample)
HU (1) HUE068315T2 (enExample)
IL (5) IL304134B2 (enExample)
LT (1) LT3096756T (enExample)
MX (3) MX389004B (enExample)
NZ (1) NZ722122A (enExample)
PL (1) PL3096756T3 (enExample)
PT (1) PT3096756T (enExample)
RS (1) RS65839B1 (enExample)
RU (1) RU2718918C2 (enExample)
SI (1) SI3096756T1 (enExample)
SM (1) SMT202400361T1 (enExample)
WO (1) WO2015112642A1 (enExample)

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CA3155599A1 (en) 2014-01-21 2015-07-30 Neurocrine Biosciences, Inc. Crf1 receptor antagonists for the treatment of congenital adrenal hyperplasia
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BR112020002967A2 (pt) 2017-08-14 2020-08-11 Spruce Biosciences, Inc. antagonistas de receptor de fator de liberação de corticotropina
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JP7532328B2 (ja) * 2018-12-07 2024-08-13 ニューロクライン バイオサイエンシーズ，インコーポレイテッド 先天性副腎過形成を処置するためのｃｒｆ１受容体アンタゴニスト、その医薬製剤および固体形態
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CN118252829A (zh) * 2019-09-27 2024-06-28 纽罗克里生物科学有限公司 Crf受体拮抗剂及使用方法
CN116096373A (zh) * 2020-06-10 2023-05-09 纽罗克里生物科学有限公司 用于治疗先天性肾上腺增生症的crf1受体拮抗剂
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MD20210019A2 (ro) 2021-04-12 2022-10-31 Максим МАСЮТИН Metodă de tratament a hiperplaziei suprarenale congenitale, cauzate de deficit de 21-hidroxilază cu debut tardiv prin regimul de glucocorticoizi adaptat individual
US11708372B2 (en) 2021-11-19 2023-07-25 Spruce Biosciences, Inc. Crystalline composition of tildacerfont and methods of use and preparation thereof

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Also Published As

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DK3096756T3 (da) 2024-08-05
KR102258522B1 (ko) 2021-05-31
AU2015209452A1 (en) 2016-08-04
SMT202400361T1 (it) 2024-11-15
RU2016133972A3 (enExample) 2018-09-26
HRP20241046T1 (hr) 2024-11-08
JP7104743B2 (ja) 2022-07-21
IL296683B2 (en) 2023-12-01
RU2020112197A (ru) 2020-05-21
IL296683A (en) 2022-11-01
IL304134B1 (en) 2024-12-01
EP3096756A1 (en) 2016-11-30
IL296683B1 (en) 2023-08-01
IL246783B (en) 2021-10-31
JP6936825B2 (ja) 2021-09-22
LT3096756T (lt) 2024-08-26
AU2022263460A1 (en) 2022-12-08
US20210361659A1 (en) 2021-11-25
KR20160106176A (ko) 2016-09-09
US11311544B2 (en) 2022-04-26
MX2021012539A (es) 2021-11-12
RU2718918C2 (ru) 2020-04-15
AU2022263460B2 (en) 2024-10-17
AU2015209452B2 (en) 2020-05-07
IL304134B2 (en) 2025-04-01
WO2015112642A1 (en) 2015-07-30
EP3096756B1 (en) 2024-06-12
FI3096756T3 (fi) 2024-08-14
AU2020207774B2 (en) 2022-08-04
US11730739B2 (en) 2023-08-22
NZ722122A (en) 2020-06-26
RU2016133972A (ru) 2018-03-05
AU2015209452C1 (en) 2020-11-05
JP2017503030A (ja) 2017-01-26
ES2984706T3 (es) 2024-10-30
IL304134A (en) 2023-09-01
JP2022010260A (ja) 2022-01-14
KR20210064407A (ko) 2021-06-02
MX389004B (es) 2025-03-20
CN106102740A (zh) 2016-11-09
PL3096756T3 (pl) 2024-10-28
AU2020207774A1 (en) 2020-08-06
RS65839B1 (sr) 2024-09-30
US10905690B2 (en) 2021-02-02
SI3096756T1 (sl) 2024-09-30
MX2022000080A (es) 2022-02-03
IL246783A0 (en) 2016-08-31
AU2024219813A1 (en) 2024-10-10
HUE068315T2 (hu) 2024-12-28
BR112016016975B1 (pt) 2022-12-27
MX2016009499A (es) 2017-02-27
US20210137926A1 (en) 2021-05-13
IL317035A (en) 2025-01-01
JP2019081814A (ja) 2019-05-30
US20190231781A1 (en) 2019-08-01
US20170020877A1 (en) 2017-01-26
BR112016016975A2 (pt) 2017-08-08
CN111228274A (zh) 2020-06-05
JP6585625B2 (ja) 2019-10-02
JP2020138978A (ja) 2020-09-03
CA2936974A1 (en) 2015-07-30
US20240058342A1 (en) 2024-02-22
EP4450070A1 (en) 2024-10-23
JP2024098001A (ja) 2024-07-19
IL286782A (en) 2021-10-31
PT3096756T (pt) 2024-08-26

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