CA3115461A1 - Novel cytokine prodrugs - Google Patents

Novel cytokine prodrugs Download PDF

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Publication number
CA3115461A1
CA3115461A1 CA3115461A CA3115461A CA3115461A1 CA 3115461 A1 CA3115461 A1 CA 3115461A1 CA 3115461 A CA3115461 A CA 3115461A CA 3115461 A CA3115461 A CA 3115461A CA 3115461 A1 CA3115461 A1 CA 3115461A1
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CA
Canada
Prior art keywords
seq
prodrug
moiety
antibody
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3115461A
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English (en)
French (fr)
Inventor
Chunxiao YU
Yuefeng Lu
Jian-Feng Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Askgene Pharma Inc
Original Assignee
Askgene Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Askgene Pharma Inc filed Critical Askgene Pharma Inc
Publication of CA3115461A1 publication Critical patent/CA3115461A1/en
Pending legal-status Critical Current

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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2086—IL-13 to IL-16
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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